Programmed Cell Death 1 Proteins (PDCD1)

May have a role in the regulation of spermatogenesis.. Additionally we are shipping PD-1 Antibodies (642) and PD-1 Kits (22) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PDCD1 5133 Q15116
PDCD1 18566 Q02242
PDCD1 301626  
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Top PD-1 Proteins at antibodies-online.com

Showing 10 out of 96 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Mouse Fc Tag,His tag 100 μg Log in to see 20 to 21 Days
$250.80
Details
HOST_HEK-293 Cells Human His tag,Fc Tag,Biotin The purity of Biotinylated Human PD-1, His Tag & FC tag was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue. 5 μg Log in to see 2 to 3 Days
$200.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_HEK-293 Cells Mouse His tag 50 μg Log in to see 2 to 3 Days
$695.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag 0.05 mg Log in to see 2 to 3 Days
$275.00
Details
HOST_HEK-293 Cells Human His tag Human PD-1, His Tag (HPLC-verified) on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. Immobilized Human PD-1, His Tag  with a linear range of 0.31-1.25 μg/mL. 100 μg Log in to see 2 to 3 Days
$330.00
Details
HOST_Human Cells Human Fc Tag,His tag 100 μg Log in to see 20 to 21 Days
$382.80
Details

PDCD1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , , , ,
, , , , , , , , , , , , , , , , , ,
Mouse (Murine) , , , , , ,
, , , , , , ,
Rat (Rattus) , ,
, , ,

Top referenced PD-1 Proteins

  1. Human PD-1 Protein expressed in Wheat germ - ABIN1314407 : Matsumoto, Miyake, Matsushita, Ohnishi, Ikeda, Shiraha, Takaki, Nouso, Yamamoto: Anti-programmed cell death-1 antibody as a new serological marker for type 1 autoimmune hepatitis. in Journal of gastroenterology and hepatology 2013 (PubMed)
    Show all 2 references for 1314407

  2. Mouse (Murine) PD-1 Protein expressed in Human Cells - ABIN2007359 : Prodeus, Abdul-Wahid, Fischer, Huang, Cydzik, Gariépy: Targeting the PD-1/PD-L1 Immune Evasion Axis With DNA Aptamers as a Novel Therapeutic Strategy for the Treatment of Disseminated Cancers. in Molecular therapy. Nucleic acids 2015 (PubMed)

More Proteins for Programmed Cell Death 1 (PDCD1) Interaction Partners

Human Programmed Cell Death 1 (PDCD1) interaction partners

  1. PD-1 is required for maintaining the number, and hence function, of KLRG1 (show KLRG1 Proteins)(+) Group 2 innate lymphoid cells.

  2. In cutaneous diffuse large b-cell lymphoma, a considerable proportion of CD33 (show CD33 Proteins)(+) myeloid-derived suppressor cells (MDSCs) with PD-L1 (show CD274 Proteins) coexpression was admixed. Tumor cells expressed CD33 (show CD33 Proteins) to variable degrees (2% to 60%). We propose that PD-L1 (show CD274 Proteins)(+) tumor cells and PD-L1 (show CD274 Proteins)(+) MDSCs shield the tumor against PD-1(+) tumor-infiltrating lymphocytes, consequently leading to inhibition and diminution of tumor-infiltrating lymphocytes.

  3. Autoimmune hepatitis (AIH) AIH patients with active disease and incomplete response to standard treatment have similarly increased sPD (show HOXD13 Proteins)-1 levels. AIH patients have increased ability to up-regulate PD-1 following in vitro activation.

  4. All anaplastic thyroid cancer samples demonstrated PD-1 expression in inflammatory cells whereas tumor cells were primarily negative.

  5. PD-1 and PD-L1 (show CD274 Proteins) are highly expressed by most small intestinal adenocarcinomas.

  6. both mouse and human tumour-associated macrophages (TAM (show CCNA1 Proteins)) express PD-1; TAM (show CCNA1 Proteins) PD-1 expression increases over time in mouse models of cancer and with increasing disease stage in primary human cancers

  7. The data reveal SPATA2 (show SPATA2 Proteins) as a high-affinity binding partner of CYLD (show CYLD Proteins) and HOIP (show RNF31 Proteins), and a regulatory component of linear ubiquitin chain assembly complex-mediated NF-kappaB (show NFKB1 Proteins) signaling.

  8. This study shows that only PDCD1/rs2227981 contributes to the genetic susceptibility of SO, and that the other 23 susceptibility loci of VKH disease are probably not involved in the pathogenesis of this disease.

  9. In sepsis, reducted neutrophil and monocyte function correlated with PD-1 expression on CD8 (show CD8A Proteins)(+) T cells and NK cells. Antibodies against PD-1 restored function in neutrophil, monocyte, T cells, and NK cells, showing the impact of the PD-1:PD-L1 (show CD274 Proteins) axis in sepsis-immune suppression.

  10. PD-L1 (show CD274 Proteins)/PD-1 are expressed in neoplastic and nonneoplastic thymus and do not appear to modulate the presence of CD4 (show CD4 Proteins)/CD8 (show CD8A Proteins) positive lymphocytes.

Mouse (Murine) Programmed Cell Death 1 (PDCD1) interaction partners

  1. PD-1 is required for maintaining the number, and hence function, of KLRG1 (show KLRG1 Proteins)(+) Group 2 innate lymphoid cells.

  2. this study shows that PD-1 regulates early glycolytic and mitochondrial alterations in virus-specific CD8+ T cells generated during infection, and represses transcriptional coactivator PGC-1alpha

  3. Our results suggest that anti-PD-1 antibody treatment has little effect on afatinib-induced lung injury.

  4. both mouse and human tumour-associated macrophages (TAM (show CCNA1 Proteins)) express PD-1; TAM (show CCNA1 Proteins) PD-1 expression increases over time in mouse models of cancer and with increasing disease stage in primary human cancers

  5. These data implicate a critical role for conserved region C (CR-C), a promoter proximal cis (show CISH Proteins)-regulatory element that is critical to PD-1 expression in vitro, in governing PD-1 expression, and a subsequent role in guiding CD8 (show CD8A Proteins) T cell differentiation

  6. we provide evidence that indicates that the PD-1(+) fraction of DN T cells represents self-reactive cells.

  7. PD-1 is overexpressed in IL-17A (show IL17A Proteins)-producing T cells in both imiquimod-treated mice and patients with psoriasis. Moreover, recombinant PD-L1 (show CD274 Proteins)-Fc alleviates psoriatic inflammation in imiquimod-treated mice.

  8. PD-1 receptor has a role in interacting with programmed cell death ligands and B7-1 (show CD80 Proteins)

  9. PD-1 is upregulated in CD4 (show CD4 Proteins)+ T cells in Schistosoma japonicum (S. japonicum)-infected mice.

  10. Findings indicated that METH (show MTRR Proteins) induced the upregulation of PD-1 expression which altered the cytokine production as well as cytotoxic functions in mouse model of lymphocytic choriomeningitis virus infection.

PD-1 (PDCD1) Protein Profile

Protein Summary

May have a role in the regulation of spermatogenesis.

Gene names and symbols associated with PDCD1

  • programmed cell death 1 (PDCD1)
  • programmed cell death 1 (Pdcd1)
  • spermatogenesis associated 2 (SPATA2)
  • CD279 protein
  • hPD-1 protein
  • hPD-l protein
  • Ly101 protein
  • PD-1 protein
  • PD1 protein
  • Pdc1 protein
  • SLEB2 protein
  • tamo protein

Protein level used designations for PDCD1

programmed cell death 1 , programmed cell death protein 1 , protein PD-1 , programmed death 1 , mPD-1 , spermatogenesis associated PD1 , spermatogenesis-associated protein 2 , spermatogenesis-associated protein PD1

GENE ID SPECIES
424913 Gallus gallus
5133 Homo sapiens
486213 Canis lupus familiaris
613842 Bos taurus
18566 Mus musculus
301626 Rattus norvegicus
9825 Homo sapiens
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