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Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 1 Proteins (KCNC1)

The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Additionally we are shipping Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 1 Antibodies (130) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KCNC1 16502 P15388
Rat KCNC1 KCNC1 25327 P25122
KCNC1 3746 P48547
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Top Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 1 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details

KCNC1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
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Human ,
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More Proteins for Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 1 (KCNC1) Interaction Partners

Mouse (Murine) Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 1 (KCNC1) interaction partners

  1. Kv3.1 channels stimulate adult neural precursor cell proliferation and neuronal differentiation.

  2. The resting (closed) Kv3.1 channel conformation forms the high-affinity state for gambierol.

  3. high-affinity multimeric binding between the Kv3.1 T1 domain and KIF5B requires three basic residues in the KIF5B tail. Kv3.1 T1 competes with the motor domain and microtubules, but not with kinesin light chain 1 (KLC1 (show KLC1 Proteins)), for binding to the KIF5B tail.

  4. Although all Kv3 (show KCNA3 Proteins) transcripts were significantly expressed at embryonic age in whole brain extracts, only Kv3.1, Kv3.2 and Kv3.4 su (show KCNC2 Proteins)bunit prot (show KCNC4 Proteins)eins were present, suggesting a novel role for Kv3 channels at this developmental stage.

  5. Block of Kv3.1 channels hinders spike repolarization and severely depresses evoked fast firing in deep cerebellar nuclear neurons.

  6. Mice lacking both Kcnc1 and Kcnc2 (show KCNC2 Proteins) genes fail to express the Kv3.1 and Kv3.2 (show KCNC2 Proteins) channels in in the suprachiasmatic nucleus.

  7. These results provide evidence that acoustically driven auditory activity can selectively regulate high-threshold potassium currents in the MNTB of normal hearing mice, likely due to an increased membrane expression of Kv3.1b channels.

  8. As Kcnc1, but not Kcnc3 (show KCNC3 Proteins), alleles are lost, mutant mice exhibit increasing gait ataxia (show USP14 Proteins) accompanied by spike broadening and deceleration in deep cerebellar nuclei. neurons.

  9. interaction with CALP/KCHIP4 (show KCNIP4 Proteins)

  10. NCS-1 (show NCS1 Proteins) is an accessory subunit of Kv4-encoded I(to,f) channels that functions to regulate I(to,f) density in the mammalian myocardium.

Human Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 1 (KCNC1) interaction partners

  1. KCNC1 produces a resurgent current during repolarization, ensuring enough repolarizing power to terminate each action potential. The current results from a combination of steep voltage-dependent gating kinetics and ultra-fast voltage-sensor relaxation.

  2. A recurrent KCNC1 de novo mutation, c.959G>A (p.Arg320His), is a new major cause for progressive myoclonus epilepsy. It has a dominant-negative loss-of-function effect.

  3. Describes two rat isoforms of Kv3.1, alpha is the longer one and beta is the shorter one

  4. KChIP4a (show KCNIP4 Proteins) suppresses A-type Kv4 current via ER retention and enhancement of Kv4 closed-state inactivation.

  5. Although all KV3 (show KCNA3 Proteins) subunit transcripts are significantly expressed at embryonic age in whole mouse brain extracts, only KV3.1, KV3.2 (show KCNC2 Proteins) and KV3.4 (show KCNC4 Proteins) subunit transgenic proteins are present.

  6. demonstrated that glycosylation was necessary for both DPP10 trafficking to the cell surface and functional interaction with Kv4 channels

  7. Kv3.1 channels are transported into axons by binding to kinesin I.

  8. In the absence of potassium ion, significant N-methyl-D-glucamine (NMDG)-positive currents could be recorded from human embryonic kidney cells expressing Kv3.1 or Kv3.2b channels and Kv1.5 (show KCNA5 Proteins) Arg487Tyr/Val, but not wild-type channels.

Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 1 (KCNC1) Protein Profile

Protein Summary

The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to one of these subfamilies, namely the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. Multiple transcript variants encoding different isoforms have been inferred for this gene based on orthologous loci.

Gene names and symbols associated with KCNC1

  • potassium voltage-gated channel, Shaw-related subfamily, member 1 (KCNC1)
  • potassium voltage-gated channel, Shaw-related subfamily, member 1 (kcnc1)
  • potassium voltage gated channel, Shaw-related subfamily, member 1 (Kcnc1)
  • potassium voltage-gated channel, Shaw-related subfamily, member 1a (kcnc1a)
  • C230009H10Rik protein
  • KCNC2 protein
  • Kcr2-1 protein
  • KShIIIB protein
  • KV3.1 protein
  • Kv4 protein
  • NGK2 protein
  • NGK2-KV4 protein
  • Shaw protein
  • zgc:194940 protein
  • zgc:194950 protein

Protein level used designations for KCNC1

potassium voltage-gated channel, Shaw-related subfamily, member 1 , potassium channel Kv3.1 , potassium voltage-gated channel subfamily C member 1 , voltage-gated potassium channel subunit Kv3.1 , voltage-gated potassium channel subunit Kv4 , NGK2 , RAW2 , potassium channel gene 1 , voltage-gated potassium channel protein KV3.1 , Shaw-related voltage-gated potassium channel protein 1 , potassium channel , voltage-gated potassium channel KCNC1 , kcnc1 , voltage-gated potassium channel Kv3.1a

GENE ID SPECIES
466452 Pan troglodytes
100020061 Monodelphis domestica
100056567 Equus caballus
100144433 Taeniopygia guttata
100144936 Xenopus (Silurana) tropicalis
16502 Mus musculus
25327 Rattus norvegicus
3746 Homo sapiens
423076 Gallus gallus
403705 Canis lupus familiaris
541459 Bos taurus
100008968 Oryctolagus cuniculus
565419 Danio rerio
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