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May have a role in the regulation of spermatogenesis.. Additionally we are shipping PD-1 Proteins (96) and PD-1 Kits (22) and many more products for this protein.
Showing 10 out of 642 products:
Human Polyclonal PD-1 Primary Antibody for ELISA (Detection), FACS - ABIN4899871
Sakthivel, Ramanujam, Wang, Pirskanen, Lefvert: Programmed Death-1: from gene to protein in autoimmune human myasthenia gravis. in Journal of neuroimmunology 2008
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Human Polyclonal PD-1 Primary Antibody for EIA, WB - ABIN401428
Zhong, Bai, Gao, Strom, Rothstein: Suppression of expression and function of negative immune regulator PD-1 by certain pattern recognition and cytokine receptor signals associated with immune system danger. in International immunology 2004
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Human Monoclonal PD-1 Primary Antibody for EIA, WB - ABIN263912
Freeman, Long, Iwai, Bourque, Chernova, Nishimura, Fitz, Malenkovich, Okazaki, Byrne, Horton, Fouser, Carter, Ling, Bowman, Carreno, Collins, Wood, Honjo: Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. in The Journal of experimental medicine 2000
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Human Polyclonal PD-1 Primary Antibody for ELISA, WB - ABIN185400
Nielsen, Laustrup, Voss, Junker, Husby, Lillevang: A putative regulatory polymorphism in PD-1 is associated with nephropathy in a population-based cohort of systemic lupus erythematosus patients. in Lupus 2004
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Mouse (Murine) Polyclonal PD-1 Primary Antibody for FACS, IHC - ABIN4899873
Kasagi, Kawano, Okazaki, Honjo, Morinobu, Hatachi, Shimatani, Tanaka, Minato, Kumagai: Anti-programmed cell death 1 antibody reduces CD4+PD-1+ T cells and relieves the lupus-like nephritis of NZB/W F1 mice. in Journal of immunology (Baltimore, Md. : 1950) 2010
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Mouse (Murine) Monoclonal PD-1 Primary Antibody for FACS - ABIN951271
Agata, Kawasaki, Nishimura, Ishida, Tsubata, Yagita, Honjo: Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes. in International immunology 1997
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Mouse (Murine) Monoclonal PD-1 Primary Antibody for FACS - ABIN951270
Ansari, Salama, Chitnis, Smith, Yagita, Akiba, Yamazaki, Azuma, Iwai, Khoury, Auchincloss, Sayegh: The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice. in The Journal of experimental medicine 2003
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Mouse (Murine) Polyclonal PD-1 Primary Antibody for FACS - ABIN4896838
Lee, Rigby, Zotos, Tsai, Kawamoto, Marshall, Ramiscal, Chan, Gatto, Brink, Yu, Fagarasan, Tarlinton, Cunningham, Vinuesa: B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells. in The Journal of experimental medicine 2011
Together, our results suggest an important role of PD-1 in glioma-induced immune escape, and provide translational evidence for the use of PD-1 blocking antibodies in human malignant gliomas.
High PD1 expression is associated with head and neck cancer.
Decreased expression of PD1 mRNA led to Left ventricular dysfunction and functional dysregulation of cellular immunity that may work in the etiopathogenesis of Peripartum Cardiomyopathy.
High PD-1 expression is associated with Non-Small-Cell Lung Cancer.
PD-1 checkpoint blockade has a role in resisting tumor-mediated inhibition
PD1 underexpression is associated with Non-Small-Cell Lung Cancer.
PD-1 is required for maintaining the number, and hence function, of KLRG1 (show KLRG1 Antibodies)(+) Group 2 innate lymphoid cells.
In cutaneous diffuse large b-cell lymphoma, a considerable proportion of CD33 (show CD33 Antibodies)(+) myeloid-derived suppressor cells (MDSCs) with PD-L1 (show CD274 Antibodies) coexpression was admixed. Tumor cells expressed CD33 (show CD33 Antibodies) to variable degrees (2% to 60%). We propose that PD-L1 (show CD274 Antibodies)(+) tumor cells and PD-L1 (show CD274 Antibodies)(+) MDSCs shield the tumor against PD-1(+) tumor-infiltrating lymphocytes, consequently leading to inhibition and diminution of tumor-infiltrating lymphocytes.
Autoimmune hepatitis (AIH) AIH patients with active disease and incomplete response to standard treatment have similarly increased sPD (show HOXD13 Antibodies)-1 levels. AIH patients have increased ability to up-regulate PD-1 following in vitro activation.
All anaplastic thyroid cancer samples demonstrated PD-1 expression in inflammatory cells whereas tumor cells were primarily negative.
study found that Bcl6 positively regulates PD-1 expression by inhibiting the ability of T-bet/Tbx21 to repress Pdcd1 transcription.
PD-L1 (show CD274 Antibodies) selectively enhances T cell-mediated immune responses, driving graft-versus-host disease lethality and suggesting a context-dependent function of the PD-1/PD-L1 (show CD274 Antibodies) axis
this study shows that PD-1 regulates early glycolytic and mitochondrial alterations in virus-specific CD8 (show CD8A Antibodies)+ T cells generated during infection, and represses transcriptional coactivator PGC-1alpha (show PPARGC1A Antibodies)
Our results suggest that anti-PD-1 antibody treatment has little effect on afatinib-induced lung injury.
both mouse and human tumour-associated macrophages (TAM (show CCNA1 Antibodies)) express PD-1; TAM (show CCNA1 Antibodies) PD-1 expression increases over time in mouse models of cancer and with increasing disease stage in primary human cancers
These data implicate a critical role for conserved region C (CR-C), a promoter proximal cis (show CISH Antibodies)-regulatory element that is critical to PD-1 expression in vitro, in governing PD-1 expression, and a subsequent role in guiding CD8 (show CD8A Antibodies) T cell differentiation
we provide evidence that indicates that the PD-1(+) fraction of DN T cells represents self-reactive cells.
PD-1 is overexpressed in IL-17A (show IL17A Antibodies)-producing T cells in both imiquimod-treated mice and patients with psoriasis. Moreover, recombinant PD-L1 (show CD274 Antibodies)-Fc alleviates psoriatic inflammation in imiquimod-treated mice.
May have a role in the regulation of spermatogenesis.
programmed cell death 1
, programmed cell death protein 1
, protein PD-1
, programmed death 1
, spermatogenesis associated PD1
, spermatogenesis-associated protein 2
, spermatogenesis-associated protein PD1