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anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) Antibodies

KCNQ1 encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. Additionally we are shipping KCNQ1 Proteins (4) and KCNQ1 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KCNQ1 3784 P51787
KCNQ1 84020 Q9Z0N7
KCNQ1 16535 P97414
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Top anti-KCNQ1 Antibodies at antibodies-online.com

Showing 10 out of 134 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-KCNQ1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB KCNQ1 Antibody (N-term) (ABIN656077) western blot analysis in MDA-MB43... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of KCNQ1 Antibody (N-term) in MDA-MB435 cell lin... 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-KCNQ1 Antibody Titration: 1.25ug/mlELISA Titer: 1:62... WB Suggested Anti-KCNQ1  Antibody Titration: 1.25 µg/mL ELISA Titer: 1... 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of KCNQ1 Antibody (Center) (ABIN652891) in mouse... KCNQ1 Antibody (Center) (ABIN652891) flow cytometric analysis of 293 c... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Hamster Mouse Un-conjugated ICC, IF, IP, IHC, WB KCNQ1 (S37A 10) mink KvLQT1 in T CHO. KCNQ1 human cellline mix. 100 μg Log in to see 3 to 4 Days
$383.90
Details
Human Mouse Un-conjugated FACS, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green... Figure 2: Flow cytometric analysis of MCF-7 cells using KCNQ1 mouse mA... 100 μL Log in to see 3 to 4 Days
$430.10
Details
Hamster Mouse HRP ICC, IF, IP, IHC, WB   100 μg Log in to see 3 to 4 Days
$422.40
Details
Hamster Mouse FITC ICC, IF, IP, IHC, WB   100 μg Log in to see 3 to 4 Days
$426.80
Details

KCNQ1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
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Mouse (Murine) , , , ,
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Top referenced anti-KCNQ1 Antibodies

  1. Hamster Monoclonal KCNQ1 Primary Antibody for ICC, IF - ABIN361766 : Kurokawa, Bankston, Kaihara, Chen, Furukawa, Kass: KCNE variants reveal a critical role of the beta subunit carboxyl terminus in PKA-dependent regulation of the IKs potassium channel. in Channels (Austin, Tex.) 2009 (PubMed)
    Show all 3 references for ABIN361766

  2. Human Monoclonal KCNQ1 Primary Antibody for FACS, ELISA - ABIN969227 : Jiang, Xu, Wang, Toyoda, Liu, Zhang, Robinson, Tseng: Dynamic partnership between KCNQ1 and KCNE1 and influence on cardiac IKs current amplitude by KCNE2. in The Journal of biological chemistry 2009 (PubMed)

  3. Hamster Monoclonal KCNQ1 Primary Antibody for ICC, IF - ABIN2483167 : Lang, Vallon, Knipper, Wangemann: Functional significance of channels and transporters expressed in the inner ear and kidney. in American journal of physiology. Cell physiology 2007 (PubMed)

  4. Human Polyclonal KCNQ1 Primary Antibody for FACS, WB - ABIN652891 : Holm, Gudbjartsson, Arnar, Thorleifsson, Thorgeirsson, Stefansdottir, Gudjonsson, Jonasdottir, Mathiesen, Njølstad, Nyrnes, Wilsgaard, Hald, Hveem, Stoltenberg, Løchen, Kong, Thorsteinsdottir, Stefansson: Several common variants modulate heart rate, PR interval and QRS duration. in Nature genetics 2010 (PubMed)

  5. Cow (Bovine) Polyclonal KCNQ1 Primary Antibody for WB - ABIN2776340 : Du, Li, Tsai, You, Xia: Characterization of binding site of closed-state KCNQ1 potassium channel by homology modeling, molecular docking, and pharmacophore identification. in Biochemical and biophysical research communications 2005 (PubMed)

  6. Human Polyclonal KCNQ1 Primary Antibody for WB - ABIN656077 : Nakajo, Ulbrich, Kubo, Isacoff: Stoichiometry of the KCNQ1 - KCNE1 ion channel complex. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)

  7. Cow (Bovine) Polyclonal KCNQ1 Primary Antibody for WB - ABIN375129 : Yasuda, Miyake, Horikawa, Hara, Osawa, Furuta, Hirota, Mori, Jonsson, Sato, Yamagata, Hinokio, Wang, Tanahashi, Nakamura, Oka, Iwasaki, Iwamoto, Yamada, Seino, Maegawa, Kashiwagi, Takeda, Maeda, Shin, Cho, Park, Lee, Ng, Ma, So, Chan, Lyssenko, Tuomi, Nil: Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus. in Nature genetics 2009 (PubMed)

  8. Cow (Bovine) Polyclonal KCNQ1 Primary Antibody for IHC, WB - ABIN2776085 : Zhou, Tan, Paz, Ogawa, Chou, Hayashi, Nihei, Fishbein, Chen, Lin, Chen: Antiarrhythmic effects of beta3-adrenergic receptor stimulation in a canine model of ventricular tachycardia. in Heart rhythm : the official journal of the Heart Rhythm Society 2008 (PubMed)

More Antibodies against KCNQ1 Interaction Partners

Fruit Fly (Drosophila melanogaster) Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) interaction partners

  1. the single KCNQ channel in Drosophila (dKCNQ) has similar electrophysiological properties to neuronal KCNQ2 (show KCNQ2 Antibodies)/3

  2. Data show that Drosophila KCNQ (dKCNQ) is a slowly activating and slowly-deactivating K(+) current open at sub-threshold potentials that has similar properties to neuronal KCNQ2 (show KCNQ2 Antibodies)/3 with some features of the cardiac KCNQ1/KCNE1 (show KCNE1 Antibodies).

  3. A maternal contribution of KCNQ protein and/or mRNA is essential for early embryonic development

Rabbit Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) interaction partners

  1. The enhanced sensitivity of KCNQ1 gain-of-function mutations for HMR (show NR4A1 Antibodies)-1556 suggests the possibility of selective therapeutic targeting, and a potential proof of principle for genotype-specific treatment of this heritable arrhythmia.

  2. There were substantial transmural gradients in Cav1.2 (show CACNA1C Antibodies), KChIP2 (show KCNIP2 Antibodies), ERG (show KCNH2 Antibodies), KvLQT1, Kir2.1 (show KCNJ2 Antibodies), NCX1 (show SLC8A1 Antibodies), SERCA2a (show ATP2A2 Antibodies) and RyR2 (show RYR2 Antibodies) at the mRNA and, in some cases, protein level-in every case the mRNA or protein was more abundant in the epicardium than the endocardium.

Human Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) interaction partners

  1. The KCNQ1 F279I mutation induces a gain of function of IKs due to an impaired gating modulation of Kv7.1 induced by KCNE1 (show KCNE1 Antibodies), leading to a shortening of the cardiac action potential

  2. Data show that voltage-gated potassium channel KCNE3 (show Kcne3 Antibodies) directly affects the S4 movement in potassium channel (show KCNAB2 Antibodies) KCNQ1.

  3. KCNQ1/KCNE3 (show Kcne3 Antibodies) channels make only a small contribution to basolateral conductance in normal colonic crypts, with increased channel activity in UC appearing insufficient to prevent colonic cell depolarization in this disease.

  4. This study showed that KCNQ1 methylation was associated with insulin (show INS Antibodies) resistance after weight loss intervention program in obese stroke.

  5. This study aimed to assess the associations between polymorphisms on KCNE1 (show KCNE1 Antibodies), KCNQ1, and KCNH2 (show KCNH2 Antibodies) with the risk of AF in a Chinese population.

  6. Calml3 (show CALML3 Antibodies) may be a constituent of epithelial KCNQ1 channels and underscores the molecular diversity of endogenous KCNQ1 channels

  7. A novel KCNQ1-G229D mutation identified in a juvenile-onset AF patient altered the IKs activity and kinetics, thereby increasing the arrhythmogenicity to AF.

  8. KCNQ1 rs2237892 polymorphism was associated with gestational diabetes mellitus and glucose levels in Chinese women. (Meta-analysis)

  9. KCNQ1 mutation is a possible genetic etiology of arrhythmogenic dilated cardiomyopathies.

  10. Both gain-of-function and loss-of-function mutations in KCNQ1 enhance the susceptibility to atrial fibrillation.

Xenopus laevis Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) interaction partners

  1. KCNE1 (show KCNE1 Antibodies)/KCNQ1 was expressed in Xenopus oocytes with and without beta-catenin (show CTNNB1 Antibodies). Confocal microscopy revealed that beta-catenin (show CTNNB1 Antibodies) enhanced the KCNE1 (show KCNE1 Antibodies)/KCNQ1 protein abundance in the cell membrane.

  2. results indicate that AMPK (show PRKAA2 Antibodies) inhibits KCNQ1 activity by promoting Nedd4-2 (show NEDD4L Antibodies)-dependent channel ubiquitination and retrieval from the plasma membrane.

  3. S1 constrains S4 in the voltage sensor domain of Kv7.1 K+ channels

  4. characterize a new component of the early bioelectrical circuit: the potassium channel (show KCNAB2 Antibodies) KCNQ1 and its accessory subunit KCNE1 (show KCNE1 Antibodies)

  5. Slow delayed rectifier potassium currents mediated by mutant KCNQ1(Y111C) or KCNQ1(L114P) are paradoxically reduced by serum- and glucocorticoid-inducible kinase 1.

  6. phenylboronic acid (PBA) activates KCNQ1/KCNE1 (show KCNE1 Antibodies) complexes

Mouse (Murine) Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) interaction partners

  1. Loss of methylation at the Kcnq1 imprinted gDMD was strongly associated with trophoblast giant cell (TGC (show TGM2 Antibodies)) expansion.

  2. Data show that disruption of potassium voltage-gated channel, KQT-like subfamily Q, member1 (KCNQ1) results in increased expression of cyclin-dependent kinase inhibitor 1C (Cdkn1c (show CDKN1C Antibodies)) only when the mutation is on the paternal allele.

  3. S3 mutations in KCNQ1 cause diverse kinetic defects in I(Ks), affecting opening and closing properties, and can account for LQT1 (show ARFGAP1 Antibodies) phenotypes.

  4. Characterization of the imprinted Kcnq1 domain which contains a differentially methylated region in intron 11 of Kcnq1.

  5. KCNQ1, KCNE2 (show KCNE2 Antibodies), and SMIT1 (show SLC5A3 Antibodies) form reciprocally regulating complexes that affect neuronal excitability.

  6. low expression of KCNQ1 expression was significantly associated with poor overall survival.

  7. Which participates in the allelic repression of Kcnq1.

  8. H(+)-K(+)-ATPase/KCNQ1 reside in independent intracytoplasmic membrane compartments, or membrane domains, and upon activation of parietal cells, both membrane proteins are transported, possibly via Rab11-positive recycling endosomes, to apical membranes.

  9. our studies reveal regulatory mechanisms within the Kcnq1 imprinted domain that operate exclusively in the heart on Kcnq1 a gene crucial for heart development and function.

  10. KCNE2 (show KCNE2 Antibodies) influences blood-CSF (show CSF2 Antibodies) anion flux by regulating KCNQ1 and KCNA3 (show KCNA3 Antibodies) in the choroid plexus epithelium.

Guinea Pig Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) interaction partners

KCNQ1 Antigen Profile

Protein Summary

This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with KCNQ1

  • KCNQ potassium channel (KCNQ) antibody
  • potassium voltage-gated channel, KQT-like subfamily, member 1 (KCNQ1) antibody
  • potassium voltage-gated channel, KQT-like subfamily, member 1 (kcnq1) antibody
  • voltage gated potassium channel subunit (kcnq1) antibody
  • KvLQT1 voltage-gated delayed rectifier potassium channel (KVLQT1) antibody
  • potassium voltage-gated channel subfamily KQT member 1-like (LOC100626134) antibody
  • potassium voltage-gated channel, KQT-like subfamily, member 1 (Kcnq1) antibody
  • potassium voltage-gated channel, subfamily Q, member 1 (Kcnq1) antibody
  • ATFB1 antibody
  • ATFB3 antibody
  • AW559127 antibody
  • CG12215 antibody
  • CG12915 antibody
  • CG33135 antibody
  • dKCNQ antibody
  • Dmel\\CG33135 antibody
  • JLNS1 antibody
  • KCNA8 antibody
  • Kcna9 antibody
  • KCNQ1 antibody
  • kcnq1-A antibody
  • kqt-3 antibody
  • Kv1.9 antibody
  • Kv7.1 antibody
  • KvLQT-1 antibody
  • KvLQT1 antibody
  • LQT antibody
  • LQT1 antibody
  • RWS antibody
  • SQT2 antibody
  • WRS antibody
  • xkvlqt1 antibody
  • zgc:158384 antibody

Protein level used designations for KCNQ1

CG33135-PC , CG33135-PD , CG33135-PE , CG33135-PF , CG33135-PG , CG33135-PH , CG33135-PI , CG33135-PJ , CG33135-PK , KCNQ-PC , KCNQ-PD , KCNQ-PE , KCNQ-PF , KCNQ-PG , KCNQ-PH , KCNQ-PI , KCNQ-PJ , KCNQ-PK , KCNQ-type K[+] channel , potassium voltage-gated channel, KQT-like subfamily, member 1 , potassium channel protein KCNQ1 , potassium voltage-gated channel, subfamily Q, member 1 , voltage gated potassium channel subunit , potassium voltage-gated channel subfamily KQT member 1 , KvLQT1 voltage-gated delayed rectifier potassium channel , Potassium voltage-gated channel subfamily KQT member 1 , IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1 , kidney and cardiac voltage dependend K+ channel , slow delayed rectifier channel subunit , voltage-gated potassium channel subunit Kv7.1 , potassium channel protein (KvLQT1) , ventricular voltage-gated K+ channel pore-forming subunit KCNQ1 , KQT-like 1 , Voltage-gated potassium channel subunit Kv7.1 , potassium channel protein , IKs producing slow voltage-gated potassium channel subunit alpha xKvLQT1

GENE ID SPECIES
36071 Drosophila melanogaster
100034129 Equus caballus
100145329 Xenopus (Silurana) tropicalis
100187466 Ciona intestinalis
557498 Danio rerio
100009443 Oryctolagus cuniculus
100626134 Sus scrofa
3784 Homo sapiens
483669 Canis lupus familiaris
397326 Sus scrofa
784876 Bos taurus
84020 Rattus norvegicus
423090 Gallus gallus
101092644 Felis catus
373746 Xenopus laevis
16535 Mus musculus
100379230 Cavia porcellus
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