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PA2G4 encodes an RNA-binding protein that is involved in growth regulation. Additionally we are shipping Proliferation-Associated 2G4, 38kDa Kits (12) and Proliferation-Associated 2G4, 38kDa Proteins (12) and many more products for this protein.
Showing 10 out of 83 products:
Human Polyclonal PA2G4 Primary Antibody for EIA, WB - ABIN452929
Zhang, Linn, Liu, Melamed, Tavora, Young, Burger, Hamburger: EBP1, an ErbB3-binding protein, is decreased in prostate cancer and implicated in hormone resistance. in Molecular cancer therapeutics 2008
Show all 3 references for ABIN452929
Human Polyclonal PA2G4 Primary Antibody for FACS, IHC (p) - ABIN389363
Okada, Jang, Ye: Ebp1 association with nucleophosmin/B23 is essential for regulating cell proliferation and suppressing apoptosis. in The Journal of biological chemistry 2007
Show all 2 references for ABIN389363
Cow (Bovine) Polyclonal PA2G4 Primary Antibody for WB - ABIN2783042
Zhang, Wang, Jelovac, Nakanishi, Yu, Akinmade, Goloubeva, Ross, Brodie, Hamburger: The ErbB3-binding protein Ebp1 suppresses androgen receptor-mediated gene transcription and tumorigenesis of prostate cancer cells. in Proceedings of the National Academy of Sciences of the United States of America 2005
These results strongly suggest that PA2G4 may have an important role on the regulation of DNA replication in eukaryotic cells.
Ebp1 (show NFKB1 Antibodies) p42 (show EPB42 Antibodies) isoform regulates the proteasomal degradation of the p85 (show ECM1 Antibodies) regulatory subunit of PI3K by recruiting a chaperone-E3 ligase complex HSP70 (show HSP70 Antibodies)/CHIP.
EBP1 (show NFKB1 Antibodies) is a novel component of the ZFP809-TRIM28 (show TRIM28 Antibodies) silencing complex to restrict the moloney murine leukemia virus replication in embryonic cells.
Ebp1 (show NFKB1 Antibodies) has a role in the regulation of embryonic muscle progenitors and adult muscle stem cells, which likely operates independently of ErbB3 (show ERBB3 Antibodies) signaling
EBP1 (show NFKB1 Antibodies) is in the cytoplasm & nucleolus. Nucleolar localization requires AA sequences at the NH2- and COOH-ends. Overexpression inhibits proliferation of human fibroblasts. It is part of RNP (show RNPC3 Antibodies) complexes & associates with different rRNAs.
IGF-1 (show IGF1 Antibodies) production and IGBP-3 and 4 protein levels were reduced in both embryo fibroblasts and adult knock-out mice. The proliferation of fibroblasts derived from Day 12.5 knock out embryos was also decreased as compared to that of wild type cells.
The combined determination of Ebp1 (show NFKB1 Antibodies) and p53 (show TP53 Antibodies) expression levels in cervical cancer patients could support the effective prediction of metastatic potential and patient prognosis.
Data highlight the tissue specificity function of EBP1 (show NFKB1 Antibodies) isoforms and show that only the oncogene (show RAB1A Antibodies) p48 (show IRF9 Antibodies) activates MHC II expression in human solid tumors, via STAT1 (show STAT1 Antibodies) phosphorylation, in order to affect tumor progression by triggering specific immune response.
Our results suggest a novel function of Ebp1 (show NFKB1 Antibodies) as a binding protein and negative regulator of Anxa2 (show ANXA2 Antibodies). The functional association between Anxa2 (show ANXA2 Antibodies) and EBP1 (show NFKB1 Antibodies) may participate in regulating cancer cell proliferation and invasion, contributing to cancer progression.
Ebp1 (show NFKB1 Antibodies) functionality is independent from heat-shock-protein-regulated progression networks in prostate cancer.
EBP1 (show NFKB1 Antibodies) participates in the regulation of intestinal inflammation via mediating Akt (show AKT1 Antibodies) signaling pathway.
Data suggest that inhibiting ErbB3-binding protein 1 Ebp1 phosphorylation may be an effective mechanism for inhibiting T-cell activation and proliferation.
Ebp1 (show NFKB1 Antibodies) p42 (show EPB42 Antibodies) isoform regulates the proteasomal degradation of the p85 regulatory subunit of PI3K (show PIK3CA Antibodies) by recruiting a chaperone-E3 ligase complex HSP70 (show HSP70 Antibodies)/CHIP.
data suggest that Vpr may inhibit Ebp1 (show NFKB1 Antibodies) to stabilize p53 (show TP53 Antibodies), which in turn leads to G2 arrest and apoptosis in U87MG cells
The major effect of EBP1 (show NFKB1 Antibodies) on ErbB2 (show ERBB2 Antibodies) mRNA expression levels is at the transcriptional level.
Down-regulation of the ErbB3 binding protein 1 in human bladder cancer promotes tumor progression and cell proliferation.
This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified.
proliferation-associated 2G4, 38kDa
, ErbB3-binding protein 1
, proliferation-associated protein 2G4
, proliferation-associated protein 2G4-like
, similar to proliferation-associated 2G4, 38kD
, DNA-binding factor KBF1
, nuclear factor NF-kappa-B p105 subunit
, nuclear factor of kappa light chain gene enhancer in B-cells 1, p105
, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105
, IRES-specific cellular trans-acting factor 45 kDa
, proliferation-associated 2G4, 38kD
, proliferation-associated protein 1
, protein p38-2G4
, ErbB-3 binding protein 1
, ErbB3-binding protein Ebp1
, cell cycle protein p38-2G4 homolog
, erbB3-binding protein 1