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The protein encoded by Prok1 induces proliferation, migration, and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Additionally we are shipping Prokineticin 1 Kits (54) and Prokineticin 1 Proteins (19) and many more products for this protein.
Showing 10 out of 66 products:
Human Polyclonal Prokineticin 1 Primary Antibody for FACS, IHC - ABIN347051
Hoffmann, Feige, Alfaidy: Expression and oxygen regulation of endocrine gland-derived vascular endothelial growth factor/prokineticin-1 and its receptors in human placenta during early pregnancy. in Endocrinology 2006
Human Polyclonal Prokineticin 1 Primary Antibody for EIA, IHC (fro) - ABIN1108741
Brouillet, Hoffmann, Chauvet, Salomon, Chamboredon, Sergent, Benharouga, Feige, Alfaidy: Revisiting the role of hCG: new regulation of the angiogenic factor EG-VEGF and its receptors. in Cellular and molecular life sciences : CMLS 2012
important role for PK-1 in luteal function by acting as a mitogen and survival factor in corpus luteum derived endothelial cells
PROK1, acting via PROKR1 (show PROKR1 Antibodies), may be involved in the recruitment of monocytes to regressing CL
EG-VEGF/PK1 and Bv8/PK2 (show PROK2 Antibodies) thus represent new regulatory peptides acting as autocrine mitogens for endocrine cells
Data suggest that prokineticins (PROK1 and PROK2 (show PROK2 Antibodies)) and prokineticin receptors (PROKR1 (show PROKR1 Antibodies) and PROKR2 (show PROKR2 Antibodies)) act as main regulators of physiological functions of ovary, uterus, placenta, and testis. [REVIEW]
EG-VEGF and its receptor PKR1 (show PROKR1 Antibodies) might play a role in the pathogenesis of adrenocortical tumors and could serve as prognostic markers for this rare malignant disease.
The prognosis was poorer in colorectal cancers that expressed both PROK1 and VEGF relative to the cases that expressed only 1 protein, and the expression of both proteins was found to be an independent prognostic factor.
PROK1 levels in follicular fluid and fertilization culture media could constitute new predictive noninvasive markers of successful embryo implantation in conventional in vitro fertilization-embryo transfer
Simultaneous targeting of both angiogenic growth factors (VEGF (show VEGFA Antibodies)/PROK1) may prove more useful in colorectal cancer
High Prokineticin 1 protein expression is associated with sporadic colorectal cancer.
Expression of PROK1 and PROKR1 (show PROKR1 Antibodies) was significantly higher in mid-gestation ovaries (17-20 wk) than at earlier gestations (8-11 and 14-16 wk).
EG-VEGF, BV8 (show PROK2 Antibodies), and PROKR2 (show PROKR2 Antibodies) gene expression is approximately five, four, and two times higher in cystic fibrosis (show S100A8 Antibodies) lungs compared with controls.
More importantly this paper argues for EG-VEGF clinical relevance as a potential biomarker of the onset of pregnancy pathologies and discusses its potential usefulness for future therapeutic directions.
EG-VEGF and VEGFA (show VEGFA Antibodies) systems shared several canonical signaling pathways that may contribute to gene-gene interactions, including the Akt (show AKT1 Antibodies), IL-8 (show IL8 Antibodies), EGFR (show EGFR Antibodies), MAPK (show MAPK1 Antibodies), SRC (show SRC Antibodies), VHL (show VHL Antibodies), HIF-1A (show HIF1A Antibodies) and STAT3 (show STAT3 Antibodies).
EG-VEGF is a new mediator of PPARgamma (show PPARG Antibodies) effects during pregnancy and bring new insights into the fine mechanism of trophoblast invasion.
Bv8 (show PROK2 Antibodies) and EG-VEGF, along with other factors such as VEGF-A (show VEGFA Antibodies), may maintain the integrity and also regulate proliferation of the blood vessels in the testis
This is the first report demonstrating that Prok-1 acts as a gut (show GUSB Antibodies) mucosa/mesenchyme-derived factor and maintains proliferation and differentiation of enteric neural crest cells.
EG-VEGF was mainly localised in the labyrinth in mouse placenta. It may have direct effect on both endothelial & trophoblastic cells & is likely to play an important role in mouse placentation.
Prokineticin-1 (Prok-1) works coordinately with glial cell line-derived neurotrophic factor (GDNF (show GDNF Antibodies)) to mediate proliferation and differentiation of enteric neural crest cells.
The protein encoded by this gene induces proliferation, migration, and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. It has little or no effect on a variety of other endothelial and non-endothelial cell types. Its expression is restricted to the steroidogenic glands (ovary, testis, adrenal, and placenta), is induced by hypoxia, and often complementary to the expression of vascular endothelial growth factor (VEGF), suggesting that these molecules function in a coordinated manner.
, black mamba toxin-related protein
, endocrine-gland-derived vascular endothelial growth factor