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Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 5 Proteins (KCNQ5)

KCNQ5 is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. Additionally we are shipping KCNQ5 Antibodies (63) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat KCNQ5 KCNQ5 259273  
KCNQ5 56479 Q9NR82
KCNQ5 226922 Q9JK45
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Top KCNQ5 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
HOST_Wheat germ Human GST tag   10 μg Log in to see 9 Days
$405.71
Details

KCNQ5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Top referenced KCNQ5 Proteins

  1. Human KCNQ5 Protein expressed in Wheat germ - ABIN1308482 : Caminos, Vaquero, Martinez-Galan: Relationship between rat retinal degeneration and potassium channel KCNQ5 expression. in Experimental eye research 2015 (PubMed)

More Proteins for Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 5 (KCNQ5) Interaction Partners

Human Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 5 (KCNQ5) interaction partners

  1. rs9351963 in KCNQ5 is a possible predictive factor of incidence of diarrhea in cancer patients treated with irinotecan chemotherapy.

  2. suggestive loci for periodontitis: KCNQ5 on chromosome 6q13 in a Japanese population. study should contribute to further understanding of genetic factors for enhanced susceptibility to periodontitis.

  3. Kv7.1 (show KCNQ1 Proteins)/Kv7.5 form heterotetrameric channels increasing the diversity of structures which fine-tune blood vessel reactivity. The lipid raft localization of Kv7.1 (show KCNQ1 Proteins)/Kv7.5 heteromers provides efficient spatial and temporal regulation of smooth muscle function.

  4. Differential protein kinase C-dependent modulation of Kv7.4 (show KCNQ4 Proteins) and Kv7.5 subunits of vascular Kv7 channels.

  5. characterized the cell-type specific spatial organization of the kcnq5 gene locus mediated by CTCF (show CTCF Proteins) in detail using chromosome conformation capture (3C) and 3C-derived techniques

  6. The results of this study indicated that Kv7.5 contributes to the spatial regulation of KCNE3.

  7. Data show that KCNQ1 (show KCNQ1 Proteins) mRNA expression was increased and KCNQ5 decreased in the preterm preeclamptic women.

  8. While KCNE1 (show KCNE1 Proteins) slows activation and suppresses inward rectification, KCNE3 drastically inhibits KCNQ5 currents.

  9. Src associates with KCNQ2-5 subunits but phosphorylates only KCNQ3-5.

  10. In conclusion, this work demonstrates that inactivation is a key regulatory mechanism of Kv7.4 (show KCNQ4 Proteins) and Kv7.5 channels.

Mouse (Murine) Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 5 (KCNQ5) interaction partners

  1. KCNQ5 controls excitability and function of hippocampal networks through modulation of synaptic inhibition.

  2. analysis of the vestibular role of KCNQ4 (show KCNQ4 Proteins) and KCNQ5 K+ channels revealed by mouse models

  3. Data show that in early pregnant mouse myometrium, the relative abundance of mRNA expression was KCNQ3 > KCNQ4 (show KCNQ4 Proteins) > KCNQ5 > KCNQ1 (show KCNQ1 Proteins) > KCNQ2 (show KCNQ2 Proteins).

  4. Kcnq5(dn/dn (show TMC1 Proteins)) mice are viable and have normal brain morphology. However, in the CA3 (show CA3 Proteins) area of hippocampus, a region that highly expresses KCNQ5 channels, the medium and slow afterhyperpolarization currents are significantly reduced.

  5. Data show that murine KCNQ5 channels are tightly regulated by changes in extracellular Zn2+, pH, and tonicity, thus adding to the complex regulation of these channels.

  6. Murine blood vessels exhibit a distinctive expression profile of KCNQ1 (show KCNQ1 Proteins), KCNQ4 (show KCNQ4 Proteins), and KCNQ5, with 'neuronal' KCNQ4 (show KCNQ4 Proteins) dominating

  7. These data represent an exhaustive characterisation of a truncated KCNQ5 splice variant that may contribute to the native XE991-sensitive channel in murine vasculature.

  8. Results provide support for KCNQ4 (show KCNQ4 Proteins)- or KCNQ5-encoded channels having an important functional impact in the vasculature.

  9. K(v)7.4 (show KCNQ4 Proteins) and K(v)7.5 are expressed in different regions of the murine gastrointestinal tract and blockers of K(v)7 channels augment inherent contractile activity.

KCNQ5 Protein Profile

Protein Summary

This gene is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. The protein encoded by this gene yields currents that activate slowly with depolarization and can form heteromeric channels with the protein encoded by the KCNQ3 gene. Currents expressed from this protein have voltage dependences and inhibitor sensitivities in common with M-currents. They are also inhibited by M1 muscarinic receptor activation. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with KCNQ5

  • potassium voltage-gated channel, KQT-like subfamily, member 5 (KCNQ5)
  • potassium voltage-gated channel, KQT-like subfamily, member 5a (kcnq5a)
  • potassium voltage-gated channel, KQT-like subfamily, member 5 (Kcnq5)
  • potassium voltage-gated channel, subfamily Q, member 5 (Kcnq5)
  • 7730402H11 protein
  • 9230107O05Rik protein
  • AA589396 protein
  • D1Mgi1 protein
  • KCNQ5 protein
  • Kcnq5l protein
  • Kv7.5 protein
  • si:dkey-29l6.1 protein

Protein level used designations for KCNQ5

potassium voltage-gated channel, KQT-like subfamily, member 5 , potassium voltage-gated channel subfamily KQT member 5-like , potassium voltage-gated channel subfamily KQT member 5 , potassium voltage-gated channel, subfamily Q, member 5 , KQT-like 5 , potassium channel protein , potassium channel subunit alpha KvLQT5 , voltage-gated potassium channel subunit Kv7.5 , voltage-gated potassium channel type Kv7.5

GENE ID SPECIES
462817 Pan troglodytes
556841 Danio rerio
613605 Bos taurus
100411503 Callithrix jacchus
259273 Rattus norvegicus
56479 Homo sapiens
474965 Canis lupus familiaris
100328657 Oryctolagus cuniculus
226922 Mus musculus
100154391 Sus scrofa
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