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PGRMC1 encodes a putative membrane-associated progesterone steroid receptor. Additionally we are shipping PGRMC1 Antibodies (38) and PGRMC1 Proteins (11) and many more products for this protein.
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These results indicate that maintenance of Pgrmc1 signaling is required for Egfr (show EGFR ELISA Kits) expression on zebrafish oocyte cell membranes and for conserving the functions of Egfr (show EGFR ELISA Kits) in maintaining meiotic arrest through estrogen activation of Gper (show GPER ELISA Kits).
It can be suggested that women with breast epithelium highly expressing PGRMC1 and in interaction with ERalpha (show ESR1 ELISA Kits) may have an increased risk to develop breast cancer.
These results clarify that PGRMC1 and the S2R are distinct binding sites expressed by different genes.
Haem-mediated PGRMC1 dimerization is required for interactions with EGFR (show EGFR ELISA Kits) and cytochromes P450 (show CYP2B6 ELISA Kits), cancer proliferation and chemoresistance against anti-cancer drugs.
indicate that PGRMC1 regulates hepcidin (show HAMP ELISA Kits) gene expression through an evolutionarily conserved mechanism
results suggested that PGRMC1 and sigma2 receptors are two different molecular entities.
PGRMC1 is the major progesterone receptor (show PGR ELISA Kits) eliciting the protective effects of Norgestrel, a synthetic female progesterone hormone.
coding mutations of PGRMC1 do not seem to be a common cause of the disease in Han Chinese
PGRMC1 overexpression led to the epithelial-mesenchymal transition and chemoresistance in uterine sarcoma.
Loss of PGRMC1 expression is associated with endometrial tumor cell viability during chemotherapeutic stress.
PGRMC1 binds to key components of the autophagy machinery and is required for the degradative activity of autophagy
PGRMC1 protein expression and cellular distribution in cumulus cells
data indicate variable expression of progesterone receptor membrane component 1 and 2 and serpine mRNA binding protein 1 mRNA and protein in bovine corpus luteum and suggest that progesterone may regulate corpus luteum function via its membrane receptors
Alterations in PGRMC1 and/or AURKB (show AURKB ELISA Kits) localization account in part for the increased aneuploidy and low development competence of oocytes from ovaries with reduced antral follicle counts.
Data suggest that expression of PGRMC1 in bovine oviduct is primarily in luminal epithelium and is primarily cytoplasmic. Expression of PR (progesterone receptor (show PGR ELISA Kits)), PGRMC1, and PGRMC2 (show PGRMC2 ELISA Kits) are not affected by pregnancy or presence of corpus luteum.
analysis of expression of progesterone receptor membrane component 1, serpine mRNA binding protein 1 and nuclear progesterone receptor (show PGR ELISA Kits) isoforms A and B in the bovine myometrium during the estrous cycle and early pregnancy
With the exception of the corpora lutea, PGRMC1 localization showed similar pattern during different stages of the estrous cycle.
PGRMC1 is expressed in bovine oocytes and its localization changes at specific stages of oocyte maturation, which may be specifically related to the mechanism by which chromosomes segregate.
PGRMC1 mRNA is expressed in bovine CL and this expression varies throughout the luteal phase. It is assumed that PGRMC1 may be involved in a non-genomic effect of P(4) on luteal cells.
PGRMC1 expressed on the cell surface of beta cells was shown to interact with the activated GLP-1R (show GLP1R ELISA Kits) to enhance the insulinotropic actions of GLP-1 (show GCG ELISA Kits).
The aim of this study was to assess the expression, localization and hormonal regulation of two novel P(4) receptor candidates, P(4) receptor membrane component (PGRMC) 1 and PGRMC2 (show PGRMC2 ELISA Kits), as well as the PGRMC1 partner Serpine 1 (show SERPINE1 ELISA Kits) mRNA binding protein (SERBP1 (show SERBP1 ELISA Kits)).
This gene encodes a putative membrane-associated progesterone steroid receptor. The protein is expressed predominantly in the liver and kidney.
progesterone receptor membrane component 1
, membrane-associated progesterone receptor component 1
, progesterone binding protein
, steroid membrane binding protein
, acidic 25 kDa protein
, membrane-bound progesterone receptor
, ventral midline antigen