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May have a role in the regulation of spermatogenesis.. Additionally we are shipping PD-1 Proteins (88) and PD-1 Kits (20) and many more products for this protein.
Showing 10 out of 617 products:
Human Polyclonal PD-1 Primary Antibody for ELISA (Detection), FACS - ABIN4899871
Sakthivel, Ramanujam, Wang, Pirskanen, Lefvert: Programmed Death-1: from gene to protein in autoimmune human myasthenia gravis. in Journal of neuroimmunology 2008
Show all 7 references for ABIN4899871
Human Polyclonal PD-1 Primary Antibody for EIA, WB - ABIN401428
Zhong, Bai, Gao, Strom, Rothstein: Suppression of expression and function of negative immune regulator PD-1 by certain pattern recognition and cytokine receptor signals associated with immune system danger. in International immunology 2004
Show all 4 references for ABIN401428
Human Monoclonal PD-1 Primary Antibody for EIA, WB - ABIN263912
Freeman, Long, Iwai, Bourque, Chernova, Nishimura, Fitz, Malenkovich, Okazaki, Byrne, Horton, Fouser, Carter, Ling, Bowman, Carreno, Collins, Wood, Honjo: Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. in The Journal of experimental medicine 2000
Show all 4 references for ABIN263912
Human Polyclonal PD-1 Primary Antibody for ELISA, WB - ABIN185400
Nielsen, Laustrup, Voss, Junker, Husby, Lillevang: A putative regulatory polymorphism in PD-1 is associated with nephropathy in a population-based cohort of systemic lupus erythematosus patients. in Lupus 2004
Show all 4 references for ABIN185400
Human Polyclonal PD-1 Primary Antibody for EIA, IHC (p) - ABIN500457
Holling, Schooten, van Den Elsen: Function and regulation of MHC class II molecules in T-lymphocytes: of mice and men. in Human immunology 2004
Show all 4 references for ABIN500457
Mouse (Murine) Monoclonal PD-1 Primary Antibody for FACS - ABIN951270
Agata, Kawasaki, Nishimura, Ishida, Tsubata, Yagita, Honjo: Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes. in International immunology 1997
Show all 2 references for ABIN951270
Mouse (Murine) Polyclonal PD-1 Primary Antibody for FACS - ABIN4896838
Lee, Rigby, Zotos, Tsai, Kawamoto, Marshall, Ramiscal, Chan, Gatto, Brink, Yu, Fagarasan, Tarlinton, Cunningham, Vinuesa: B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells. in The Journal of experimental medicine 2011
Gastric adenocarcinoma patients present with increased PD-1(+) lymphocytes and CD4 (show CD4 Antibodies)(+)CD25 (show IL2RA Antibodies)(+)FOXP3 (show FOXP3 Antibodies)(+) regulatory T cells in the peripheral blood.
this study shows that that Tim-3 (show HAVCR2 Antibodies) expression defines a subpopulation of PD-1+ exhausted NY-ESO-1 (show CTAG1B Antibodies)-specific CD8 (show CD8A Antibodies)+ T cell and PD-1+Tim-3 (show HAVCR2 Antibodies)+ CD8 (show CD8A Antibodies)+ T cells represented the largest subset of NY-ESO-1 (show CTAG1B Antibodies)-specific CD8 (show CD8A Antibodies)+ T cells in gastric cancer patients
PD-1 up-regulation drives the immunologic deficits associated with sarcoidosis.
The predicted PUB domain in the N-terminus of SPATA2 interacts with the USP domain of CYLD and SPATA2 is required for recruitment of CYLD to the TNF-alpha receptor-associated signaling complexes.
PD-1 expression was positively correlated with CD38 and HLA-DR expressions on CD8 (show CD8A Antibodies)(+)T cells in HIV-1 infected patients.
Increased expression of PD-L1 (show CD274 Antibodies) by immunohistochemistry was observed as the eruption progressed to toxic epidermal necrolysis . Early diagnosis and treatment is necessary in these fatal toxic epidermal necrolysis reactions secondary to the anti-PD-1 antibody therapies.
The expression levels of PD-1, PD-L1 (show CD274 Antibodies) and PD-L2 (show PDCD1LG2 Antibodies) in CD3 (show CD3 Antibodies)(+) T cells and CD19 (show CD19 Antibodies)(+) B cells and serum IFN-gamma (show IFNG Antibodies) level in progressive hepatocellular carcinoma patients were significantly higher than controls.
PD-1 is overexpressed in IL-17A (show IL17A Antibodies)-producing T cells in both imiquimod-treated mice and patients with psoriasis. Moreover, recombinant PD-L1 (show CD274 Antibodies)-Fc alleviates psoriatic inflammation in imiquimod-treated mice.
PD-1 receptor has a role in interacting with programmed cell death ligands and B7-1 (show CD80 Antibodies)
Downregulation of the immunosuppressive molecules, PD-1 and PD-L1 (show CD274 Antibodies), may imply that over-activation of immune cells in multiple sclerosis occurs through signaling dysfunction of these molecules and PD-L2 (show PDCD1LG2 Antibodies) plays no important role in this context
we provide evidence that indicates that the PD-1(+) fraction of DN T cells represents self-reactive cells.
PD-1 is upregulated in CD4 (show CD4 Antibodies)+ T cells in Schistosoma japonicum (S. japonicum)-infected mice.
Findings indicated that METH (show MTRR Antibodies) induced the upregulation of PD-1 expression which altered the cytokine production as well as cytotoxic functions in mouse model of lymphocytic choriomeningitis virus infection.
Taken together, our data demonstrate the importance of CD40 (show CD40 Antibodies) signaling in the conversion of CTL exhaustion and its ability to enhance PD-1 antagonist action in rescuing exhausted CTLs in chronic infection.
Our proteogenomic analysis demonstrates a role of Smad4 (show SMAD4 Antibodies) loss in the PD-L1 (show CD274 Antibodies) immune evasion, as well as Il1rl1 (show IL1RL1 Antibodies)'s role in CSC-like properties of NCC (show SLC12A3 Antibodies)-S1M.
Combination with anti-programmed cell death protein-1 (PD-1) antibodies promoted complete tumor rejection, indicating the relevance of CD25 antigen (show IL2RA Antibodies) as a therapeutic target and promising substrate for future combination approaches in immune-oncology.
These studies indicate that PD-1 is a critical homeostatic regulator for Tregs by modulating proliferation and apoptosis during IL-2 (show IL2 Antibodies) therapy.
data defined PD-1(hi)IL-25R(hi) as an early checkpoint in Innate lymphoid cell development; results provide a perspective for exploring PD-1 and its ligand (PD-L1 (show CD274 Antibodies)) in immunotherapy, and allow effective manipulation of the immune system for disease prevention and therapy
May have a role in the regulation of spermatogenesis.
programmed cell death 1
, programmed cell death protein 1
, protein PD-1
, programmed death 1
, spermatogenesis associated PD1
, spermatogenesis-associated protein 2
, spermatogenesis-associated protein PD1