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PBX2 encodes a ubiquitously expressed member of the TALE/PBX homeobox family. Additionally we are shipping PBX2 Proteins (6) and many more products for this protein.
Showing 10 out of 66 products:
Human Polyclonal PBX2 Primary Antibody for EIA, WB - ABIN954018
Qiu, Song, Zhao, Deng, Makino, Tomita, Wang, Luo, Doki, Aozasa, Morii: Expression level of Pre B cell leukemia homeobox 2 correlates with poor prognosis of gastric adenocarcinoma and esophageal squamous cell carcinoma. in International journal of oncology 2010
Show all 3 references for ABIN954018
Human Monoclonal PBX2 Primary Antibody for IHC, WB - ABIN2668699
Stankunas, Shang, Twu, Kao, Jenkins, Copeland, Sanyal, Selleri, Cleary, Chang: Pbx/Meis deficiencies demonstrate multigenetic origins of congenital heart disease. in Circulation research 2008
Human Polyclonal PBX2 Primary Antibody for WB - ABIN2779448
Lehner, Semple, Brown, Counsell, Campbell, Sanderson: Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region. in Genomics 2003
Data have demonstrated the presence of Meis, Pbx, and Prep proteins during early lineage segregation in mammals: Meis1, Meis3, Pbx1, Pbx2, Pbx3, and Prep1 in the mouse.
In compound Pbx1 (show PBX1 Antibodies);Pbx2 and Pbx1 (show PBX1 Antibodies);Emx2 (show EMX2 Antibodies) mutants, pelvic mesenchymal condensation is markedly perturbed, indicative of an upstream control by these homeoproteins.
Despite wide Pbx2 expression, mice homozygous mutant for Pbx2 are born at the expected Mendelian frequencies and exhibit no detectable abnormalities in development and organogenesis or reduction of long-term survival.
Pbx1 (show PBX1 Antibodies)/Pbx2 exert a primary hierarchical function on Hox (show MSH2 Antibodies) genes, rather than behaving merely as Hox (show MSH2 Antibodies) ancillary factors
During pancreatic islet formation, Pax6 (show PAX6 Antibodies) expression becomes dependent upon Pbx1 (show PBX1 Antibodies) and Pbx2 function.
TALE proteins are critical downstream effectors within an essential homeoprotein network that serves a rate-limiting regulatory role in MLL (show MLL Antibodies) leukemogenesis.
Pbx1 (show PBX1 Antibodies)/Pbx2 govern axial skeletal development by controlling Polycomb (show CBX2 Antibodies) and Hox (show MSH2 Antibodies) in mesoderm and Pax1 (show PAX1 Antibodies)/Pax9 (show PAX9 Antibodies) in sclerotome.
Reduction or absence of Pbx2 or Pbx3 leads to Pbx1 (show PBX1 Antibodies) haploinsufficiency and specific malformations that resemble tetralogy of Fallot, overriding aorta with ventricular septal defect, and bicuspid aortic valves.
miR19153p functions as a silencer of apoptosis, which regulates lung cancer apoptosis via targeting DRG2 (show DRG2 Antibodies)/PBX2.
findings suggest the disruption of the HOXB7 (show HOXB7 Antibodies)/PBX2 complexes, miR (show MLXIP Antibodies)-221&222 inhibition or even better their combination, as innovative therapeutic approaches
a high level of PBX2 is a poor prognosticator for disease-free survival and overall survival in gingival squamous cell carcinoma
Pre B cell leukemia homeobox 2 has a role in poor prognosis of gastric adenocarcinoma and esophageal squamous cell carcinoma
a PBX2 Regulatory Element PRE-1048 has been identified which contains a novel DNA-binding sequence and mediates significant activation of the HOX11 (show TLX1 Antibodies) gene in K562 cells.
these studies demonstrate that the homeodomain proteins, MEIS1 (show MEIS1 Antibodies), PBX1B (show PBX1 Antibodies), and PBX2, play an important role in megakaryocytic gene expression.
PBX2 increases in F9 teratocarcinoma cells because PREP-1 prevents its degradation
PBX2 expression pattern is similar to HOXA7 (show HOXA7 Antibodies) expression in ovarian follicular development
Expression levels of PBX2 and VCP were immunohistochemically examined and compared with each other in 206 non-small cell lung cancer cases
A loss of Pbx2 and Pbx4 (show PBX4 Antibodies) causes a significant reduction of hindbrain and spinal cord expression of lbx1 (show Lbx1 Antibodies) genes.
eliminating zebrafish Lzr/Pbx4 (show PBX4 Antibodies) and Pbx2 function prevents hindbrain segmentation and causes a wholesale anterior homeotic transformation of r2-r6, to r1 identity
These data define a novel role for Pbx2 in patterning the vertebrate retina and tectum in a manner required for proper retinal ganglion cell axon outgrowth
This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1\;19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6.
homeobox protein PBX2
, pre B-cell leukemia transcription factor 2
, pre-B-cell leukemia transcription factor 2
, homeobox 12
, pre-B-cell leukemia homeobox 2 pseudogene 1
, pre-B-cell leukemia transcription factor y