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May have a role in the regulation of spermatogenesis.. Additionally we are shipping PD-1 Proteins (75) and PD-1 Kits (13) and many more products for this protein.
Showing 10 out of 608 products:
Human Polyclonal PD-1 Primary Antibody for EIA, WB - ABIN401428
Zhong, Bai, Gao, Strom, Rothstein: Suppression of expression and function of negative immune regulator PD-1 by certain pattern recognition and cytokine receptor signals associated with immune system danger. in International immunology 2004
Show all 4 references for ABIN401428
Human Polyclonal PD-1 Primary Antibody for EIA, IHC (p) - ABIN500457
Holling, Schooten, van Den Elsen: Function and regulation of MHC class II molecules in T-lymphocytes: of mice and men. in Human immunology 2004
Show all 4 references for ABIN500457
Human Monoclonal PD-1 Primary Antibody for EIA, WB - ABIN263912
Freeman, Long, Iwai, Bourque, Chernova, Nishimura, Fitz, Malenkovich, Okazaki, Byrne, Horton, Fouser, Carter, Ling, Bowman, Carreno, Collins, Wood, Honjo: Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. in The Journal of experimental medicine 2000
Show all 4 references for ABIN263912
Human Polyclonal PD-1 Primary Antibody for ELISA, WB - ABIN185400
Nielsen, Laustrup, Voss, Junker, Husby, Lillevang: A putative regulatory polymorphism in PD-1 is associated with nephropathy in a population-based cohort of systemic lupus erythematosus patients. in Lupus 2004
Show all 4 references for ABIN185400
Mouse (Murine) Monoclonal PD-1 Primary Antibody for FACS - ABIN951271
Agata, Kawasaki, Nishimura, Ishida, Tsubata, Yagita, Honjo: Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes. in International immunology 1997
Show all 2 references for ABIN951271
Mouse (Murine) Monoclonal PD-1 Primary Antibody for FACS - ABIN951269
Ansari, Salama, Chitnis, Smith, Yagita, Akiba, Yamazaki, Azuma, Iwai, Khoury, Auchincloss, Sayegh: The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice. in The Journal of experimental medicine 2003
Show all 2 references for ABIN951269
Mouse (Murine) Polyclonal PD-1 Primary Antibody for FACS - ABIN4896838
Lee, Rigby, Zotos, Tsai, Kawamoto, Marshall, Ramiscal, Chan, Gatto, Brink, Yu, Fagarasan, Tarlinton, Cunningham, Vinuesa: B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells. in The Journal of experimental medicine 2011
Based on the PD-L1 (show CD274 Antibodies) receptor PD-1 expression on tumor-infiltrating cytotoxic cells, our data supported that expression of PD-L1 (show CD274 Antibodies) on TAM (show CCNA1 Antibodies) promoted apoptosis of T cells via interaction with PD-1 on CD8 (show CD8A Antibodies)(+)T cells.
The incidence of PD-1 inhibitor-related pneumonitis was higher in non-small cell lung cancer and renal cell carcinoma (show MOK Antibodies) during combination therapy. These findings contribute to enhance awareness among clinicians and support further investigations to meet the clinical needs
Our findings support an association between the PD-1 rs2227982 polymorphism and decreased breast cancer risk, especially in Her-2 (show ERBB2 Antibodies) positive breast cancer patients in the Chinese population.
High PD-1 expression is associated with Hodgkin's lymphoma.
Our study revealed that RANK-L is a promising marker to forecast pts (show PTS Antibodies)' prognosis in AML (show RUNX1 Antibodies). Immune checkpoint receptor PD-1/L as well as RANK and HLA-ABC (show ABCB6 Antibodies) did not show an impact on pts (show PTS Antibodies)' survival.
The PD-1/PD-L1 (show CD274 Antibodies) checkpoint blockade, which targets regulatory pathways in T cells to overcome immune resistance, is correlated to PD-L1 (show CD274 Antibodies) expression pattern and the presence of tumor-infiltrating lymphocytes (TILs). Meanwhile, immunogenic mutation loads show significant response to checkpoint blockade, which is probably due to PD-1/L1 status and TIL (show TLR1 Antibodies) content
The expression rate of PDCD1 in extranodal NK/T-cell lymphoma patients was very low.
Study demonstrates that PD-1(+) TIMC and intratumoral PD-L1 (show CD274 Antibodies)(+) expression did not significantly impact tumor aggressiveness or clinical outcome in non-ccRCC specimens.
Immune surveillance is an important mechanism in prevention of cancer development and inhibition of growth of tumors and metastasis. Checkpoint pathways prevent immune response through multiple methods including CTLA-4 (show CTLA4 Antibodies) and PD-1/PD-L1 (show CD274 Antibodies) pathways.A variety of immune checkpoint inhibitors (PD-1/PD-L1 (show CD274 Antibodies) and CTLA-4 (show CTLA4 Antibodies) inhibitors) have been studied in recurrent and metastatic head and neck cancers with encouraging efficacy
n combination with anti-PD-1/PD-L1 (show CD274 Antibodies), the CTLA-4 (show CTLA4 Antibodies)-expanded T cells are prevented from being functionally inhibited when they enter into the tumor microenvironment.
Tim-3 (show HAVCR2 Antibodies)(+) PD-1(+) CD8 (show CD8A Antibodies)(+) T cells showed more evident properties associated with exhaustion than Tim-3 (show HAVCR2 Antibodies)(-) PD-1(+) CD8 (show CD8A Antibodies)(+) T cells.
that porcine islet-specific tolerance is dependent on PD-1, which could not be extended to skin grafts
Programmed cell death-1 engagement followed by zymosan stimulation might primarily attenuate the phosphorylation of tyrosine residue in Programmed cell death-1 receptor/ligand.
Study suggests that expression of the inhibitory receptors PD-1 and LAG-3 (show LAG3 Antibodies) on CD4 (show CD4 Antibodies)(+) T cells and their reduced IL-2 (show IL2 Antibodies) production are common characteristic features of Plasmodium infection.
these data suggest a scenario in which microglia are involved in the regulation of experimental autoimmune encephalomyelitis by suppressing Th1 (show HAND1 Antibodies)-cell differentiation via the PD-L1 (show CD274 Antibodies)-nitric oxide pathway.
Blockade of TGFbeta (show TGFB1 Antibodies) downregulated PD-1 and PD-L1 (show CD274 Antibodies) expression and precipitated graft rejection.
PD-1 regulates peripheral T-cell responses in both human and murine rheumatoid arthritis
LAG3 (show LAG3 Antibodies) and PD1 co-inhibitory molecules have roles in collaborating to limit CD8 (show CD8A Antibodies)+ T cell signaling and dampen antitumor immunity in a murine ovarian cancer model
Decidual NK, NKT (show CTSL1 Antibodies) and gamma/delta T cells showed increased PD-1 expression and reduced cytotoxic potential when compared to the periphery.
The endogenous PD-1/PD-L pathway does not limit acute experimental foreign antigen-induced circulating immune complex glomerulonephritis.
May have a role in the regulation of spermatogenesis.
programmed cell death 1
, programmed cell death protein 1
, protein PD-1
, programmed death 1
, spermatogenesis associated PD1
, spermatogenesis-associated protein 2
, spermatogenesis-associated protein PD1