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Profilin 1 (PFN1) ELISA Kits

The protein encoded by PFN1 is a ubiquitous actin monomer-binding protein belonging to the profilin family. Additionally we are shipping Profilin 1 Antibodies (74) and Profilin 1 Proteins (30) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
PFN1 5216 P07737
PFN1 18643 P62962
PFN1 64303 P62963
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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 27 pg/mL 78.13-5000 pg/mL 96 Tests Log in to see 9 to 11 Days
  96 Tests Log in to see 11 to 13 Days
  96 Tests Log in to see 11 to 13 Days
  96 Tests Log in to see 11 to 13 Days

More ELISA Kits for Profilin 1 Interaction Partners

Human Profilin 1 (PFN1) interaction partners

  1. evidence, which suggests that Profilin increases tumour suppressor activity by regulating NF-kappaB (show NFKB1 ELISA Kits).

  2. Profilin-1 folding process occurs in the absence of thermodynamically stable partially folded states.

  3. Actin independent mechanisms contribute to the pathogenicity of PFN1 T109M and possibly other PFN1 mutations.

  4. expression of the ALS (show IGFALS ELISA Kits)-associated actin-binding deficient mutant of PFN1 (PFN1(C71G)) results in increased dendritic arborisation and spine formation, and cytoplasmic inclusions in cultured mouse hippocampal neurons

  5. PFN1 is a rare cause of ALS.

  6. findings suggest that a destabilized form of PFN1 underlies PFN1-mediated ALS pathogenesis

  7. Suggest that PFN1 plays a critical role in gastric carcinoma progression, and these effects are likely mediated through the integrin beta1/FAK (show PTK2 ELISA Kits) pathway.

  8. Data indicated that No PFN1 mutations were identified in the Catalan population with amyotrophic lateral sclerosis.

  9. Profilin-1 overexpression in MDA-MB-231 breast cancer cells is associated with alterations in proteomics biomarkers of cell proliferation, survival, and motility as revealed by global proteomics analyses

  10. Profilin1 acts as a molecular regulator of the levels of PI(3,4)P2 and Tks5 recruitment in invadopodia to control the invasion efficiency of invadopodia.

Mouse (Murine) Profilin 1 (PFN1) interaction partners

  1. knockdown of either profilin 1 or profilin 2a led to a significant decrease in cell spreading of astrocytes. Moreover, both isoforms proved to be crucial for forskolin-induced astrocytic stellation.

  2. Inactivation of profilin 1 impaired the radial migration of cerebellar granule neurons

  3. Megakaryocyte-specific Profilin1-deficiency alters microtubule stability and causes a Wiskott-Aldrich syndrome-like (show WASL ELISA Kits) platelet defect.

  4. Depleting FMNL1 (show FMNL1 ELISA Kits), another Formin (show FMN1 ELISA Kits) family member, resulted in reduced mDia1 expression, while RhoA (show RHOA ELISA Kits) inhibition did not alter mDia1 expression, which indicated that there was a FMNL1 (show FMNL1 ELISA Kits)-mDia1-Profilin1 signaling pathway in mouse oocytes.

  5. association of cortactin (show CTTN ELISA Kits) with Pfn-1 is regulated by c-Abl (show ABL1 ELISA Kits)-mediated cortactin (show CTTN ELISA Kits) phosphorylation

  6. In glioblastomas endothelial cell-specific Pfn-1 phosphorylation elevates HIF-1alpha (show HIF1A ELISA Kits) expression leading to vascular abnormalities and tumor progression.

  7. Pfn1 as a key effector of the integrin linked kinase/Rho/ROCK pathway which acts in parallel with integrin beta1/LCK/Rac1 and regulates Schwann cells lamellipodia formation, radial sorting and myelination during peripheral nervous system maturation.

  8. pfn1 at least partially acts through the axis of pfn1/Galpha13/EGR1 (show EGR1 ELISA Kits) to regulate stem cell retention and metabolism in the bone marrow.

  9. findings indicate that pfn haploinsufficiency protects against diet-induced insulin (show INS ELISA Kits) resistance and inflammation by modulating white adipose tissue immune homeostasis.

  10. The results of this study found that the profilin1 is crucially important for brain development, but dispensable for the physiology of excitatory synapses.

Cow (Bovine) Profilin 1 (PFN1) interaction partners

  1. biophysical analysis reveals that the open nucleotide pocket of the profilin/actin x-ray structure is unstable and closes in the absence of profilin

  2. nitric oxide and free radicals produced under different conditions could alter the functions of profilin through nitration, such as its interaction with actin and poly (l-proline).

  3. Profilin regulates actin dynamics both within the cytoplasm and inside the nuclei of developing mammalian embryos.

  4. Phosphorylation studies indicate that profilin dimers are not phosphorylated while teramers are preferentially phosphorylated over monomers.

Arabidopsis thaliana Profilin 1 (PFN1) interaction partners

  1. PRF1 coordinates the stochastic dynamic properties of actin filaments by modulating formin-mediated actin nucleation and assembly during plant cell expansion.

  2. formed a filamentous network likely associated with actin filaments

Caenorhabditis elegans (C. elegans) Profilin 1 (PFN1) interaction partners

  1. protein CYK-1 and the profilin PFN-1 mediate the Arp2/3-independent assembly of cortical microfilaments and are required for cytokinesis in the early embryo

  2. Thus the model organism Caenorhabditis elegans expresses three profilin isoforms and is the first invertebrate animal with tissue-specific profilin expression.

  3. profilin promotes actin organisation

Profilin 1 (PFN1) Antigen Profile

Antigen Summary

This gene encodes a member of the profilin family of small actin-binding proteins. The encoded protein plays an important role in actin dynamics by regulating actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome, and the encoded protein may also play a role in Huntington disease. Multiple pseudogenes of this gene are located on chromosome 1.

Gene names and symbols associated with Profilin 1 (PFN1) ELISA Kits

  • profilin (PRO2) antibody
  • profilin 1 (PFN1) antibody
  • profilin 1 (pfn1) antibody
  • profilin 1 (Pfn1) antibody
  • profilin 1 (PRF1) antibody
  • profilin 1-like (LOC100350198) antibody
  • profilin homolog1 (prf1) antibody
  • profilin-1-like (LOC607397) antibody
  • Protein PFN-1 (pfn-1) antibody
  • ALS18 antibody
  • F6F22.21 antibody
  • F6F22_21 antibody
  • GmPRO1 antibody
  • GmPRO2 antibody
  • MGC130883 antibody
  • Pfn antibody
  • PFN1 antibody
  • PRO1 antibody
  • profilin antibody
  • profilin-1 antibody
  • profilin 1 antibody
  • Profilin1 antibody
  • sb:cb813 antibody
  • wu:fa91a03 antibody
  • XProfilin1 antibody

Protein level used designations for Profilin 1 (PFN1) ELISA Kits

profilin-2 , profilin 1 , fa91a03 , epididymis tissue protein Li 184a , profilin I , profilin-1 , actin binding protein , CL2097_1 , CL2097_1(520) , CL2097_1_ov , ZmPRO1

547670 Glycine max
710753 Macaca mulatta
735169 Xenopus laevis
799355 Danio rerio
100170559 Xenopus (Silurana) tropicalis
5216 Homo sapiens
100512494 Sus scrofa
18643 Mus musculus
64303 Rattus norvegicus
513895 Bos taurus
100723625 Cavia porcellus
816495 Arabidopsis thaliana
100350198 Oryctolagus cuniculus
542409 Zea mays
607397 Canis lupus familiaris
173161 Caenorhabditis elegans
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