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May have a role in the regulation of spermatogenesis.. Additionally we are shipping PD-1 Proteins (90) and PD-1 Kits (20) and many more products for this protein.
Showing 10 out of 631 products:
Human Polyclonal PD-1 Primary Antibody for ELISA (Detection), FACS - ABIN4899871
Sakthivel, Ramanujam, Wang, Pirskanen, Lefvert: Programmed Death-1: from gene to protein in autoimmune human myasthenia gravis. in Journal of neuroimmunology 2008
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Human Polyclonal PD-1 Primary Antibody for EIA, WB - ABIN401428
Zhong, Bai, Gao, Strom, Rothstein: Suppression of expression and function of negative immune regulator PD-1 by certain pattern recognition and cytokine receptor signals associated with immune system danger. in International immunology 2004
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Human Monoclonal PD-1 Primary Antibody for EIA, WB - ABIN263912
Freeman, Long, Iwai, Bourque, Chernova, Nishimura, Fitz, Malenkovich, Okazaki, Byrne, Horton, Fouser, Carter, Ling, Bowman, Carreno, Collins, Wood, Honjo: Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. in The Journal of experimental medicine 2000
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Human Polyclonal PD-1 Primary Antibody for ELISA, WB - ABIN185400
Nielsen, Laustrup, Voss, Junker, Husby, Lillevang: A putative regulatory polymorphism in PD-1 is associated with nephropathy in a population-based cohort of systemic lupus erythematosus patients. in Lupus 2004
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Mouse (Murine) Polyclonal PD-1 Primary Antibody for FACS, IHC - ABIN4899873
Kasagi, Kawano, Okazaki, Honjo, Morinobu, Hatachi, Shimatani, Tanaka, Minato, Kumagai: Anti-programmed cell death 1 antibody reduces CD4+PD-1+ T cells and relieves the lupus-like nephritis of NZB/W F1 mice. in Journal of immunology (Baltimore, Md. : 1950) 2010
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Mouse (Murine) Monoclonal PD-1 Primary Antibody for FACS - ABIN951271
Agata, Kawasaki, Nishimura, Ishida, Tsubata, Yagita, Honjo: Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes. in International immunology 1997
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Mouse (Murine) Monoclonal PD-1 Primary Antibody for FACS - ABIN951270
Ansari, Salama, Chitnis, Smith, Yagita, Akiba, Yamazaki, Azuma, Iwai, Khoury, Auchincloss, Sayegh: The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice. in The Journal of experimental medicine 2003
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Mouse (Murine) Polyclonal PD-1 Primary Antibody for FACS - ABIN4896838
Lee, Rigby, Zotos, Tsai, Kawamoto, Marshall, Ramiscal, Chan, Gatto, Brink, Yu, Fagarasan, Tarlinton, Cunningham, Vinuesa: B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells. in The Journal of experimental medicine 2011
In cutaneous diffuse large b-cell lymphoma, a considerable proportion of CD33 (show CD33 Antibodies)(+) myeloid-derived suppressor cells (MDSCs) with PD-L1 (show CD274 Antibodies) coexpression was admixed. Tumor cells expressed CD33 (show CD33 Antibodies) to variable degrees (2% to 60%). We propose that PD-L1 (show CD274 Antibodies)(+) tumor cells and PD-L1 (show CD274 Antibodies)(+) MDSCs shield the tumor against PD-1(+) tumor-infiltrating lymphocytes, consequently leading to inhibition and diminution of tumor-infiltrating lymphocytes.
Autoimmune hepatitis (AIH) AIH patients with active disease and incomplete response to standard treatment have similarly increased sPD (show HOXD13 Antibodies)-1 levels. AIH patients have increased ability to up-regulate PD-1 following in vitro activation.
All anaplastic thyroid cancer samples demonstrated PD-1 expression in inflammatory cells whereas tumor cells were primarily negative.
PD-1 and PD-L1 (show CD274 Antibodies) are highly expressed by most small intestinal adenocarcinomas.
The data reveal SPATA2 (show SPATA2 Antibodies) as a high-affinity binding partner of CYLD (show CYLD Antibodies) and HOIP (show RNF31 Antibodies), and a regulatory component of linear ubiquitin chain assembly complex-mediated NF-kappaB (show NFKB1 Antibodies) signaling.
both mouse and human tumour-associated macrophages (TAM (show CCNA1 Antibodies)) express PD-1; TAM (show CCNA1 Antibodies) PD-1 expression increases over time in mouse models of cancer and with increasing disease stage in primary human cancers
This study shows that only PDCD1/rs2227981 contributes to the genetic susceptibility of SO, and that the other 23 susceptibility loci of VKH disease are probably not involved in the pathogenesis of this disease.
In sepsis, reducted neutrophil and monocyte function correlated with PD-1 expression on CD8 (show CD8A Antibodies)(+) T cells and NK cells. Antibodies against PD-1 restored function in neutrophil, monocyte, T cells, and NK cells, showing the impact of the PD-1:PD-L1 (show CD274 Antibodies) axis in sepsis-immune suppression.
PD-L1 (show CD274 Antibodies)/PD-1 are expressed in neoplastic and nonneoplastic thymus and do not appear to modulate the presence of CD4 (show CD4 Antibodies)/CD8 (show CD8A Antibodies) positive lymphocytes.
our data suggest a novel immune metabolic PD-L1 (show CD274 Antibodies)/PD-1-mediated crosstalk between CLL cells and monocytes, hampering their function and potentially limiting the efficacy of antibody-based therapeutic approaches.
Our results suggest that anti-PD-1 antibody treatment has little effect on afatinib-induced lung injury.
These data implicate a critical role for conserved region C (CR-C), a promoter proximal cis (show CISH Antibodies)-regulatory element that is critical to PD-1 expression in vitro, in governing PD-1 expression, and a subsequent role in guiding CD8 (show CD8A Antibodies) T cell differentiation
we provide evidence that indicates that the PD-1(+) fraction of DN T cells represents self-reactive cells.
PD-1 is overexpressed in IL-17A (show IL17A Antibodies)-producing T cells in both imiquimod-treated mice and patients with psoriasis. Moreover, recombinant PD-L1 (show CD274 Antibodies)-Fc alleviates psoriatic inflammation in imiquimod-treated mice.
PD-1 receptor has a role in interacting with programmed cell death ligands and B7-1 (show CD80 Antibodies)
PD-1 is upregulated in CD4 (show CD4 Antibodies)+ T cells in Schistosoma japonicum (S. japonicum)-infected mice.
Findings indicated that METH (show MTRR Antibodies) induced the upregulation of PD-1 expression which altered the cytokine production as well as cytotoxic functions in mouse model of lymphocytic choriomeningitis virus infection.
Taken together, our data demonstrate the importance of CD40 (show CD40 Antibodies) signaling in the conversion of CTL exhaustion and its ability to enhance PD-1 antagonist action in rescuing exhausted CTLs in chronic infection.
Our proteogenomic analysis demonstrates a role of Smad4 (show SMAD4 Antibodies) loss in the PD-L1 (show CD274 Antibodies) immune evasion, as well as Il1rl1 (show IL1RL1 Antibodies)'s role in CSC-like properties of NCC (show SLC12A3 Antibodies)-S1M.
May have a role in the regulation of spermatogenesis.
programmed cell death 1
, programmed cell death protein 1
, protein PD-1
, programmed death 1
, spermatogenesis associated PD1
, spermatogenesis-associated protein 2
, spermatogenesis-associated protein PD1