Pro-Platelet Basic Protein (PPBP) ELISA Kits

The protein encoded by PPBP is a platelet-derived growth factor that belongs to the CXC chemokine family.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human PPBP PPBP 5473 P02775
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More ELISA Kits for Pro-Platelet Basic Protein Interaction Partners

Human Pro-Platelet Basic Protein (PPBP) interaction partners

  1. Two haplotype blocks, one upstream to the coding region of UGT2A1 (show UGT2A1 ELISA Kits) (rs146712414, P = 9.1 x 10(-5); odds ratio [OR], 1.34; 95% confidence interval [CI], 1.16-1.56) and one downstream of the genes PF4 (show PF4 ELISA Kits)/PPBP/CXCL5 (show CXCL5 ELISA Kits) (rs1595009, P = 1.3 x 10(-4); OR, 1.32; 95% CI, 1.15-1.52), were associated with AgP (show USMG5 ELISA Kits).

  2. Cby's C-terminal domain alone binds to TC-1 (show SLC19A2 ELISA Kits) with significantly greater affinity compared to full-length Cby (show CBY1 ELISA Kits), implying that target binding of the coiled-coil domain is affected by the flanking disordered regions.

  3. CXCL7 plays a promoting role in regulating the growth and metastasis of cholangiocarcinoma.

  4. Data suggest that neutrophil-activating peptide 2 (NAP-2) secreted by NK cells can bind to CXC Chemokine Receptor (show CXCR4 ELISA Kits) 2 (CXCR2 (show CXCR2 ELISA Kits)) on mesenchymal stem cells (MSCs) leading to stimulation of its recruitment.

  5. Utilizing mass spectrometry-based proteomics, platelet basic protein has been identified as a candidate serum biomarker for transient ischemic attack

  6. Synovial Cxcl7 mRNA and protein were increased in early rheumatoid arthritis compared to uninflamed controls and resolving arthritis.

  7. Studied and characterized the dynamics and thermodynamic stability of monomer and homodimer structures of CXCL7.

  8. Leptin (show LEP ELISA Kits) and neutrophil-activating peptide act synergistically to promote mesenchymal stem cell senescence through enhancement of the PI3K (show PIK3CA ELISA Kits)/Akt (show AKT1 ELISA Kits) signaling pathway in systemic lupus erythematosus patients.

  9. CXCL7/CXCR2 (show CXCR2 ELISA Kits) signalling pathways are a predictive factor of poor outcome in metastatic colon cancer.

  10. CXCR4 (show CXCR4 ELISA Kits)-CXCL12 (show CXCL12 ELISA Kits)-CXCR7 (show CXCR7 ELISA Kits) regulates mTOR (show FRAP1 ELISA Kits) signaling in renal cancer cells.

Pro-Platelet Basic Protein (PPBP) Antigen Profile

Antigen Summary

The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells.

Gene names and symbols associated with PPBP

  • pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) (PPBP) antibody
  • B-TG1 antibody
  • Beta-TG antibody
  • CTAP-III antibody
  • CTAP3 antibody
  • CTAPIII antibody
  • CXCL7 antibody
  • LA-PF4 antibody
  • LDGF antibody
  • MDGF antibody
  • NAP-2 antibody
  • PBP antibody
  • SCYB7 antibody
  • TC1 antibody
  • TC2 antibody
  • TGB antibody
  • TGB1 antibody
  • THBGB antibody
  • THBGB1 antibody

Protein level used designations for PPBP

C-X-C motif chemokine 7 , CXC chemokine ligand 7 , beta-thromboglobulin , connective tissue-activating peptide III , leukocyte-derived growth factor , low-affinity platelet factor IV , macrophage-derived growth factor , neutrophil-activating peptide 2 , neutrophil-activating peptide-2 , platelet basic protein , small inducible cytokine B7 , small inducible cytokine subfamily B, member 7 , small-inducible cytokine B7 , thrombocidin 1 , thrombocidin 2 , thromboglobulin, beta-1

GENE ID SPECIES
5473 Homo sapiens
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