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Proenkephalin Proteins (PENK)

Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Additionally we are shipping Enkephalin Antibodies (118) and Enkephalin Kits (50) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PENK 71950 Q80Z64
PENK 29237 P04094
PENK 5179 P01210
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Top Enkephalin Proteins at antibodies-online.com

Showing 6 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,082.67
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,091.83
Details
Yeast Guinea Pig His tag   1 mg Log in to see 56 to 66 Days
$2,091.83
Details
HOST_Human Human His tag   10 μg Log in to see 5 Days
$203.50
Details
HOST_Synthetic Human KLH   100 μg Log in to see 11 to 13 Days
$616.00
Details

PENK Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus) ,
,
Human , ,
, ,

More Proteins for Proenkephalin (PENK) Interaction Partners

Zebrafish Proenkephalin (PENK) interaction partners

Mouse (Murine) Proenkephalin (PENK) interaction partners

  1. Nanog is able to transform normal somatic cells into tumor cells.

  2. NANOG represses mitochondrial oxidative phosphorylation genes, as well as reactive oxygen species generation, and activates fatty acid oxidation to support tumor initiating cell self-renewal and drug resistance.

  3. The cellular reprogramming-promoting function of mitoflashes occurs via the upregulation of Nanog expression.

  4. the existence of three stable steady states for Nanog levels, which are the same in all the different conditions of the cell-culture medium.

  5. NANOG (show NANOG Proteins) binds to GLI1 (show GLI1 Proteins) and GLI3 (show GLI3 Proteins) proteins and represses Hedgehog (show SHH Proteins)-mediated transcription.

  6. Tgif1 counterbalances the activity of core pluripotency factors, Oct4, Sox2, and Nanog, in mouse embryonic stem cells.

  7. TLR4 (show TLR4 Proteins) signaling via NANOG (show NANOG Proteins) cooperates with STAT3 (show STAT3 Proteins) to activate Twist1 (show TWIST1 Proteins) and promote formation of tumor-initiating stem-like cells in livers of mice.

  8. Nav1.7 (show SCN9A Proteins) deletion has profound effects on gene expression, leading to an upregulation of enkephalin precursor Penk mRNA and met-enkephalin protein in sensory neurons.

  9. Pluripotency transcription factors Nanog (show NANOG Proteins) and Oct4 (show POU5F1 Proteins) positively modulate Sod2 (show SOD2 Proteins) gene transcription in induced pluripotent stem cells.

  10. NANOG alone induces germ cells in primed epiblast in vitro by activation of enhancers

Pig (Porcine) Proenkephalin (PENK) interaction partners

  1. The expression of the genes coding for proopiomelanocortin (POMC (show POMC Proteins)), proenkephalin (PENK) and prodynorphin (PDYN (show PDYN Proteins)) in porcine luteal cells isolated from corpora lutea (CL) collected on days 3-6, 8-10 and 13-16 of the oestrous cycle is reported.

Human Proenkephalin (PENK) interaction partners

  1. Nav1.7 (show SCN9A Proteins) deletion has profound effects on gene expression, leading to an upregulation of enkephalin precursor Penk mRNA and met-enkephalin protein in sensory neurons.

  2. The PENK polymorphism-and potentially opioid neurotransmission more generally-modulates functioning and structural integrity of brain regions.

  3. Serum PENK-A levels were not associated with all-cause mortality in patients with type 2 diabetes mellitus, and its association with cardiovascular mortality was strongly attenuated after accounting for all traditional risk factors.

  4. BSP (show KLK6 Proteins) demonstrated that emodin, to a certain degree, affected the demethylation of tumor-suppressor genes P16, RASSF1A (show RASSF1 Proteins), and ppENK in the pancreatic cancer cell line PANC-1.

  5. increased plasma PENK-A levels are associated with disease severity and in-hospital mortality after acute intracerebral hemorrhage.

  6. enhanced plasma proenkephalin A could be a useful, complementary tool to predict short- or long-term clinical outcome after severe traumatic brain injury.

  7. EPS led to the discovery of two novel immunomodulatory proteins, MFAP5 (show MFAP5 Proteins) and PENK that when administered to mice subjected to endotoxemic shock, reversed the cytokine storm and provided a significant survival benefit

  8. Data from women undergoing hysterectomy for uterine fibroids suggest that uterine isthmian-cervical region exhibits nerve fibers expressing enkephalin (ENK); uterine fundus/corpus myoma pseudocapsules do not exhibit nerve fibers expressing ENK.

  9. Promoter methylation of WIF1 (show WIF1 Proteins), PENK and NPY (show NPY Proteins) is associated with colorectal adenocarcinoma (CRC (show CALR Proteins)) diagnosis and can be used to CRC (show CALR Proteins) from other cancers.

  10. Expression of preproenkephalin is significantly decreased in brain from HIV-1 infected patients compared to HIV-1 negative subjects.

Enkephalin (PENK) Protein Profile

Protein Summary

Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT-3'. When overexpressed, promotes cells to enter into S phase and proliferation (By similarity).

Gene names and symbols associated with Proenkephalin Proteins (PENK)

  • proenkephalin (PENK)
  • Proenkephalin A (penk)
  • proenkephalin b (penkb)
  • proenkephalin (penk)
  • proenkephalin a (penka)
  • Nanog homeobox (Nanog)
  • preproenkephalin (Penk)
  • preproenkephalin, related sequence (Penk-rs)
  • proenkephalin (Penk)
  • 2410002E02Rik protein
  • AI326464 protein
  • ecat4 protein
  • Enk protein
  • Penk protein
  • Penk-rs protein
  • Penk1 protein
  • Penk2 protein
  • penkl protein
  • PPA protein
  • zgc:73353 protein

Protein level used designations for Proenkephalin Proteins (PENK)

proenkephalin , Proenkephalin A , PENKa , PENKb , proenkephalin-A , enkephalin a , ES cell-associated protein 4 , early embryo specific expression NK family , early embryo specific expression NK-type homeobox protein , homeobox protein NANOG , homeobox transcription factor Nanog , preproenkephalin 1 , spermatogenic-specific proenkephalin , enkephalin , preproenkephalin 2 , proenkephalin 1 , proenkephalin 2 , proenkephalin related sequence , enkephalin A , preproenkephalin

GENE ID SPECIES
421131 Gallus gallus
477889 Canis lupus familiaris
100196814 Salmo salar
100294557 Ovis aries
464186 Pan troglodytes
360136 Danio rerio
495184 Xenopus laevis
368228 Danio rerio
548461 Xenopus (Silurana) tropicalis
71950 Mus musculus
18619 Mus musculus
100379621 Cavia porcellus
101098113 Felis catus
100152093 Sus scrofa
29237 Rattus norvegicus
768277 Felis catus
5179 Homo sapiens
281387 Bos taurus
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