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anti-Potassium Voltage-Gated Channel, Shal-Related Subfamily, Member 3 (KCND3) Antibodies

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Additionally we are shipping Potassium Voltage-Gated Channel, Shal-Related Subfamily, Member 3 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KCND3 56543 Q9Z0V1
KCND3 3752 Q9UK17
KCND3 65195 Q62897
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Top anti-Potassium Voltage-Gated Channel, Shal-Related Subfamily, Member 3 Antibodies at antibodies-online.com

Showing 10 out of 52 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-KCND3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-KCND3 Antibody Titration: 1.25ug/mlELISA Titer: 1:12500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated WB KCND3 Antibody (N-term) (ABIN658147) western blot analysis in CEM cell line lysates (35 µg/lane). This demonstrates the KCND3 antibody detected the KCND3 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated IHC (fro), IF, IP, WB Immunohistochemistry analysis of Kv4.3 using AM20105PU-N (Clone S75-41) tested on mouse cerebellum. Neurons appear to be positive on the membrane and slightly in the cytoplasm. Positivity on the fibers as well. Negative white matter. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Mouse Rabbit Un-conjugated WB Anti- Kv4.3 antibody, Western blotting All lanes: Anti Kv4.3  at 0.5ug/ml WB: Mouse Brain Tissue Lysate at 50ug Predicted bind size: 73KD Observed bind size: 73KD 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Rabbit Un-conjugated WB KCND3 antibody used at 1.25 ug/ml to detect target protein. 100 μg Log in to see 3 to 4 Days
$388.93
Details
Human Rabbit Un-conjugated WB   100 μg Log in to see 8 to 10 Days
$493.17
Details
Xenopus laevis Mouse Un-conjugated IP, IHC, WB   100 μg Log in to see 8 to 10 Days
$551.83
Details

KCND3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)
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Human ,
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Rat (Rattus)
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Top referenced anti-Potassium Voltage-Gated Channel, Shal-Related Subfamily, Member 3 Antibodies

  1. Chicken Polyclonal KCND3 Primary Antibody for WB - ABIN2776308 : Potapova, Cohen, Doronin: Voltage-gated ion channel Kv4.3 is associated with Rap guanine nucleotide exchange factors and regulates angiotensin receptor type 1 signaling to small G-protein Rap. in The FEBS journal 2007 (PubMed)

  2. Human Polyclonal KCND3 Primary Antibody for WB - ABIN2776172 : Hatano, Ohya, Muraki, Clark, Giles, Imaizumi: Two arginines in the cytoplasmic C-terminal domain are essential for voltage-dependent regulation of A-type K+ current in the Kv4 channel subfamily. in The Journal of biological chemistry 2004 (PubMed)

More Antibodies against Potassium Voltage-Gated Channel, Shal-Related Subfamily, Member 3 Interaction Partners

Mouse (Murine) Potassium Voltage-Gated Channel, Shal-Related Subfamily, Member 3 (KCND3) interaction partners

  1. In ERaKO but not ERaKO mice, the mRNA of Kv4.3 was selectively increased... E2 negatively regulates the density of Ito through ERa, this highlights a potential role for this female hormone in modulating cardiac electrical activity.

  2. Data show that potassium channel (show KCNAB2 Antibodies) Kv4.3 outward current is presented incardiomyocyte lacking the potassium channel Kv4.2 (show KCND2 Antibodies) gene (Kv4.2 (show KCND2 Antibodies)-/-).

  3. The gain-of-function SCNA overexpressing dopamine substantia nigra neurons was in part mediated by an increase of their intrinsic pacemaker frequency caused by a redox-dependent impairment of Kv4.3

  4. The protein levels of KV4.3 and KV2.2 (show KCNB2 Antibodies) were up-regulated in the hypertrophic smooth muscle cell membrane.

  5. The experiments here demonstrate that Kv4.2 (show KCND2 Antibodies), Kv4.3 and Kv1.4 (show KCNA4 Antibodies) all contribute to the generation of potassium channels in mature cortical pyramidal (CP) neurons; these channels play distinct roles in regulating the intrinsic properties of mature CP neurons.

  6. Taken together, these data suggest that nerve injury causes an epigenetic silencing of K(v)4.3 gene mediated through transcriptional suppressor NRSF in the DRG.

  7. Kv4.3 channel alpha-subunit (show POLG Antibodies) is found to be one of the components (along with Kv4.2 (show KCND2 Antibodies) and Kv1.4 (show KCNA4 Antibodies)) that propagates the voltage-gated potassium current in pyramidal cortical neurons.

  8. Ativation of AT1 (show SLC33A1 Antibodies) receptors by Angioteinsin II or stretch specifically destabilizes cardiac myocyte Kv4.3 channel mRNA by activating NADPH oxidase (show NOX1 Antibodies).

  9. The results show that Kv4.3 is concentrated in layer 1, the bottom of layer 2/3, and in layers 4 and 5/6.

  10. The results presented here suggest that, in contrast with Kv4.2 (show KCND2 Antibodies), Kv4.3 is not required for the generation of functional mouse ventricular I(to,f) channels.

Human Potassium Voltage-Gated Channel, Shal-Related Subfamily, Member 3 (KCND3) interaction partners

  1. mutations cause a gainoffunction of KV4.3/KChIP2encoded channels by increasing membrane protein expression and slowing channel inactivation.

  2. Altered Kv4.3 channel localization and/or functioning resulting from SCA19/22 mutations may lead to Purkinje cell loss, neurodegeneration and ataxia (show USP14 Antibodies).

  3. the interaction of DPP10a, expressed in human atrium, with Kv4.3 channels generates a sustained current component of Ito, which may affect late repolarization phase of atrial action potentials.

  4. Kv4.3 K(+) channel (show KCNC4 Antibodies) is involved in heart hypertrophy/heart failure independently of its electric function.[review]

  5. Demonstrate SEMA3A (show SEMA3A Antibodies) as a naturally occurring protein that selectively inhibits Kv4.3 and SEMA3A (show SEMA3A Antibodies) as a possible Brugada syndrome susceptibility gene through a Kv4.3 gain-of-function mechanism.

  6. maps to chromosome 1p21-q21 and identification in Dutch autosomal dominant cerebellar ataxia (show USP14 Antibodies) family

  7. These results indicate that Kv4.3 is likely the target of discrepin and highlight the importance of the basic residue K13 (show KCNG1 Antibodies), located in the alpha-helix of the toxin, for current blockage.

  8. findings indicate mutations in KCND3 are not a common cause of disease among rarer types of European cerebellar ataxia (show USP14 Antibodies); however 2 variants were identified in the SCA cases: p.L450F and p.P614S; mutations in KCND3 can cause 2 allelic disorders, SCA19/22 and Brugada syndrome which may co-occur

  9. Report a KV4.3 gain-of-function mutation in early-onset persistent lone atrial fibrillation.

  10. expression of the sodium (SCN5A (show SCN5A Antibodies)) and potassium (KCND3) channels as well as the fibrosis content in the ventricles of heart failure and of non-diseased hearts under different post-mortem intervals

Xenopus laevis Potassium Voltage-Gated Channel, Shal-Related Subfamily, Member 3 (KCND3) interaction partners

  1. biophysical 11-state Markov model of Kv4.3 gating incorporating a direct transition from the open-inactivated state to the closed-inactivated state

  2. Our data demonstrate isoform-specific regulation of closed-state inactivation by protein kinase C (show PKC Antibodies) in Kv4.3

Potassium Voltage-Gated Channel, Shal-Related Subfamily, Member 3 (KCND3) Antigen Profile

Protein Summary

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene.

Gene names and symbols associated with KCND3

  • potassium voltage-gated channel, Shal-related subfamily, member 3 (KCND3) antibody
  • potassium voltage-gated channel, Shal-related subfamily, member 3 (kcnd3) antibody
  • potassium voltage-gated channel, Shal-related family, member 3 (Kcnd3) antibody
  • potassium voltage-gated channel, Shal-related subfamily, member 3 (Kcnd3) antibody
  • AW045978 antibody
  • K(v)4.3 antibody
  • KCND3 antibody
  • kcnd3-A antibody
  • KCND3L antibody
  • KCND3S antibody
  • Kncd3 antibody
  • KSHIVB antibody
  • KV4.3 antibody
  • wu:fi06g01 antibody
  • xKv4.3 antibody
  • zgc:55306 antibody

Protein level used designations for KCND3

potassium voltage-gated channel, Shal-related subfamily, member 3 , potassium voltage-gated channel subfamily D member 3-like , potassium voltage-gated channel subfamily D member 3 , potassium voltage-gated channel, Shal-related family, member 3 , zShal3 , potassium channel Kv4.3 , potassium voltage-gated channel Shal-related subfamily member 3 , potassium channel Kv4.3L , potassium channel Kv4.3M , voltage-gated potassium channel subunit Kv4.3 , potassium ionic channel Kv4.3 , sha1-related potassium channel Kv4.3 , voltage-gated K+ channel , potassium voltage gated channel, Shal-related family, member 3

GENE ID SPECIES
744303 Pan troglodytes
100030530 Monodelphis domestica
100058973 Equus caballus
100076092 Ornithorhynchus anatinus
100394264 Callithrix jacchus
100431693 Pongo abelii
100481914 Ailuropoda melanoleuca
100556636 Anolis carolinensis
100606231 Nomascus leucogenys
327415 Danio rerio
403758 Canis lupus familiaris
539739 Bos taurus
641437 Macaca mulatta
100125015 Xenopus (Silurana) tropicalis
56543 Mus musculus
3752 Homo sapiens
100037946 Sus scrofa
100009472 Oryctolagus cuniculus
65195 Rattus norvegicus
101115919 Ovis aries
378574 Xenopus laevis
374228 Gallus gallus
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