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Prickle Homolog 1 (Drosophila) (PRICKLE1) ELISA Kits

PRICKLE1 encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway. Additionally we are shipping PRICKLE1 Antibodies (40) and PRICKLE1 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human PRICKLE1 PRICKLE1 144165 Q96MT3
Anti-Mouse PRICKLE1 PRICKLE1 106042 Q3U5C7
Anti-Rat PRICKLE1 PRICKLE1 315259  
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More ELISA Kits for PRICKLE1 Interaction Partners

Human Prickle Homolog 1 (Drosophila) (PRICKLE1) interaction partners

  1. these findings suggest PRICKLE1 mutations contribute to ASD (show ARSD ELISA Kits) by disrupting the interaction with SYN1 (show SYN1 ELISA Kits) and regulation of synaptic vesicles.

  2. study demonstrates that PRICKLE1 could act as a predisposing factor to human neural tube defects

  3. MINK1 (show MINK1 ELISA Kits) interacts with and phosphorylates PRICKLE1 and PRICKLE2 (show PRICKLE2 ELISA Kits).

  4. Mutations in prickle1 causes seizures.

  5. PRICKLE1 mutations are not a frequent cause of progressive myoclous epilepsies in Southern Italy.

  6. PRICKLE1 and PRICKLE2 (show PRICKLE2 ELISA Kits) mRNAs were expressed together in brain, eye and testis.

  7. appears to serve as a nuclear receptor for REST/NRSF (show REST ELISA Kits), REST4, and possibly other transcription factors

  8. NRSF (show REST ELISA Kits)/REST functions as a repressor of TH transcription in NSCs via a mechanism dependent on the TH NRSE/RE1 (show NPC2 ELISA Kits) sites.

  9. Prickle-1 is a negative regulator of the Wnt/beta-catenin signaling pathway and is a putative tumor suppressor in human hepatocellular carcinoma

  10. there is synergism between REST and NFkappaB (show NFKB1 ELISA Kits) in the suppression of TAC1 (show TAC1 ELISA Kits) in non-neuronal cells

Mouse (Murine) Prickle Homolog 1 (Drosophila) (PRICKLE1) interaction partners

  1. Prickle1 is part of a molecular mechanism that regulates facial branchiomotor neurons caudal (show CAD ELISA Kits) migration.

  2. these findings suggest PRICKLE1 mutations contribute to ASD (show GUSB ELISA Kits) by disrupting the interaction with SYN1 (show SYN1 ELISA Kits) and regulation of synaptic vesicles.

  3. Data suggest Prickle1 is part of the Wnt5a (show WNT5A ELISA Kits)/PCP (show BMP1 ELISA Kits) signaling, regulating cell polarity and affecting expression of multiple factors to stunt limb growth through altered patterns of gene expression, including the PCP (show BMP1 ELISA Kits) genes Wnt5a (show WNT5A ELISA Kits) and Vangl2 (show VANGL2 ELISA Kits).

  4. Pk1 function in axonal-dendritic development associated with the maturation of CNS neurons.

  5. Prickle1 and Prickle2 (show PRICKLE2 ELISA Kits) promote neurite-like process formation of C1300 cells via the Dvl1 (show DVL1 ELISA Kits)-dependent mechanism

  6. These results suggest that RILP(also known as Prickle) expression and function control REST action more so than does REST expression and is an important regulatory role in cardiomyocyte differentiation.

  7. Mutations in prickle1 causes seizures.

  8. both Prickle1 and Prickle2 (show PRICKLE2 ELISA Kits) promote neurite-like process formation of C1300 neuroblastoma (show ARHGEF16 ELISA Kits) cells via the Dishevelled (show DVL2 ELISA Kits) dependent pathway

  9. mouse Prickle1 and Prickle2 (show PRICKLE2 ELISA Kits) possibly regulate positive neurite formation during brain development

  10. Results demonstrate a role for prickle1 in AB polarity formation rather than expected role as a PCP (show BMP1 ELISA Kits) gene.

PRICKLE1 Antigen Profile

Antigen Summary

This gene encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway. The encoded protein localizes to the nuclear membrane and has been implicated in the nuclear trafficking of the transcription repressors REST/NRSF and REST4. Mutations in this gene have been linked to progressive myoclonus epilepsy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3.

Gene names and symbols associated with PRICKLE1

  • prickle homolog 1 (Drosophila) (PRICKLE1) antibody
  • prickle homolog 1 (Drosophila) (Prickle1) antibody
  • 1110058P22Rik antibody
  • AW215793 antibody
  • EPM1B antibody
  • mpk1 antibody
  • Prickle antibody
  • Rilp antibody

Protein level used designations for PRICKLE1

prickle-like 1 , prickle-like protein 1 , REST/NRSF-interacting LIM domain protein 1 , REST (RE-1 silencing transcription factor)/NRSF (neuron-restrictive silencer factor)-interacting LIM domain protein , prickle like 1

GENE ID SPECIES
451838 Pan troglodytes
701864 Macaca mulatta
144165 Homo sapiens
106042 Mus musculus
315259 Rattus norvegicus
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