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Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 1 (KCNC1) ELISA Kits

The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Additionally we are shipping Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 1 Antibodies (117) and Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 1 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse KCNC1 KCNC1 16502 P15388
Anti-Rat KCNC1 KCNC1 25327 P25122
Anti-Human KCNC1 KCNC1 3746 P48547
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More ELISA Kits for Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 1 Interaction Partners

Mouse (Murine) Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 1 (KCNC1) interaction partners

  1. Kv3.1 channels stimulate adult neural precursor cell proliferation and neuronal differentiation.

  2. The resting (closed) Kv3.1 channel conformation forms the high-affinity state for gambierol.

  3. high-affinity multimeric binding between the Kv3.1 T1 domain and KIF5B (show KIF5B ELISA Kits) requires three basic residues in the KIF5B (show KIF5B ELISA Kits) tail. Kv3.1 T1 competes with the motor domain and microtubules, but not with kinesin light chain 1 (KLC1 (show KLC1 ELISA Kits)), for binding to the KIF5B (show KIF5B ELISA Kits) tail.

  4. Although all Kv3 (show KCNA3 ELISA Kits) transcripts were significantly expressed at embryonic age in whole brain extracts, only Kv3.1, Kv3.2 and Kv3.4 su (show KCNC2 ELISA Kits)bunit prot (show KCNC4 ELISA Kits)eins were present, suggesting a novel role for Kv3 channels at this developmental stage.

  5. Block of Kv3.1 channels hinders spike repolarization and severely depresses evoked fast firing in deep cerebellar nuclear neurons.

  6. Mice lacking both Kcnc1 and Kcnc2 (show KCNC2 ELISA Kits) genes fail to express the Kv3.1 and Kv3.2 (show KCNC2 ELISA Kits) channels in in the suprachiasmatic nucleus.

  7. These results provide evidence that acoustically driven auditory activity can selectively regulate high-threshold potassium currents in the MNTB of normal hearing mice, likely due to an increased membrane expression of Kv3.1b channels.

  8. As Kcnc1, but not Kcnc3 (show KCNC3 ELISA Kits), alleles are lost, mutant mice exhibit increasing gait ataxia (show USP14 ELISA Kits) accompanied by spike broadening and deceleration in deep cerebellar nuclei. neurons.

  9. interaction with CALP/KCHIP4 (show KCNIP4 ELISA Kits)

  10. NCS-1 (show NCS1 ELISA Kits) is an accessory subunit of Kv4-encoded I(to,f) channels that functions to regulate I(to,f) density in the mammalian myocardium.

Human Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 1 (KCNC1) interaction partners

  1. KCNC1 produces a resurgent current during repolarization, ensuring enough repolarizing power to terminate each action potential. The current results from a combination of steep voltage-dependent gating kinetics and ultra-fast voltage-sensor relaxation.

  2. A recurrent KCNC1 de novo mutation, c.959G>A (p.Arg320His), is a new major cause for progressive myoclonus epilepsy. It has a dominant-negative loss-of-function effect.

  3. Describes two rat isoforms of Kv3.1, alpha is the longer one and beta is the shorter one

  4. KChIP4a (show KCNIP4 ELISA Kits) suppresses A-type Kv4 current via ER retention and enhancement of Kv4 closed-state inactivation.

  5. Although all KV3 (show KCNA3 ELISA Kits) subunit transcripts are significantly expressed at embryonic age in whole mouse brain extracts, only KV3.1, KV3.2 (show KCNC2 ELISA Kits) and KV3.4 (show KCNC4 ELISA Kits) subunit transgenic proteins are present.

  6. demonstrated that glycosylation was necessary for both DPP10 trafficking to the cell surface and functional interaction with Kv4 channels

  7. Kv3.1 channels are transported into axons by binding to kinesin I.

  8. In the absence of potassium ion, significant N-methyl-D-glucamine (NMDG)-positive currents could be recorded from human embryonic kidney cells expressing Kv3.1 or Kv3.2b channels and Kv1.5 (show KCNA5 ELISA Kits) Arg487Tyr/Val, but not wild-type channels.

Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 1 (KCNC1) Antigen Profile

Antigen Summary

The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to one of these subfamilies, namely the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. Multiple transcript variants encoding different isoforms have been inferred for this gene based on orthologous loci.

Gene names and symbols associated with KCNC1

  • potassium voltage-gated channel, Shaw-related subfamily, member 1 (KCNC1) antibody
  • potassium voltage-gated channel, Shaw-related subfamily, member 1 (kcnc1) antibody
  • potassium voltage gated channel, Shaw-related subfamily, member 1 (Kcnc1) antibody
  • potassium voltage-gated channel, Shaw-related subfamily, member 1a (kcnc1a) antibody
  • C230009H10Rik antibody
  • KCNC2 antibody
  • Kcr2-1 antibody
  • KShIIIB antibody
  • KV3.1 antibody
  • Kv4 antibody
  • NGK2 antibody
  • NGK2-KV4 antibody
  • Shaw antibody
  • zgc:194940 antibody
  • zgc:194950 antibody

Protein level used designations for KCNC1

potassium voltage-gated channel, Shaw-related subfamily, member 1 , potassium channel Kv3.1 , potassium voltage-gated channel subfamily C member 1 , voltage-gated potassium channel subunit Kv3.1 , voltage-gated potassium channel subunit Kv4 , NGK2 , RAW2 , potassium channel gene 1 , voltage-gated potassium channel protein KV3.1 , Shaw-related voltage-gated potassium channel protein 1 , potassium channel , voltage-gated potassium channel KCNC1 , kcnc1 , voltage-gated potassium channel Kv3.1a

GENE ID SPECIES
466452 Pan troglodytes
100020061 Monodelphis domestica
100056567 Equus caballus
100144433 Taeniopygia guttata
100144936 Xenopus (Silurana) tropicalis
16502 Mus musculus
25327 Rattus norvegicus
3746 Homo sapiens
423076 Gallus gallus
403705 Canis lupus familiaris
541459 Bos taurus
100008968 Oryctolagus cuniculus
565419 Danio rerio
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