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anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 3 (KCNQ3) Antibodies

The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KCNQ3 3786 O43525
KCNQ3 29682  
KCNQ3 110862 Q8K3F6
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Top anti-KCNQ3 Antibodies at antibodies-online.com

Showing 10 out of 51 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of KCNQ3 Antibody (C-term) in mouse bladder tissue lysates (35ug/lane). This demonstrates the KCNQ3 antibody detected the KCNQ3 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain, using Kv7.3/KCNQ3 (Phospho-Thr246) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Mouse Rabbit Un-conjugated WB KCNQ3 Antibody (C-term) (ABIN658608) western blot analysis in mouse bladder tissue lysates (35 µg/lane). This demonstrates the KCNQ3 antibody detected the KCNQ3 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-Kcnq3 AntibodyTitration: 1.0 µg/mL  Positive Control: Mouse Heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Kv7.3/KCNQ3 (Ab-246) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Un-conjugated IHC, ELISA 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Goat Un-conjugated ELISA, WB   0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Mouse Rabbit Biotin ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

KCNQ3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
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Rat (Rattus) ,
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Mouse (Murine) ,
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Top referenced anti-KCNQ3 Antibodies

  1. Human Polyclonal KCNQ3 Primary Antibody for EIA, WB - ABIN953015 : Gómez-Posada, Etxeberría, Roura-Ferrer, Areso, Masin, Murrell-Lagnado, Villarroel: A pore residue of the KCNQ3 potassium M-channel subunit controls surface expression. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 (PubMed)
    Show all 4 references for ABIN953015

  2. Human Polyclonal KCNQ3 Primary Antibody for IHC, ELISA - ABIN1531684 : Schroeder, Kubisch, Stein, Jentsch: Moderate loss of function of cyclic-AMP-modulated KCNQ2/KCNQ3 K+ channels causes epilepsy. in Nature 1999 (PubMed)

More Antibodies against KCNQ3 Interaction Partners

Zebrafish Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 3 (KCNQ3) interaction partners

Human Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 3 (KCNQ3) interaction partners

  1. Carboxyl terminus helix C-D linker residues play a role in KCNQ3 current amplitudes by controlling the exit of the KCNQ3 channel from the endoplasmic reticulum.

  2. a structural mechanism for the gating of the Kv7.3 PM and for the site of action of RTG as a Kv7.2 (show KCNQ2 Antibodies)/Kv7.3 K(+) current activator.

  3. In bipolar disorder patients' prefrontal cortex, Kcnq3 expression was decreased, DNA methylation (show HELLS Antibodies) was decreased, and Kcnq3 mRNA was decreased compared to controls.

  4. the clinical and EEG features of this patient further on expand the phenotypic variability of KCNQ3 gene mutations

  5. Phosphorylation of KCNQ2 (show KCNQ2 Antibodies) and KCNQ3 anchor domains by protein kinase CK2 (show CSNK2A1 Antibodies) augments binding to AnkG (show ANK3 Antibodies).

  6. mutations in KCNQ3, similarly to KCNQ2 (show KCNQ2 Antibodies), can be found in patients with more severe phenotypes including intellectual disability

  7. the present results suggest that gain-of-function mutations in Kv7.2 (show KCNQ2 Antibodies)/3 currents may cause human epilepsy with a severe clinical course

  8. We described clinical, genetic, and functional data from 17 families with a diagnosis of benign familial neonatal epilepsy caused by KCNQ2 (show KCNQ2 Antibodies) or KCNQ3 mutations and we showed that some mutations lead to a reduction of Q2 channel regulation by syntaxin-1A (show STX1A Antibodies).

  9. We monitored KCNQ2/3 channel currents and translocation of PHPLCdelta1 domains as real-time indicators of PM PI(4,5)P2, and translocation of PHOSH2x2, and PHOSH1 domains as indicators of plasma membrane and Golgi PI(4)P, respectively.

  10. A medium-throughput assay reliably detects changes in the biophysical properties of three classes of KCNQ2 (show KCNQ2 Antibodies)/3 channels and peak current amplitude and therefore may serve as a reliable assay to evaluate KCNQ2 (show KCNQ2 Antibodies)/3 openers and blockers.

Mouse (Murine) Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 3 (KCNQ3) interaction partners

  1. Mechanosensitivity of Skin Down-hair mechanoeceptors is increased in Kcnq3-/- and in Kcnq2 (show KCNQ2 Antibodies)+/-/Kcnq3-/- Mutant Mice.

  2. Resilience to tinnitus is developed in mice that show a re-emergence of KCNQ2/3 channel activity and a reduction in HCN channel activity.

  3. Data show that a reduction in Kv7.2 (show KCNQ2 Antibodies)/3 channel activity is essential for tinnitus induction and for the tinnitus-specific hyperactivity.

  4. Retigabine is more effective on KCNQ3 than KCNQ2 (show KCNQ2 Antibodies), whereas ZnPy is more effective on KCNQ2 (show KCNQ2 Antibodies) with no detectable effect on KCNQ3.

  5. Results show that in the same protein complex in which PKA augments L currents, AKAP79 (show AKAP5 Antibodies)/150 directs calcineurin (show PPP3CA Antibodies) to activate NFAT (show NFATC1 Antibodies) and initiate a longer-term feedback loop that upregulates M-channel expression, countering increased neuronal excitability.

  6. This study demonistrated that kcnq3 gene expression in mouse dorsal raphe nucleus

  7. Data show that in early pregnant mouse myometrium, the relative abundance of mRNA expression was KCNQ3 > KCNQ4 (show KCNQ4 Antibodies) > KCNQ5 (show KCNQ5 Antibodies) > KCNQ1 (show KCNQ1 Antibodies) > KCNQ2 (show KCNQ2 Antibodies).

  8. These findings provide novel evidence that KCNQ2 (show KCNQ2 Antibodies)/3 channels could be an important regulator in neuronal apoptosis.

  9. This study evaluated a model of benign familial neonatal convulsions in transgenic mice with a knockin mutation for KCNQ2 (show KCNQ2 Antibodies) and KCNQ3 mutations.

  10. expression of Kcnq2 (show KCNQ2 Antibodies) is in the modiolus and organ of Corti, while Kcnq3 expression was also detected in the cochlear lateral wall and both in spiral ganglion neurons

KCNQ3 Antigen Profile

Protein Summary

The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and one of two related proteins encoded by the KCNQ2 and KCNQ5 genes, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). Two variants encoding distinct isoforms have been found.

Gene names and symbols associated with KCNQ3

  • potassium voltage-gated channel, KQT-like subfamily, member 3 (KCNQ3) antibody
  • potassium voltage-gated channel, KQT-like subfamily, member 3 (kcnq3) antibody
  • potassium voltage-gated channel, KQT-like subfamily, member 3 (Kcnq3) antibody
  • potassium voltage-gated channel, subfamily Q, member 3 (Kcnq3) antibody
  • BFNC2 antibody
  • EBN2 antibody
  • KCNQ3 antibody
  • KV7.3 antibody
  • si:ch211-66b9.3 antibody

Protein level used designations for KCNQ3

potassium voltage-gated channel, KQT-like subfamily, member 3 , potassium voltage-gated channel KQT-like protein 3 , potassium voltage-gated channel subfamily KQT member 3 , potassium channel subunit alpha KvLQT3 , potassium channel, voltage-gated, subfamily Q, member 3 , voltage-gated potassium channel subunit Kv7.3 , KQT-like 3 , potassium voltage-gated channel, subfamily Q, member 3

GENE ID SPECIES
464403 Pan troglodytes
799747 Danio rerio
100026683 Monodelphis domestica
3786 Homo sapiens
29682 Rattus norvegicus
281884 Bos taurus
110862 Mus musculus
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