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anti-Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase 3 (PLOD3) Antibodies

The protein encoded by PLOD3 is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. Additionally we are shipping PLOD3 Kits (4) and PLOD3 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PLOD3 26433 Q9R0E1
PLOD3 288583 Q5U367
PLOD3 8985 O60568
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Top anti-PLOD3 Antibodies at antibodies-online.com

Showing 10 out of 39 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of PLOD3 Antibody (N-term) in MDA-MB435 cell line lysates (35ug/lane). This demonstrates the PLOD3 antibody detected the PLOD3 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB PLOD3 Antibody (N-term) (ABIN656661) western blot analysis in MDA-MB435 cell line lysates (35 µg/lane). This demonstrates the PLOD3 antibody detected the PLOD3 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IF, WB Western Blot analysis of PLOD3 expression in transfected 293T cell line by PLOD3 MaxPab polyclonal antibody.Lane 1: PLOD3 transfected lysate(81.18 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of purified MaxPab antibody to PLOD3 on HeLa cell. [antibody concentration 10 ug/ml] 50 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$527.15
Details
Human Rabbit Biotin ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated WB   50 μL Log in to see 8 to 10 Days
$463.83
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated ELISA, WB   200 μL Log in to see 11 to 16 Days
$532.71
Details
Human Rabbit FITC ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details

PLOD3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)


Rat (Rattus)


Human ,
,

, , , , ,

Top referenced anti-PLOD3 Antibodies

  1. Human Polyclonal PLOD3 Primary Antibody for EIA, WB - ABIN954206 : Wang, Kovanen, Raudasoja, Eskelinen, Pospiech, Myllylä: The glycosyltransferase activities of lysyl hydroxylase 3 (LH3) in the extracellular space are important for cell growth and viability. in Journal of cellular and molecular medicine 2009 (PubMed)
    Show all 5 references for ABIN954206

  2. Human Polyclonal PLOD3 Primary Antibody for IF, WB - ABIN522428 : Amodio, Moltedo, Monteleone, DAmbrosio, Scaloni, Remondelli, Zambrano: Proteomic signatures in thapsigargin-treated hepatoma cells. in Chemical research in toxicology 2011 (PubMed)
    Show all 2 references for ABIN522428

More Antibodies against PLOD3 Interaction Partners

Zebrafish Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase 3 (PLOD3) interaction partners

  1. LH3 directs target-selective motor axon regeneration.

  2. Together these data suggest that Lh3-Collagen18A1 dependent ECM (show MMRN1 Antibodies) modifications regulate the transition of trunk neural crest cells from a non-segmental sheet like migration mode to a segmental stream migration mode

  3. diwanka (lh3) acts through myotomal type XVIII collagen, a ligand for neural-receptor protein tyrosine phosphatases that guide motor axons

Mouse (Murine) Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase 3 (PLOD3) interaction partners

  1. Data indicate that lysyl hydroxylase 3 is essential for the glucosyltion of mannan-binding lectin MBL (show MBL2 Antibodies)-A.

  2. LH3 is an important regulator of adiponectin (show ADIPOQ Antibodies) biosynthesis, secretion and activity.

  3. LH3-mediated glucosylation occurs at the specific molecular loci in the type I collagen molecule and plays critical roles in controlling collagen cross-linking, fibrillogenesis, and mineralization.

  4. the major function of LH3 in osteoblasts is to glucosylate galactosylhydroxylysine residues in type I collagen and that an impairment of this LH3 function significantly affects type I collagen fibrillogenesis.

  5. results demonstrate that LH3 is indispensable for biosynthesis of type IV collagen (show COL4 Antibodies) and for basement membrane stability during early development and that loss of LH3's functions leads to embryonic lethality

  6. LH3 is present and active in the extracellular space

  7. LH3 has lysyl hydroxylase and galactosylhydroxylysyl glucosyltransferase T activities in vivo, and is essential for the formation of the basement membrane

  8. Results report an important role for lysyl hydroxylase 3 in the organization of the extracellular matrix (ECM (show MMRN1 Antibodies)) and cytoskeleton.

Human Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase 3 (PLOD3) interaction partners

  1. The study shows that lysyl hydroxylase 3 localizes to epidermal basement membrane and is reduced in patients with recessive dystrophic epidermolysis bullosa.

  2. MMP-9 (show MMP9 Antibodies) recruitment to the fibroblast cell surface by Lysyl Hydroxylase 3 (LH3) triggers TGF-beta (show TGFB1 Antibodies) activation and fibroblast differentiation

  3. LH3 molecules found in the cell medium are secreted through the Golgi complex, and the secretion is dependent on LH3 glycosyltransferase (show GTDC2 Antibodies) activity; LH3 found on the cell surface bypasses the Golgi complex

  4. Dimerization of human lysyl hydroxylase 3 is mediated by the amino acids 541-547

  5. Characterization of three fragments that constitute the monomers of the human lysyl hydroxylase isoenzymes 1-3. The 30-kDa N-terminal fragment is not required for lysyl hydroxylase activity

  6. Manipulation of the gene for LH3 can be used to selectively alter glycosylation and hydroxylation reactions, and provides new tool to clarify functions of unique hydroxylysine linked carbohydrates in collagens and other proteins.

  7. LH3 is present and active in the extracellular space

  8. The deficiency of LH3 glycosyltransferase (show GTDC2 Antibodies) activities, especially in the extracellular space, causes growth arrest.

  9. mutations of the lysyl hydroxylase 3 gene may cause a connective tissue disorder [case report]

PLOD3 Antigen Profile

Protein Summary

The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity.

Gene names and symbols associated with PLOD3

  • procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 (plod3) antibody
  • procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 (PLOD3) antibody
  • procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 (Plod3) antibody
  • AI414586 antibody
  • cb479 antibody
  • cb816 antibody
  • diwanka antibody
  • DKFZp469I0226 antibody
  • im:6912725 antibody
  • LH3 antibody
  • plod antibody
  • PLOD3 antibody
  • wu:fb72f10 antibody

Protein level used designations for PLOD3

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 , procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 , diw , lh3 , procollagen-lysine,2-oxoglutarate 5-dioxygenase 3-like , lysyl hydroxylase 2 , lysyl hydroxylase 3 , LH3 , bone protein I (BP-I) , lysine hydroxylase 3 , lysyl hydroxlase 3

GENE ID SPECIES
380138 Xenopus laevis
463618 Pan troglodytes
479730 Canis lupus familiaris
514996 Bos taurus
556077 Danio rerio
734090 Xenopus (Silurana) tropicalis
100059479 Equus caballus
100173058 Pongo abelii
100390092 Callithrix jacchus
26433 Mus musculus
288583 Rattus norvegicus
8985 Homo sapiens
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