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anti-Pre-B Lymphocyte 1 (VPREB1) Antibodies

The protein encoded by VPREB1 belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. Additionally we are shipping Pre-B Lymphocyte 1 Proteins (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
VPREB1 7441 P12018
VPREB1 303782  
VPREB1 22362 P13372
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Top anti-Pre-B Lymphocyte 1 Antibodies at antibodies-online.com

Showing 10 out of 41 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-VPREB1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rat Un-conjugated FACS, IP, ELISA, WB Differential expression of CD179a (VpreB) on B lymphomas. The 70Z/3 (sIg- pre-B lymphoblast, first panel) and A20 (sIg+ B lymphoma, second panel) cell lines were stained with either purified rat IgG2a, kappa isotype control mAb R35-95 (solid histograms) or purified mAb R3/VpreB (open histograms), followed by biotinylated anti-rat IgG2a mAb RG7/1.30, then Streptavidin-PE. Flow cytometry was performed on a BD FACSCalibur™ flow cytometry system. Differential expression of CD179a (VpreB) on B lymphomas. The 70Z/3 (sIg- pre-B lymphoblast, first panel) and A20 (sIg+ B lymphoma, second panel) cell lines were stained with either purified rat IgG2a, kappa isotype control mAb R35-95 (solid histograms) or purified mAb R3/VpreB (open histograms), followed by biotinylated anti-rat IgG2a mAb RG7/1.30, then Streptavidin-PE. Flow cytometry was performed on a BD FACSCalibur™ flow cytometry system. 0.1 mg Log in to see 5 to 6 Days
$275.29
Details
Mouse Rat PE FACS, IF 100 μg Log in to see 10 to 12 Days
$211.97
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse PE FACS, IHC, ELISA, WB 100 Tests Log in to see 10 to 12 Days
$304.37
Details
Human Rabbit Un-conjugated WB SIRPB1 Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the SIRPB1 antibody detected the SIRPB1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Mouse Rat Un-conjugated ICFC 100 μg Log in to see 10 to 12 Days
$119.57
Details
Human Mouse Un-conjugated FACS 100 μg Log in to see 10 to 12 Days
$244.59
Details
Human Rabbit Un-conjugated WB VPREB1 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details

VPREB1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Pre-B Lymphocyte 1 Antibodies

  1. Mouse (Murine) Monoclonal VPREB1 Primary Antibody for FACS, IP - ABIN967587 : Mårtensson, Ceredig: Review article: role of the surrogate light chain and the pre-B-cell receptor in mouse B-cell development. in Immunology 2000 (PubMed)
    Show all 6 references for ABIN967587

  2. Human Monoclonal VPREB1 Primary Antibody for FACS, IHC - ABIN2663102 : Zhang, Srivastava, Lu: The pre-B cell receptor and its function during B cell development. in Cellular & molecular immunology 2005 (PubMed)
    Show all 4 references for ABIN2663102

  3. Mouse (Murine) Monoclonal VPREB1 Primary Antibody for ICFC - ABIN2664300 : Stephan, Elgavish, Karasuyama, Kubagawa, Cooper: Analysis of VpreB expression during B lineage differentiation in lambda5-deficient mice. in Journal of immunology (Baltimore, Md. : 1950) 2001 (PubMed)
    Show all 3 references for ABIN2664300

  4. Human Monoclonal VPREB1 Primary Antibody for FACS - ABIN2664299 : Tsuganezawa, Kiyokawa, Matsuo, Kitamura, Toyama-Sorimachi, Kuida, Fujimoto, Karasuyama: Flow cytometric diagnosis of the cell lineage and developmental stage of acute lymphoblastic leukemia by novel monoclonal antibodies specific to human pre-B-cell receptor. in Blood 1999 (PubMed)
    Show all 3 references for ABIN2664299

  5. Mouse (Murine) Monoclonal VPREB1 Primary Antibody for FACS, IF - ABIN2662481 : Wang, Stephan, Scheffold, Kunkel, Karasuyama, Radbruch, Cooper: Differential surrogate light chain expression governs B-cell differentiation. in Blood 2002 (PubMed)
    Show all 3 references for ABIN2662481

  6. Cow (Bovine) Polyclonal VPREB1 Primary Antibody for WB - ABIN2775363 : Rossi, Espeli, Schiff, Gauthier: Clustering of pre-B cell integrins induces galectin-1-dependent pre-B cell receptor relocalization and activation. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)

More Antibodies against Pre-B Lymphocyte 1 Interaction Partners

Human Pre-B Lymphocyte 1 (VPREB1) interaction partners

  1. VPREB1 focal deletions are common in B-ALL and occur independent of V(D)J light chain recombination. Focal deletions of VPREB1 correlate with decreased expression levels and high-risk patients with focal deletions tend to have poorer overall survival

  2. The proportion of the individuals with <2 copies of the VPREB1 gene was significantly higher in the patient group than that in the controls, while that of the individuals with >2 copies was lower in the patient group than that in the controls.

  3. The 5' region of the VpreB gene contains a promoter which displays higher relative activity in preB (show PREB Antibodies) cells compared with cells at other stages or from other lineages.

  4. Pre-B cell integrins and their stromal cell ligands together with the pre-B cell receptor and galectin-1 (show LGALS1 Antibodies) form a homogeneous lattice at the contact area between bone marrow pre-B and stromal cells.

Mouse (Murine) Pre-B Lymphocyte 1 (VPREB1) interaction partners

  1. Data show no autoantibody production was detectable in surrogate light chain (SLC (show CCL21A Antibodies)) components VpreB/CD179a and lambda5/CD179b (show IGLL1 Antibodies) transgenic mice.

  2. VpreB probes the fitness of newly generated VH domains of IgH chains for later pairing with IgL chains, and its non-Ig part fixes the preBCRs on the surface.

  3. Mice triply deficient for VpreB1 show B cell developmental defects but functional allelic exclusion of the IgH locus.

  4. To identify the sequences that regulate lambda5 and VpreB1 (show IGLL1 Antibodies) expression during B cell development, the DNaseI (show DNASE1 Antibodies) hypersensitive sites in the lambda5-VpreB1 (show IGLL1 Antibodies) functional domain were mapped.

  5. Multiple receptor-dependent mechanisms operating at all stages of B cell development limit the contribution of B cells with Dmu (show SCN8A Antibodies) heavy chain alleles to the repertoire.

Pre-B Lymphocyte 1 (VPREB1) Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation.

Gene names and symbols associated with VPREB1

  • pre-B lymphocyte 1 (VPREB1) antibody
  • immunoglobulin omega chain-like (VPREB1) antibody
  • pre-B lymphocyte 1 (Vpreb1) antibody
  • pre-B lymphocyte gene 1 (Vpreb1) antibody
  • CD179a antibody
  • IGI antibody
  • IGVPB antibody
  • VpreB antibody
  • Vpreb-1 antibody

Protein level used designations for VPREB1

pre-B lymphocyte 1 , pre-B lymphocyte gene 1 , CD179 antigen-like family member A , CD179a , immunoglobulin iota chain , v(pre)B protein , Immunoglobulin lambda Vpreb1 chain

GENE ID SPECIES
458686 Pan troglodytes
698810 Macaca mulatta
486411 Canis lupus familiaris
7441 Homo sapiens
407114 Bos taurus
100328957 Oryctolagus cuniculus
303782 Rattus norvegicus
22362 Mus musculus
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