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Binds to actin and affects the structure of the cytoskeleton. Additionally we are shipping Profilin 4 Antibodies (9) and Profilin 4 Kits (3) and many more products for this protein.
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Human PFN4 Protein expressed in Escherichia coli (E. coli) - ABIN666964
Behnen, Murk, Kursula, Cappallo-Obermann, Rothkegel, Kierszenbaum, Kirchhoff: Testis-expressed profilins 3 and 4 show distinct functional characteristics and localize in the acroplaxome-manchette complex in spermatids. in BMC cell biology 2009
Show all 2 references for ABIN666964
Human PFN4 Protein expressed in Escherichia coli (E. coli) - ABIN2006402
Carlsson, Nyström, Sundkvist, Markey, Lindberg: Actin polymerizability is influenced by profilin, a low molecular weight protein in non-muscle cells. in Journal of molecular biology 1978
PRF4 and PRF5 regulate actin polymerization in pollen grains and tubes.
Porfilin 4 bound to selected phosphoinositides but not to poly-L-proline, proline-rich proteins, or actin.
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Has a high affinity for poly-proline.
, profilin IV
, profilin 4