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POP4 encodes one of the protein subunits of the small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. Additionally we are shipping Processing of Precursor 4, Ribonuclease P/MRP Subunit (S. Cerevisiae) Antibodies (18) and many more products for this protein.
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Human POP4 Protein expressed in Escherichia coli (E. coli) - ABIN1098799
Sharin, Schein, Mann, Ben-Asouli, Jarrous: RNase P: role of distinct protein cofactors in tRNA substrate recognition and RNA-based catalysis. in Nucleic acids research 2005
Show all 2 references for ABIN1098799
Collectively, the present results suggest that PhoRpp21 binds the loop between P11 (show S100A10 Proteins) and P12 (show POLE4 Proteins) helices through overall positively charged clusters on the surface of the complex and serves as a scaffold for PhoRpp29 to optimize structural conformation of its N-terminal helix (alpha2) in PhoRpp21, as well as C-terminal residues in PhoRpp29, for RNase P activity.
Rpp29 represses H3.3 nucleosome deposition, a finding with implications for epigenetic regulation.
This gene encodes one of the protein subunits of the small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. The encoded protein is localized to the nucleus and associates directly with the RNA component of these complexes. This protein is involved in processing of precursor RNAs. Alternative splicing results in multiple transcript variants.
processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)
, ribonuclease P protein subunit p29
, POP4 (processing of precursor , S. cerevisiae) homolog