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Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 3 (KCNA3) ELISA Kits

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Additionally we are shipping KCNA3 Antibodies (96) and KCNA3 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human KCNA3 KCNA3 3738 P22001
Anti-Mouse KCNA3 KCNA3 16491 P16390
Anti-Rat KCNA3 KCNA3 29731 P15384
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More ELISA Kits for KCNA3 Interaction Partners

Human Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 3 (KCNA3) interaction partners

  1. Results contribute to the characterization of leukemic B cells, as it shows that upregulation of Kv1.3 in pathologic B lymphocytes is linked to the oncogenic B-RAF (show SNRPE ELISA Kits) signaling.

  2. Data suggest that C-terminus is necessary for Kv1.3-induced cell proliferation; the mechanism involves accessibility of key docking sites at the C terminus; phosphorylation of Tyr (show TYR ELISA Kits)-447 by MAP kinase (show MAPK1 ELISA Kits) signal cascade appears crucial.

  3. concluded that Kv1.3 may stimulate macrophage migration through the activation of ERK (show EPHB2 ELISA Kits).

  4. The inhibition of Kv1.3 channels might be involved in antiproliferative and proapoptotic effects of the compounds observed in cancer cell lines expressing these channels.

  5. Kv1.3 channels modulate human vascular smooth muscle cells proliferation independently of mTOR (show FRAP1 ELISA Kits) signaling pathway.

  6. actin dynamics regulates the membrane motility of Kv1.3 channels.

  7. The increment and decrement of the basic residue number in a positively charged S4 sensor of Kv1.3 channel yields conductance-voltage relationship curves in the positive direction by approximately 31.2 mV and 2-4 mV

  8. the association between Kv1.3 and the COPII cargo adaptor subunit isoform Sec24a (show SEC24A ELISA Kits)

  9. Findings reveal that alpha-defensins are endogenous inhibitors of potassium voltage-gated channel subfamily A member 3 (Kv1.3) with distinct interaction mechanisms.

  10. JAK2 (show JAK2 ELISA Kits) participates in the signalling, regulating the voltage-gated K(+) channel (show KCND3 ELISA Kits) KCNA3.

Mouse (Murine) Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 3 (KCNA3) interaction partners

  1. Changes in Kv1.3 subcellular distribution upon EGFR (show EGFR ELISA Kits) activation were due to Kv1.3 clathrin-dependent endocytosis, which targets the Kv1.3 channels to the lysosomal degradative pathway.

  2. Kv1.3 channel serves as a negative regulator of phagocytosis in macrophages and can be a potential target in the treatment of macrophage dysfunction

  3. concluded that Kv1.3 may stimulate macrophage migration through the activation of ERK (show EPHB2 ELISA Kits).

  4. A compensatory upregulation of the potassium channels K2P3.1 and KV1.3 seems to counterbalance the deletion of K2P5.1.

  5. JAK2 (show JAK2 ELISA Kits) participates in the signalling, regulating the voltage-gated K(+) channel (show KCND3 ELISA Kits) KCNA3.

  6. Antigenic Stimulation of Kv1.3-Deficient Th Cells Gives Rise to a Population of Foxp3 (show FOXP3 ELISA Kits)-Independent T Cells with Suppressive Properties

  7. A potent and selective peptide blocker of the Kv1.3 channel: prediction from free-energy simulations and experimental confirmation

  8. Inhibition of NMDAR (show GRIN1 ELISA Kits) antagonists on the conductivity of Kv1.3 and KCa3.1 (show KCNN4 ELISA Kits) potassium channels was found.

  9. A significant increase of Kv1.3 protein levels was observed after LPS (show TLR4 ELISA Kits) challenge, an effect that was blunted by e-LXA4. Kv1.3 is required for the attenuation of NF-kappaB (show NFKB1 ELISA Kits) activity.

  10. Results indicate the potential use of Kv1.3 blockers for the treatment of obesity and insulin (show INS ELISA Kits) resistance.

KCNA3 Antigen Profile

Antigen Summary

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and activation. This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1.

Gene names and symbols associated with KCNA3

  • potassium voltage-gated channel, shaker-related subfamily, member 3 (KCNA3) antibody
  • potassium voltage-gated channel, shaker-related subfamily, member 3 (kcna3) antibody
  • potassium voltage-gated channel, shaker-related subfamily, member 3 (Kcna3) antibody
  • cKv1.1 antibody
  • HGK5 antibody
  • HLK3 antibody
  • HPCN3 antibody
  • HUKIII antibody
  • Kca1-3 antibody
  • kcna3b-a antibody
  • Kv1.3 antibody
  • Kv1.3-glyb antibody
  • Kv1.3B antibody
  • Mk-3 antibody
  • MK3 antibody
  • PCN3 antibody

Protein level used designations for KCNA3

glibenclamide-sensitive voltage-gated potassium channel , potassium voltage-gated channel subfamily A member 3 , potassium voltage-gated channel, shaker-related subfamily, member 3 , shaker-like potassium channel subunit Kv1.3B , potassium channel 3 , type n potassium channel , voltage-gated K(+) channel HuKIII , voltage-gated potassium channel protein Kv1.3 , voltage-gated potassium channel subunit Kv1.3 , MK3 , Voltage-gated potassium channel protein Kv1.3 (RGK5) (RCK3) (KV3) , potassium voltage gated channel, shaker related subfamily, member 3 , KV3 , RCK3 , RGK5 , voltage-gated potassium channel subunit Kv3 , Shaker-like voltage-gated potassium channel cKv1.1 , shaker subfamily potassium channel Kv1.3 alpha subunit , voltage-gated Kv1.3 potassium channel

GENE ID SPECIES
100328945 Oryctolagus cuniculus
373847 Xenopus laevis
3738 Homo sapiens
16491 Mus musculus
29731 Rattus norvegicus
404303 Gallus gallus
525507 Bos taurus
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