Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 3 (KCNQ3) ELISA Kits

The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. Additionally we are shipping KCNQ3 Antibodies (52) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human KCNQ3 KCNQ3 3786 O43525
Anti-Rat KCNQ3 KCNQ3 29682  
Anti-Mouse KCNQ3 KCNQ3 110862 Q8K3F6
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More ELISA Kits for KCNQ3 Interaction Partners

Zebrafish Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 3 (KCNQ3) interaction partners

Human Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 3 (KCNQ3) interaction partners

  1. In the present work, a pharmacophore-based 3D-QSAR model was generated for a series of N-pyridyl and pyrimidine benzamides possessing KCNQ2 (show KCNQ2 ELISA Kits)/Q3 opening activity. The pharmacophore model generated contains one hydrogen bond donor (D), one hydrophobic (H), and two aromatic rings (R). They are the crucial molecular write-up detailing predicted binding efficacy of high affinity and low affinity ligands for KCNQ2 (show KCNQ2 ELISA Kits)/Q3 opening a

  2. Tannic acid activates Kv7.4 (show KCNQ4 ELISA Kits) and Kv7.3/7.5 K(+) channels resulting in vasodilation.

  3. USP36 (show USP36 ELISA Kits) actions extend beyond TrkA (show NTRK1 ELISA Kits) because the presence of USP36 (show USP36 ELISA Kits) interferes with Nedd4-2-dependent Kv7.2 (show KCNQ2 ELISA Kits)/3 channel regulation.

  4. Carboxyl terminus helix C-D linker residues play a role in KCNQ3 current amplitudes by controlling the exit of the KCNQ3 channel from the endoplasmic reticulum.

  5. a structural mechanism for the gating of the Kv7.3 PM and for the site of action of RTG as a Kv7.2 (show KCNQ2 ELISA Kits)/Kv7.3 K(+) current activator.

  6. In bipolar disorder patients' prefrontal cortex, Kcnq3 expression was decreased, DNA methylation (show HELLS ELISA Kits) was decreased, and Kcnq3 mRNA was decreased compared to controls.

  7. the clinical and EEG features of this patient further on expand the phenotypic variability of KCNQ3 gene mutations

  8. Phosphorylation of KCNQ2 (show KCNQ2 ELISA Kits) and KCNQ3 anchor domains by protein kinase CK2 (show CSNK2A1 ELISA Kits) augments binding to AnkG (show ANK3 ELISA Kits).

  9. mutations in KCNQ3, similarly to KCNQ2 (show KCNQ2 ELISA Kits), can be found in patients with more severe phenotypes including intellectual disability

  10. the present results suggest that gain-of-function mutations in Kv7.2 (show KCNQ2 ELISA Kits)/3 currents may cause human epilepsy with a severe clinical course

Mouse (Murine) Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 3 (KCNQ3) interaction partners

  1. USP36 (show USP36 ELISA Kits) actions extend beyond TrkA (show NTRK1 ELISA Kits) because the presence of USP36 (show USP36 ELISA Kits) interferes with Nedd4-2-dependent Kv7.2 (show KCNQ2 ELISA Kits)/3 channel regulation.

  2. KCNQ3 plays an essential role in maintaining the slow afterhyperpolarization under low phosphatidylinositol diphosphate conditions.

  3. Mechanosensitivity of Skin Down-hair mechanoeceptors is increased in Kcnq3-/- and in Kcnq2 (show KCNQ2 ELISA Kits)+/-/Kcnq3-/- Mutant Mice.

  4. Resilience to tinnitus is developed in mice that show a re-emergence of KCNQ2/3 channel activity and a reduction in HCN channel activity.

  5. Data show that a reduction in Kv7.2 (show KCNQ2 ELISA Kits)/3 channel activity is essential for tinnitus induction and for the tinnitus-specific hyperactivity.

  6. Retigabine is more effective on KCNQ3 than KCNQ2 (show KCNQ2 ELISA Kits), whereas ZnPy is more effective on KCNQ2 (show KCNQ2 ELISA Kits) with no detectable effect on KCNQ3.

  7. Results show that in the same protein complex in which PKA augments L currents, AKAP79 (show AKAP5 ELISA Kits)/150 directs calcineurin to activate NFAT (show NFATC1 ELISA Kits) and initiate a longer-term feedback loop that upregulates M-channel expression, countering increased neuronal excitability.

  8. This study demonistrated that kcnq3 gene expression in mouse dorsal raphe nucleus

  9. Data show that in early pregnant mouse myometrium, the relative abundance of mRNA expression was KCNQ3 > KCNQ4 (show KCNQ4 ELISA Kits) > KCNQ5 (show KCNQ5 ELISA Kits) > KCNQ1 (show KCNQ1 ELISA Kits) > KCNQ2 (show KCNQ2 ELISA Kits).

  10. These findings provide novel evidence that KCNQ2 (show KCNQ2 ELISA Kits)/3 channels could be an important regulator in neuronal apoptosis.

KCNQ3 Antigen Profile

Antigen Summary

The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and one of two related proteins encoded by the KCNQ2 and KCNQ5 genes, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). Two variants encoding distinct isoforms have been found.

Gene names and symbols associated with KCNQ3

  • potassium voltage-gated channel subfamily Q member 3 (KCNQ3) antibody
  • potassium voltage-gated channel, KQT-like subfamily, member 3 (kcnq3) antibody
  • potassium voltage-gated channel subfamily Q member 3 (Kcnq3) antibody
  • potassium voltage-gated channel, subfamily Q, member 3 (Kcnq3) antibody
  • BFNC2 antibody
  • EBN2 antibody
  • KCNQ3 antibody
  • KV7.3 antibody
  • si:ch211-66b9.3 antibody

Protein level used designations for KCNQ3

potassium voltage-gated channel, KQT-like subfamily, member 3 , potassium voltage-gated channel KQT-like protein 3 , potassium voltage-gated channel subfamily KQT member 3 , potassium channel subunit alpha KvLQT3 , potassium channel, voltage-gated, subfamily Q, member 3 , voltage-gated potassium channel subunit Kv7.3 , KQT-like 3 , potassium voltage-gated channel, subfamily Q, member 3

GENE ID SPECIES
464403 Pan troglodytes
799747 Danio rerio
100026683 Monodelphis domestica
3786 Homo sapiens
29682 Rattus norvegicus
281884 Bos taurus
110862 Mus musculus
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