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anti-Potassium Voltage-Gated Channel, Isk-Related Family, Member 1 (KCNE1) Antibodies

The product of KCNE1 belongs to the potassium channel KCNE family. Additionally we are shipping KCNE1 Proteins (8) and KCNE1 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KCNE1 3753 P15382
KCNE1 25471 P15383
KCNE1 16509 P23299
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Top anti-KCNE1 Antibodies at antibodies-online.com

Showing 10 out of 63 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated WB Western blot analysis of KCNE1 over-expressed 293 cell line, cotransfected with KCNE1 Validated Chimera RNAi used as specificity and loading control. Western Blot analysis of KCNE1 expression in transfected 293T cell line by KCNE1 monoclonal antibody (M01), clone 5B12. Lane 1: KCNE1 transfected lysate(14.7 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged KCNE1 is approximately 3 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p)   100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Mouse Un-conjugated RNAi, ELISA, WB Western Blot analysis of KCNE1 expression in transfected 293T cell line by KCNE1 monoclonal antibody (M01), clone 5B12.Lane 1: KCNE1 transfected lysate(14.7 KDa).Lane 2: Non-transfected lysate. Western blot analysis of KCNE1 over-expressed 293 cell line, cotransfected with KCNE1 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with KCNE1 monoclonal antibody (M01), clone 5B12. GAPDH ( 36.1 kDa ) used as specificity and loading control. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Human Rabbit Un-conjugated IF, WB 100 μL Log in to see 14 Days
$527.15
Details
Mouse Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of RAW cell line, using KCNE1 antibody. 100 μL Log in to see 9 Days
$302.50
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

KCNE1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-KCNE1 Antibodies

  1. Human Monoclonal KCNE1 Primary Antibody for ELISA - ABIN395293 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 5 references for ABIN395293

  2. Human Monoclonal KCNE1 Primary Antibody for WB - ABIN396530 : Siem, Fagerheim, Jonsrud, Laurent, Teig, Harris, Leren, Früh, Heimdal: Causes of hearing impairment in the Norwegian paediatric cochlear implant program. in International journal of audiology 2010 (PubMed)
    Show all 5 references for ABIN396530

  3. Human Monoclonal KCNE1 Primary Antibody for RNAi, ELISA - ABIN561579 : Wang, Zankov, Jiang, Zhang, Henderson, Tseng: [Ca2+]i elevation and oxidative stress induce KCNQ1 protein translocation from the cytosol to the cell surface and increase slow delayed rectifier (IKs) in cardiac myocytes. in The Journal of biological chemistry 2013 (PubMed)

  4. Human Polyclonal KCNE1 Primary Antibody for IF (p), IHC (p) - ABIN1385530 : Zhao, Xu, Yun, Zhao, Li, Gong, Yuan, Yan, Zhang, Ding, Wang, Zhang, Dong, Xiu, Yang, Liu, Xue, Li: Chronic obstructive sleep apnea causes atrial remodeling in canines: mechanisms and implications. in Basic research in cardiology 2014 (PubMed)

More Antibodies against KCNE1 Interaction Partners

Xenopus laevis Potassium Voltage-Gated Channel, Isk-Related Family, Member 1 (KCNE1) interaction partners

  1. TNIK (Traf2 and Nck-interacting kinase (show TNIK Antibodies)) and MINK (Misshapen/NIKs-related kinase) MAP4K signalling kinases are integral components of both canonical and non-canonical pathways in Xenopus.

  2. KCNE1/KCNQ1 (show KCNQ1 Antibodies) was expressed in Xenopus oocytes with and without beta-catenin (show CTNNB1 Antibodies). Confocal microscopy revealed that beta-catenin (show CTNNB1 Antibodies) enhanced the KCNE1/KCNQ1 (show KCNQ1 Antibodies) protein abundance in the cell membrane.

  3. PIP(2) has a role in KCNE1 modulation of I(Ks) channels that may represent a common mechanism of auxiliary subunit modulation of many ion channels

  4. characterize a new component of the early bioelectrical circuit: the potassium channel (show KCNAB2 Antibodies) KCNQ1 (show KCNQ1 Antibodies) and its accessory subunit KCNE1

  5. phenylboronic acid (PBA) activates KCNQ1 (show KCNQ1 Antibodies)/KCNE1 complexes

Human Potassium Voltage-Gated Channel, Isk-Related Family, Member 1 (KCNE1) interaction partners

  1. Analysis of QT-RR relationship could also evaluate the latent arrhythmogenicity of KCNE1(G38S).

  2. The incidence of AF among the senior Uygur population in Xinjiang territory was correlated with the KCNE1 (G38S) polymorphism, which may be an independent risk factor for Uygur AF patients.

  3. The KCNQ1 (show KCNQ1 Antibodies) F279I mutation induces a gain of function of IKs due to an impaired gating modulation of Kv7.1 (show KCNQ1 Antibodies) induced by KCNE1, leading to a shortening of the cardiac action potential

  4. This study aimed to assess the associations between polymorphisms on KCNE1, KCNQ1 (show KCNQ1 Antibodies), and KCNH2 (show KCNH2 Antibodies) with the risk of AF in a Chinese population.

  5. KCNE1 and KCNE3 (show Kcne3 Antibodies): The yin and yang of voltage-gated K(+) channel (show KCND3 Antibodies) regulation

  6. Two phenylalanine residues on KCNQ1 (show KCNQ1 Antibodies), Phe232 on S4 (VSD) and Phe279 on S5 (pore domain) to be responsible for the gating modulation by KCNE1.

  7. acute application of PUFAs increases Kv7.1 (show KCNQ1 Antibodies)/KCNE1 through a probably direct effect, and shows antiarrhythmic efficacy under IKr block.

  8. IKs phosphorylation and alpha1-AR regulation via activation of calcium-dependent PKC isoforms (cPKC) may be a key mechanism to control channel voltage-dependent activation and consequently action potential duration (APD) in response to adrenergic-stimulus.

  9. KCNE1 distal C-terminus appears essential for the regulation of yotiao (show AKAP9 Antibodies)-mediated PKA phosphorylation.

  10. the KCNE1 112G polymorphism may be a risk factor for AF. KCNE1 112G>A may be useful as a biomarker for predicting the development of AF.

Pig (Porcine) Potassium Voltage-Gated Channel, Isk-Related Family, Member 1 (KCNE1) interaction partners

  1. study demonstrated that in the left ventricle,the level of the transcriptional product of KCNE1 was significantly higher than those of KCNQ1 (show KCNQ1 Antibodies), KCNH2 (show KCNH2 Antibodies), and KCNE2 (show KCNE2 Antibodies)

Rabbit Potassium Voltage-Gated Channel, Isk-Related Family, Member 1 (KCNE1) interaction partners

  1. miR-1 by anti-miR-1 inhibitor oligonucleotides alleviated the downregulation of KCNE1 and KCNB2 (show KCNB2 Antibodies), the shortening of AERP, and the increase in the IKs

Cow (Bovine) Potassium Voltage-Gated Channel, Isk-Related Family, Member 1 (KCNE1) interaction partners

  1. The localization of KCNE1 in the RPE (show RPE Antibodies) basal membrane, where KCNQ5 (show KCNQ5 Antibodies) was previously found to be present, suggests that this beta-subunit (show POLG Antibodies) may contribute to M-type K(+) channels in this membrane.

Mouse (Murine) Potassium Voltage-Gated Channel, Isk-Related Family, Member 1 (KCNE1) interaction partners

  1. The electrophysiological effects of BACE1 (show BACE Antibodies) on KCNQ1 (show KCNQ1 Antibodies) reported here were independent of its enzymatic activity.

  2. KCNE1 and KCNE3 (show Kcne3 Antibodies): The yin and yang of voltage-gated K(+) channel (show KCND3 Antibodies) regulation

  3. KCNE1 and KCNE2 (show KCNE2 Antibodies), auxiliary subunits of voltage-gated potassium channels, undergo sequential cleavage mediated by either alpha-secretase and presenilin(PS)/gamma-secretase or BACE1 (show BACE Antibodies) and PS/gamma-secretase in cells.

  4. In clearance studies the KCNE1 knockout mice had an increased fractional excretion of Na+, Cl-, HCO3(-) and water.

  5. This study confirmed that KCNE1 channels are necessary for K+ secretion in developmental Saccule and Utricle in mice.

  6. both the voltage-dependence and kinetics of gating were found to depend on the relative densities of KCNQ1 (show KCNQ1 Antibodies) and KCNE1, suggesting the heart rhythm may be regulated by the relative expression of the auxiliary subunit

  7. Findings directly implicate triggered electrical activity and spatial and temporal re-entrant mechanisms in the arrhythmogenesis observed in KCNE1 (-/-) hearts.

  8. intestinal Cl(-) secretion is independent from KCNE1 but requires KCNQ1 (show KCNQ1 Antibodies) and in mouse pancreatic acini KCNQ1 (show KCNQ1 Antibodies) probably co-assembled with KCNE1 leads to a voltage-dependent K(+) current that might be of importance for electrolyte and enzyme secretion.

  9. the spatial expression of minK-lacZ (show GLB1 Antibodies) in the adult mouse heart has been shown, for the larger part, to be coincident with the conduction tissues

  10. The transitory transfection of kcne1 restores both Cl- and K+ swelling-activated currents, confirming the implication of KCNE1 protein in the cell-volume regulation in PCT (show UROD Antibodies) cells in primary cultures.

KCNE1 Antigen Profile

Protein Summary

The product of this gene belongs to the potassium channel KCNE family. Potassium ion channels are essential to many cellular functions and show a high degree of diversity, varying in their electrophysiologic and pharmacologic properties. This gene encodes a transmembrane protein known to associate with the product of the KVLQT1 gene to form the delayed rectifier potassium channel. Mutation in this gene are associated with both Jervell and Lange-Nielsen and Romano-Ward forms of long-QT syndrome. Alternatively spliced transcript variants encoding the same protein have been identified.

Gene names and symbols associated with KCNE1

  • potassium voltage-gated channel, Isk-related family, member 1 (kcne1) antibody
  • potassium voltage-gated channel, Isk-related family, member 1 (KCNE1) antibody
  • potassium voltage-gated channel, Isk-related family, member 1 (Kcne1) antibody
  • potassium voltage-gated channel, Isk-related subfamily, member 1 (Kcne1) antibody
  • IsK antibody
  • JLNS antibody
  • JLNS2 antibody
  • KCNE1 antibody
  • LQT2/5 antibody
  • LQT5 antibody
  • m antibody
  • minK antibody
  • nmf190 antibody
  • xkcne1 antibody

Protein level used designations for KCNE1

potassium voltage-gated channel, Isk-related family, member 1 , voltage-gated potassium channel subunit MinK , potassium voltage-gated channel subfamily E member 1 , IKs producing slow voltage-gated potassium channel subunit beta Mink , cardiac delayed rectifier potassium channel protein , delayed rectifier potassium channel subunit IsK , minimal potassium channel , potassium voltage-gated channel, Isk-related subfamily, member 1 , voltage gated potassiun channel accessory subunit , mink , potassium (K+) channel protein, slowly activating (Isk) , potassium voltage-gated channel Shaw-related subfamily member 1 , delayed rectifier potassium channel protein , slow delayed rectifier K+ channel , voltage gated potassium channel accessory subunit cardiac splice , mISK

GENE ID SPECIES
398417 Xenopus laevis
427980 Gallus gallus
474097 Pan troglodytes
100173028 Pongo abelii
3753 Homo sapiens
25471 Rattus norvegicus
493681 Felis catus
397331 Sus scrofa
100126000 Oryctolagus cuniculus
487743 Canis lupus familiaris
528014 Bos taurus
16509 Mus musculus
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