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May have a role in the regulation of spermatogenesis.. Additionally we are shipping PD-1 Proteins (87) and PD-1 Kits (18) and many more products for this protein.
Showing 10 out of 611 products:
Human Polyclonal PD-1 Primary Antibody for EIA, WB - ABIN401428
Zhong, Bai, Gao, Strom, Rothstein: Suppression of expression and function of negative immune regulator PD-1 by certain pattern recognition and cytokine receptor signals associated with immune system danger. in International immunology 2004
Show all 4 references for ABIN401428
Human Polyclonal PD-1 Primary Antibody for EIA, IHC (p) - ABIN500457
Holling, Schooten, van Den Elsen: Function and regulation of MHC class II molecules in T-lymphocytes: of mice and men. in Human immunology 2004
Show all 4 references for ABIN500457
Human Monoclonal PD-1 Primary Antibody for EIA, WB - ABIN263912
Freeman, Long, Iwai, Bourque, Chernova, Nishimura, Fitz, Malenkovich, Okazaki, Byrne, Horton, Fouser, Carter, Ling, Bowman, Carreno, Collins, Wood, Honjo: Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. in The Journal of experimental medicine 2000
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Human Polyclonal PD-1 Primary Antibody for ELISA, WB - ABIN185400
Nielsen, Laustrup, Voss, Junker, Husby, Lillevang: A putative regulatory polymorphism in PD-1 is associated with nephropathy in a population-based cohort of systemic lupus erythematosus patients. in Lupus 2004
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Mouse (Murine) Monoclonal PD-1 Primary Antibody for FACS - ABIN951271
Agata, Kawasaki, Nishimura, Ishida, Tsubata, Yagita, Honjo: Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes. in International immunology 1997
Show all 2 references for ABIN951271
Mouse (Murine) Monoclonal PD-1 Primary Antibody for FACS - ABIN951269
Ansari, Salama, Chitnis, Smith, Yagita, Akiba, Yamazaki, Azuma, Iwai, Khoury, Auchincloss, Sayegh: The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice. in The Journal of experimental medicine 2003
Show all 2 references for ABIN951269
Mouse (Murine) Polyclonal PD-1 Primary Antibody for FACS - ABIN4896838
Lee, Rigby, Zotos, Tsai, Kawamoto, Marshall, Ramiscal, Chan, Gatto, Brink, Yu, Fagarasan, Tarlinton, Cunningham, Vinuesa: B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells. in The Journal of experimental medicine 2011
We identify a novel protumorigenic PD-1(hi) B-cell subset in human HCC (show FAM126A Antibodies) that exhibits a phenotype distinct from that of peripheral regulatory B cells. TLR4 (show TLR4 Antibodies)-mediated BCL6 (show BCL6 Antibodies) upregulation is critical for induction of PD-1(hi) B cells, which operate via IL10 (show IL10 Antibodies)-dependent pathways upon interacting with PD-L1 (show CD274 Antibodies) to cause T-cell dysfunction and foster disease progression.
over-expression of PD-1 in subsets of vascular anomalies, while PD-L1 (show CD274 Antibodies) was negative
The results demonstrated significantly lower expression of PD-1 and PD-L1 (show CD274 Antibodies) in chronic ITP (show ITPA Antibodies) patients compared with healthy individuals.
Immune checkpoint proteins are co-inhibitory factors that can diminish the antigen-specific immune responses by attenuating the regulatory role of cytotoxic T-lymphocyte-associated protein 4 (show CTLA4 Antibodies), programmed cell death-1, lymphocyte-activation gene 3 (show LAG3 Antibodies), and T-cell immunoglobulin mucin-3 (show HAVCR2 Antibodies)
PD-1 may play a key role in the process of carcinogenesis of ESCC but not associated with prognosis and overall survival.
over-expression of EBI3 (show EBI3 Antibodies) could reduce the apoptosis of Treg/CD4 (show CD4 Antibodies)(+)T/CD8 (show CD8A Antibodies)(+)T cells and prevent radiation-induced immunosuppression of cervical cancer HeLa cells by inhibiting the activation of PD-1/PD-L1 (show CD274 Antibodies) signaling pathway
urther studies are necessary to explore the impact of EMT (show ITK Antibodies) on the tumour immune microenvironment and to identify potential biomarkers for selecting patients who might preferentially benefit from PD-1/PD-L1 (show CD274 Antibodies) blockade or immunotherapies more broadly.
The DNA methylation (show HELLS Antibodies) of both IFNgamma and PD1 increases the first 3 months after transplantation in memory CD8 (show CD8A Antibodies)+ T cells in kidney transplant recipients.
Soluble PD-1 may suppress the level of CD4 (show CD4 Antibodies)+CD25 (show IL2RA Antibodies) regulatory T cells in the peripheral blood of rheumatoid arthritis patients, and may be involved in a variety of immune processes mediated by CD4 (show CD4 Antibodies)+CD25 (show IL2RA Antibodies) regulatory T cells.
The expressions of PD-1 and PD-L1 (show CD274 Antibodies) may be associated with the occurrence and development of pulmonary carcinoids.
data defined PD-1(hi)IL-25R(hi) as an early checkpoint in Innate lymphoid cell development; results provide a perspective for exploring PD-1 and its ligand (PD-L1 (show CD274 Antibodies)) in immunotherapy, and allow effective manipulation of the immune system for disease prevention and therapy
Authors demonstrate that inactivation of the PD-1 gene in melanoma-reactive CD8 (show CD8A Antibodies)(+) T cells and in fibrosarcoma-reactive polyclonal T cells enhanced the persistence of PD-1 gene-modified T cells at the tumor site and increased tumor control.
PD-1/PD-L1 (show CD274 Antibodies) plays a crucial role in maintaining immune tolerance induced by UVB-iDCs, as well as in actively controlling effector T cells specific to alloantigens.
PD-1 dampens antigen-specific Th17 response, thus inhibiting autoimmune arthritis
Tim-3 (show HAVCR2 Antibodies)(+) PD-1(+) CD8 (show CD8A Antibodies)(+) T cells showed more evident properties associated with exhaustion than Tim-3 (show HAVCR2 Antibodies)(-) PD-1(+) CD8 (show CD8A Antibodies)(+) T cells.
that porcine islet-specific tolerance is dependent on PD-1, which could not be extended to skin grafts
Programmed cell death-1 engagement followed by zymosan stimulation might primarily attenuate the phosphorylation of tyrosine residue in Programmed cell death-1 receptor/ligand.
Study suggests that expression of the inhibitory receptors PD-1 and LAG-3 (show LAG3 Antibodies) on CD4 (show CD4 Antibodies)(+) T cells and their reduced IL-2 (show IL2 Antibodies) production are common characteristic features of Plasmodium infection.
these data suggest a scenario in which microglia are involved in the regulation of experimental autoimmune encephalomyelitis by suppressing Th1 (show HAND1 Antibodies)-cell differentiation via the PD-L1 (show CD274 Antibodies)-nitric oxide pathway.
Blockade of TGFbeta (show TGFB1 Antibodies) downregulated PD-1 and PD-L1 (show CD274 Antibodies) expression and precipitated graft rejection.
May have a role in the regulation of spermatogenesis.
programmed cell death 1
, programmed cell death protein 1
, protein PD-1
, programmed death 1
, spermatogenesis associated PD1
, spermatogenesis-associated protein 2
, spermatogenesis-associated protein PD1