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anti-Programmed Cell Death 4 (Neoplastic Transformation Inhibitor) (PDCD4) Antibodies

PDCD4 is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Additionally we are shipping PDCD4 Kits (13) and PDCD4 Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PDCD4 18569 Q61823
PDCD4 64031 Q9JID1
PDCD4 27250 Q53EL6
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Top anti-PDCD4 Antibodies at antibodies-online.com

Showing 10 out of 234 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB PDCD4 Antibody (Center) (ABIN657922) western blot analysis in HL-60 cell line lysates (35 µg/lane). This demonstrates the PDCD4 antibody detected the PDCD4 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$229.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PDCD4 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Jurkat cell lysate Host: Rabbit  Target Name: PDCD4  Sample Tissue: HepG2Lane A:  Primary Antibody Lane B:  Primary Antibody + Blocking Peptide Primary Antibody Concentration: 2.0 µg/mL Peptide Concentration:..0 µg/mL Lysate Quantity:.41 µg/laneGel Concentration: 12 % 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from 293 cells treated with serum 20% 15', using PDCD4 (Phospho-Ser457) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain, using PDCD4 (Phospho-Ser457) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HuvEc cells, K562 cells and COS-7 cells, using PDCD4 (Phospho-Ser67) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry of PDCD4 in mouse brain tissue with this product at 2.5 μg/ml. Western blot analysis of PDCD4 in A-20 cell lysate with this product at (A) 0.5 and (B) 1μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Mouse Biotin IHC, ELISA, WB Western Blot of Mouse anti-Pdcd4 phospho S457 Biotin Conjugated antibody. Lane 1: Pdcd4 recombinant protein. Lane 2: none. Load: 100 ng per lane. Primary antibody: Pdcd4 phospho S457 Biotin Conjugated antibody at 1:1,000 for overnight at 4°C. Secondary antibody: HRP Streptavidin secondary antibody at 1:40,000 for 30 min at RT. Block: MB-070 for 30 min at RT. Predicted/Observed size: 50 kDa, 50 kDa for Pdcd4 phospho S457. Other band(s): Pdcd4 phospho S457 splice variants and isoforms 50 μg Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from 293 cells, using PDCD4 (Ab-457) Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of HeLa cells, using PDCD4 (Ab-457) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated EIA, IHC (fro), IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$500.50
Details

PDCD4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-PDCD4 Antibodies

  1. Human Polyclonal PDCD4 Primary Antibody for EIA, IHC (p) - ABIN500461 : Göke, Barth, Schmidt, Samans, Lankat-Buttgereit: Programmed cell death protein 4 suppresses CDK1/cdc2 via induction of p21(Waf1/Cip1). in American journal of physiology. Cell physiology 2004 (PubMed)
    Show all 4 references for ABIN500461

  2. Cow (Bovine) Polyclonal PDCD4 Primary Antibody for WB - ABIN2792230 : Yang, Cho, Zakowicz, Hegamyer, Sonenberg, Colburn: A novel function of the MA-3 domains in transformation and translation suppressor Pdcd4 is essential for its binding to eukaryotic translation initiation factor 4A. in Molecular and cellular biology 2004 (PubMed)
    Show all 3 references for ABIN2792230

  3. Human Monoclonal PDCD4 Primary Antibody for EIA, IHC (fro) - ABIN400797 : Huang, Wu, Loeb, Hsu, Heidersbach, Brincat, Horiuchi, Lebbink, Mo, Goga, McManus: Up-regulation of miR-21 by HER2/neu signaling promotes cell invasion. in The Journal of biological chemistry 2009 (PubMed)
    Show all 3 references for ABIN400797

  4. Human Monoclonal PDCD4 Primary Antibody for IHC, ELISA - ABIN1043755 : Jansen, Camalier, Colburn: Epidermal expression of the translation inhibitor programmed cell death 4 suppresses tumorigenesis. in Cancer research 2005 (PubMed)
    Show all 2 references for ABIN1043755

  5. Human Polyclonal PDCD4 Primary Antibody for IF, ELISA - ABIN1532754 : Deloukas, Earthrowl, Grafham, Rubenfield, French, Steward, Sims, Jones, Searle, Scott, Howe, Hunt, Andrews, Gilbert, Swarbreck, Ashurst, Taylor, Battles, Bird, Ainscough, Almeida, Ashwell, Ambrose et al.: The DNA sequence and comparative analysis of human chromosome 10. ... in Nature 2004 (PubMed)

  6. Human Monoclonal PDCD4 Primary Antibody for EIA, IHC (p) - ABIN317548 : Palamarchuk, Efanov, Maximov, Aqeilan, Croce, Pekarsky: Akt phosphorylates and regulates Pdcd4 tumor suppressor protein. in Cancer research 2005 (PubMed)

  7. Human Polyclonal PDCD4 Primary Antibody for WB - ABIN2774608 : Yang, Matthews, Clair, Wang, Baker, Li, Tan, Colburn: Tumorigenesis suppressor Pdcd4 down-regulates mitogen-activated protein kinase kinase kinase kinase 1 expression to suppress colon carcinoma cell invasion. in Molecular and cellular biology 2006 (PubMed)

  8. Human Polyclonal PDCD4 Primary Antibody for IHC (p), WB - ABIN657922 : Hayashi, Aishima, Miyasaka, Nakata, Morimatsu, Oda, Nagai, Oda, Tanaka, Tsuneyoshi: Pdcd4 expression in intraductal papillary mucinous neoplasm of the pancreas: its association with tumor progression and proliferation. in Human pathology 2010 (PubMed)

More Antibodies against PDCD4 Interaction Partners

Mouse (Murine) Programmed Cell Death 4 (Neoplastic Transformation Inhibitor) (PDCD4) interaction partners

  1. PDCD4 serves as an important regulator of keratinocytes proliferation and contact inhibition in vitro.

  2. In conclusion, miR (show MLXIP Antibodies)-21 is sensitive to high-concentration glucose treatment in macrophages, and appears to have a protective effect in macrophage apoptosis induced by high concentrations of glucose via PDCD4.

  3. atheroprotective unidirectional pulsatile shear stress affects the expression of PDCD4 in endothelial cells

  4. we demonstrate that miR (show MLXIP Antibodies)-21 regulates T-cell acute lymphoblastic leukemia cell survival via repression of the tumor suppressor Pdcd4.

  5. Dual expression of shAkt1 and Pdcd4 effectively suppresses lung tumorigenesis

  6. miR (show MLXIP Antibodies)-21 is endowed with anti-apoptotic properties by suppressing the expression of PDCD4 gene and active caspase 3 (show CASP3 Antibodies)/8 fragments in the condition of renal IRI

  7. sulforaphane protects PDCD4 downregulation posed by pro-inflammatory stimuli through modulating both transcription and proteolysis via controlling Akt1 (show AKT1 Antibodies) and/or S6K1 (show RPS6KB1 Antibodies) activities in RAW 264.7 cells

  8. these findings support the existence of a microRNA-21-responsive PDCD4/caspase-3 (show CASP3 Antibodies) pathway in the pulmonary tissues that when active serves to promote endothelial apoptosis in vitro and pulmonary hypertension in vivo.

  9. we demonstrated that the miR (show MLXIP Antibodies)-21-PDCD4 signaling was involved in the cellular responses to UVB in a mouse epidermal cell line

  10. during bacterial pneumonia IFNlambda promotes inflammation by inhibiting miR (show MLXIP Antibodies)-21 regulation of PDCD4.

Human Programmed Cell Death 4 (Neoplastic Transformation Inhibitor) (PDCD4) interaction partners

  1. PDCD4 inhibits cell growth through PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) signaling in non-small cell lung cancer.

  2. This study describes the regulation of PDCD4 specifically in tonsil SCC (show CYP11A1 Antibodies) by miR (show MLXIP Antibodies)-499 and miR (show MLXIP Antibodies)-21 and has documented the loss of PDCD4 in oropharyngeal squamous cell carcinoma

  3. Unprecedentedly, HuR (show ELAVL1 Antibodies) was also found to bind to miR (show MLXIP Antibodies)-21 directly, preventing its interaction with the PDCD4 3'-UTR (show UTS2R Antibodies), thereby preventing the translation repression of PDCD4.

  4. miR (show MLXIP Antibodies)-21 has a role in upregulating PTEN (show PTEN Antibodies), RECK (show RECK Antibodies) and PDCD4 in glioma

  5. PDGF (show PDGFA Antibodies)-BB stimulates cell proliferation through microRNA-21-mediated PDCD4 down-regulation, leading to the development of TAO.

  6. Results indicated that PDCD4 may be a novel candidate of tumor suppressor gene in hepatocellular carcinoma and that promoter hypermethylation is an important mechanism for its downregulation and a good predictor of survival.

  7. These findings suggest that miR (show MLXIP Antibodies)-21 and PDCD4 might be potential biomarkers for malignant melanoma and might provide treatment targets in the future.

  8. We propose that SRSF3 (show SRSF3 Antibodies) could act as a coordinator of the expression of PDCD4 protein via two mechanisms on two alternatively spliced mRNA isoforms.

  9. Low PDCD4 increases osteosarcoma cells resistance to apoptosis.

  10. These findings support the feasibility of future efforts for diagnosis and gene therapy for prostate cancer that are based on IL-6 (show IL6 Antibodies), miR (show MLXIP Antibodies)-21, and PDCD4.

PDCD4 Antigen Profile

Protein Summary

This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with PDCD4

  • programmed cell death 4 (neoplastic transformation inhibitor) (pdcd4) antibody
  • programmed cell death 4 (neoplastic transformation inhibitor) (PDCD4) antibody
  • programmed cell death 4 (Pdcd4) antibody
  • D19Ucla1 antibody
  • Dug antibody
  • H731 antibody
  • Ma3 antibody
  • MGC69337 antibody
  • PDCD4 antibody
  • Tis antibody

Protein level used designations for PDCD4

programmed cell death 4 (neoplastic transformation inhibitor) , programmed cell death protein 4 , programmed cell death protein 4-like , protein MA-3 , topoisomerase-inhibitor suppressed protein , death up-regulated gene protein , death-upregulated , neoplastic transformation inhibitor protein , nuclear antigen H731 , protein 197/15a , protein I11/6

GENE ID SPECIES
407925 Xenopus (Silurana) tropicalis
450735 Pan troglodytes
695345 Macaca mulatta
100021762 Monodelphis domestica
100080517 Ornithorhynchus anatinus
100354557 Oryctolagus cuniculus
100413000 Callithrix jacchus
100469480 Ailuropoda melanoleuca
100584426 Nomascus leucogenys
18569 Mus musculus
64031 Rattus norvegicus
27250 Homo sapiens
380222 Xenopus laevis
374191 Gallus gallus
477818 Canis lupus familiaris
506724 Bos taurus
100157112 Sus scrofa
100173014 Pongo abelii
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