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Potassium Voltage-Gated Channel, Isk-Related Family, Member 4 Proteins (KCNE4)

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Additionally we are shipping KCNE4 Antibodies (42) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KCNE4 23704  
Rat KCNE4 KCNE4 367302  
KCNE4 57814 Q9WTW3
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Top KCNE4 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

KCNE4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
,

More Proteins for Potassium Voltage-Gated Channel, Isk-Related Family, Member 4 (KCNE4) Interaction Partners

Rabbit Potassium Voltage-Gated Channel, Isk-Related Family, Member 4 (KCNE4) interaction partners

  1. Apparent association with BK channel in renal collecting duct

Human Potassium Voltage-Gated Channel, Isk-Related Family, Member 4 (KCNE4) interaction partners

  1. the association of the KCNE4 gene variability with allergic rhinitis

  2. KCNE4 juxtamembrane region is required for interaction with calmodulin (show CALM1 Proteins) and for functional suppression of KCNQ1 (show KCNQ1 Proteins).

  3. MiRP3 modulates Kv4.2 (show KCND2 Proteins) current activation, inactivation and recovery from inactivation. MiRP3 shifts the half-maximal voltage for activation and slows time to peak ~ 100%.

  4. KCNE4 E145D polymorphism may be related to atrial fibrillation.

  5. KCNE4 (potassium voltage-gated channel subfamily E member 4), but not KCNE2 (show KCNE2 Proteins), functions as an inhibitory Kv1.3 (show KCNA3 Proteins) partner in leukocytes.

  6. expressed strongly in heart, skeletal muscle, and kidney, less in placenta, lung, and liver, and weakly in brain and blood cells. Electrophysiological study showed that KCNE4 modulates the activation of the KCNQ1 (show KCNQ1 Proteins) channel.

  7. KCNE4 beta-subunit (show POLG Proteins) has a drastic inhibitory effect on currents generated by Kv1.1 (show KCNA1 Proteins) and Kv1.3 (show KCNA3 Proteins) potassium channels

  8. KCNE4 directly associates with KCNQ1 (show KCNQ1 Proteins), and can co-associate together with KCNE1 (show KCNE1 Proteins) in the same KCNQ1 (show KCNQ1 Proteins) complex to form a 'triple subunit' complex (KCNE1 (show KCNE1 Proteins)-KCNQ1 (show KCNQ1 Proteins)-KCNE4).

  9. MiRP3 (encoded by the KCNE4 gene) plays a role in modulation of BK-dependent urinary potassium excretion.

  10. Specific KCNE4 domains responsible for the inhibitory effects on heterologously expressed KCNQ1 (show KCNQ1 Proteins) were identified. The KCNE4 C-terminus is critical for KCNQ1 (show KCNQ1 Proteins) modulation and physically interacts with KCNQ1 (show KCNQ1 Proteins).

Mouse (Murine) Potassium Voltage-Gated Channel, Isk-Related Family, Member 4 (KCNE4) interaction partners

  1. Kcne4 expression and function are age-, sex- dependent and regulated by 5alpha-dihydrotestosterone.

  2. KCNE4 (potassium voltage-gated channel subfamily E member 4), but not KCNE2 (show KCNE2 Proteins), functions as an inhibitory Kv1.3 (show KCNA3 Proteins) partner in leukocytes.

  3. KCNE4 beta-subunit (show POLG Proteins) has a drastic inhibitory effect on currents generated by Kv1.1 (show KCNA2 Proteins) and Kv1.3 (show KCNA3 Proteins) potassium channels

KCNE4 Protein Profile

Protein Summary

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the embryo and in adult uterus.

Gene names and symbols associated with KCNE4

  • potassium voltage-gated channel, Isk-related family, member 4 (KCNE4)
  • potassium voltage-gated channel, Isk-related family, member 4 (kcne4)
  • potassium voltage-gated channel, Isk-related family, member 4 (Kcne4)
  • potassium voltage-gated channel, Isk-related subfamily, gene 4 (Kcne4)
  • AW487937 protein
  • KCNE4 protein
  • MIRP3 protein
  • si:dkeyp-109h9.3 protein

Protein level used designations for KCNE4

potassium voltage-gated channel, Isk-related family, member 4 , minK-related peptide 3 , potassium voltage-gated channel subfamily E member 4 , MINK-related peptide 3 , cardiac voltage-gated potassium channel accessory subunit 4 , minimum potassium ion channel-related peptide 3 , potassium channel subunit beta MiRP3 , potassium voltage-gated channel, Isk-related subfamily, gene 4

GENE ID SPECIES
397167 Sus scrofa
615761 Bos taurus
706263 Macaca mulatta
771271 Gallus gallus
794240 Danio rerio
100037711 Oryctolagus cuniculus
100195631 Salmo salar
23704 Homo sapiens
488549 Canis lupus familiaris
367302 Rattus norvegicus
57814 Mus musculus
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