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Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 2 Proteins (KCNC2)

The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Additionally we are shipping KCNC2 Antibodies (65) and KCNC2 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KCNC2 268345  
Rat KCNC2 KCNC2 246153 P22462
KCNC2 3747 Q96PR1
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Top KCNC2 Proteins at antibodies-online.com

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details

KCNC2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
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Human ,
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More Proteins for Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 2 (KCNC2) Interaction Partners

Mouse (Murine) Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 2 (KCNC2) interaction partners

  1. Although all Kv3 (show KCNA3 Proteins) transcripts were significantly expressed in embryonic age in whole brain extracts, only Kv3.1, Kv3.2 (show KCNC1 Proteins) and Kv3.4 subuni (show KCNC4 Proteins)t proteins aree present, suggesting a novel role for Kv3 channels at this developmental stage.

  2. Mice lacking both Kcnc1 (show KCNC1 Proteins) and Kcnc2 genes fail to express the Kv3.1 (show KCNC1 Proteins) and Kv3.2 channels in in the suprachiasmatic nucleus.

  3. Developmental expression of potassium-channel subunit (show KCNT1 Proteins) Kv3.2 within subpopulations of mouse hippocampal inhibitory interneurons.

  4. Starburst amacrine cells have large outward currents which are mediated in part by the Kv3.2 channel.

  5. Kv3.2 expression became detectable in the lumbar cord from postnatal day 12, and increased steadily until reaching an adult level at postnatal day 28. In contrast to the Kv3.1b results, Kv3.2 was not expressed in Renshaw cells.

  6. Kv3.2, Kv1 (show KCNA5 Proteins), SK potassium and N-type calcium channels strongly regulate thalamic relay neuron sensory transmission and that each channel subtype controls a different stimulus-response curve property.

Human Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 2 (KCNC2) interaction partners

  1. Kv3.2 is not different in distribution or in level between normal and schizophrenia cases, nor influenced by antipsychotic drugs, in any brain region tested

  2. This family's complex phenotype is associated with a new chromosomal deletion, which suggests potential roles for the two genes, KCNC2 and ATXN7L3B, in human neurological disease.

  3. Although all KV3 (show KCNA3 Proteins) subunit transcripts are significantly expressed at embryonic age in whole brain extracts, only KV3.1 (show KCNC1 Proteins), KV3.2 and KV3.4 (show KCNC4 Proteins) subunit transgenic proteins are present.

  4. In the absence of potassium ion, significant N-methyl-D-glucamine (NMDG)-positive currents could be recorded from human embryonic kidney cells expressing Kv3.1 (show KCNC1 Proteins) or Kv3.2b channels and Kv1.5 (show KCNA5 Proteins) Arg487Tyr/Val, but not wild-type channels.

KCNC2 Protein Profile

Protein Summary

The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to one of these subfamilies, namely the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. Several transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with KCNC2

  • potassium voltage-gated channel, Shaw-related subfamily, member 2 (KCNC2)
  • Shaw-related voltage-gated potassium channel protein 2 (KCNC2)
  • potassium voltage-gated channel, Shaw-related subfamily, member 2 (kcnc2)
  • potassium voltage gated channel, Shaw-related subfamily, member 2 (Kcnc2)
  • AW047325 protein
  • B230117I07 protein
  • KCNC2 protein
  • KShIIIA protein
  • KV3.2 protein
  • zgc:162956 protein

Protein level used designations for KCNC2

potassium voltage-gated channel, Shaw-related subfamily, member 2 , potassium voltage-gated channel subfamily C member 2 , Shaw-related voltage-gated potassium channel protein 2 , potassium voltage-gated channel subfamily C member 2-like , voltage-gated potassium channel Kv3.2 , voltage-gated potassium channel subunit Kv3.2

GENE ID SPECIES
481168 Canis lupus familiaris
539913 Bos taurus
692079 Macaca mulatta
743998 Pan troglodytes
772061 Gallus gallus
100012362 Monodelphis domestica
100037377 Danio rerio
100050104 Equus caballus
100153996 Sus scrofa
100345412 Oryctolagus cuniculus
100405757 Callithrix jacchus
100430906 Macaca mulatta
100431553 Pongo abelii
100489216 Xenopus (Silurana) tropicalis
100550726 Meleagris gallopavo
268345 Mus musculus
246153 Rattus norvegicus
3747 Homo sapiens
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