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Proliferation-Associated 2G4, 38kDa Proteins (PA2G4)

PA2G4 encodes an RNA-binding protein that is involved in growth regulation. Additionally we are shipping Proliferation-Associated 2G4, 38kDa Antibodies (81) and Proliferation-Associated 2G4, 38kDa Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat PA2G4 PA2G4 81736  
PA2G4 18813 P50580
PA2G4 5036 Q9UQ80
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Top Proliferation-Associated 2G4, 38kDa Proteins at antibodies-online.com

Showing 8 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$286.00
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 16 Days
$327.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$322.14
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details
Human Un-conjugated   5 μg Log in to see 6 Days
$168.54
Details

PA2G4 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

Top referenced Proliferation-Associated 2G4, 38kDa Proteins

  1. Human PA2G4 Protein expressed in Escherichia coli (E. coli) - ABIN666989 : Lamartine, Seri, Cinti, Heitzmann, Creaven, Radomski, Jost, Lenoir, Romeo, Sylla: Molecular cloning and mapping of a human cDNA (PA2G4) that encodes a protein highly homologous to the mouse cell cycle protein p38-2G4. in Cytogenetics and cell genetics 1997 (PubMed)
    Show all 2 references for ABIN666989

More Proteins for Proliferation-Associated 2G4, 38kDa (PA2G4) Interaction Partners

Xenopus laevis Proliferation-Associated 2G4, 38kDa (PA2G4) interaction partners

  1. These results strongly suggest that PA2G4 may have an important role on the regulation of DNA replication in eukaryotic cells.

Mouse (Murine) Proliferation-Associated 2G4, 38kDa (PA2G4) interaction partners

  1. Ebp1 (show NFKB1 Proteins) p42 (show EPB42 Proteins) isoform regulates the proteasomal degradation of the p85 (show ECM1 Proteins) regulatory subunit of PI3K by recruiting a chaperone-E3 ligase complex HSP70 (show HSP70 Proteins)/CHIP.

  2. EBP1 (show NFKB1 Proteins) is a novel component of the ZFP809-TRIM28 (show TRIM28 Proteins) silencing complex to restrict the moloney murine leukemia virus replication in embryonic cells.

  3. Ebp1 (show NFKB1 Proteins) has a role in the regulation of embryonic muscle progenitors and adult muscle stem cells, which likely operates independently of ErbB3 (show ERBB3 Proteins) signaling

  4. EBP1 (show NFKB1 Proteins) is in the cytoplasm & nucleolus. Nucleolar localization requires AA sequences at the NH2- and COOH-ends. Overexpression inhibits proliferation of human fibroblasts. It is part of RNP (show RNPC3 Proteins) complexes & associates with different rRNAs.

  5. These results strongly suggest that PA2G4 may have an important role on the regulation of DNA replication in eukaryotic cells.

  6. IGF-1 (show IGF1 Proteins) production and IGBP-3 and 4 protein levels were reduced in both embryo fibroblasts and adult knock-out mice. The proliferation of fibroblasts derived from Day 12.5 knock out embryos was also decreased as compared to that of wild type cells.

Human Proliferation-Associated 2G4, 38kDa (PA2G4) interaction partners

  1. The combined determination of Ebp1 (show NFKB1 Proteins) and p53 (show TP53 Proteins) expression levels in cervical cancer patients could support the effective prediction of metastatic potential and patient prognosis.

  2. Data highlight the tissue specificity function of EBP1 (show NFKB1 Proteins) isoforms and show that only the oncogene (show RAB1A Proteins) p48 (show IRF9 Proteins) activates MHC II expression in human solid tumors, via STAT1 (show STAT1 Proteins) phosphorylation, in order to affect tumor progression by triggering specific immune response.

  3. Our results suggest a novel function of Ebp1 (show NFKB1 Proteins) as a binding protein and negative regulator of Anxa2 (show ANXA2 Proteins). The functional association between Anxa2 (show ANXA2 Proteins) and EBP1 (show NFKB1 Proteins) may participate in regulating cancer cell proliferation and invasion, contributing to cancer progression.

  4. Ebp1 (show NFKB1 Proteins) functionality is independent from heat-shock-protein-regulated progression networks in prostate cancer.

  5. EBP1 (show NFKB1 Proteins) participates in the regulation of intestinal inflammation via mediating Akt (show AKT1 Proteins) signaling pathway.

  6. Data suggest that inhibiting ErbB3-binding protein 1 Ebp1 phosphorylation may be an effective mechanism for inhibiting T-cell activation and proliferation.

  7. Ebp1 (show NFKB1 Proteins) p42 (show EPB42 Proteins) isoform regulates the proteasomal degradation of the p85 regulatory subunit of PI3K (show PIK3CA Proteins) by recruiting a chaperone-E3 ligase complex HSP70 (show HSP70 Proteins)/CHIP.

  8. data suggest that Vpr may inhibit Ebp1 (show NFKB1 Proteins) to stabilize p53 (show TP53 Proteins), which in turn leads to G2 arrest and apoptosis in U87MG cells

  9. The major effect of EBP1 (show NFKB1 Proteins) on ErbB2 (show ERBB2 Proteins) mRNA expression levels is at the transcriptional level.

  10. Down-regulation of the ErbB3 binding protein 1 in human bladder cancer promotes tumor progression and cell proliferation.

Proliferation-Associated 2G4, 38kDa (PA2G4) Protein Profile

Protein Summary

This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified.

Gene names and symbols associated with PA2G4

  • proliferation-associated 2G4, 38kDa (PA2G4)
  • proliferation-associated 2G4, 38kDa (pa2g4)
  • similar to proliferation-associated 2G4, 38kD (Pa2g4)
  • proliferation-associated protein 2G4-like (PA2G4)
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (Nfkb1)
  • proliferation-associated 2G4 (Pa2g4)
  • proliferation-associated 2G4, a (pa2g4a)
  • 38kDa protein
  • AA672939 protein
  • DKFZp469G2132 protein
  • EBP-1 protein
  • EBP1 protein
  • HG4-1 protein
  • MGC81621 protein
  • NF-kB protein
  • p38-2G4 protein
  • Pa2g4 protein
  • pa2g4-a protein
  • Plfap protein
  • si:dz150i12.2 protein
  • wu:fb19b11 protein
  • wu:ft56d05 protein
  • zgc:86732 protein

Protein level used designations for PA2G4

proliferation-associated 2G4, 38kDa , ErbB3-binding protein 1 , proliferation-associated protein 2G4 , proliferation-associated protein 2G4-like , similar to proliferation-associated 2G4, 38kD , DNA-binding factor KBF1 , nuclear factor NF-kappa-B p105 subunit , nuclear factor of kappa light chain gene enhancer in B-cells 1, p105 , nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 , IRES-specific cellular trans-acting factor 45 kDa , ITAF45 , mpp1 , proliferation-associated 2G4, 38kD , proliferation-associated protein 1 , protein p38-2G4 , ErbB-3 binding protein 1 , ErbB3-binding protein Ebp1 , cell cycle protein p38-2G4 homolog , erbB3-binding protein 1

GENE ID SPECIES
467034 Pan troglodytes
493284 Xenopus (Silurana) tropicalis
711482 Macaca mulatta
100013526 Monodelphis domestica
100051912 Equus caballus
100171565 Pongo abelii
100410842 Callithrix jacchus
100468984 Ailuropoda melanoleuca
399238 Xenopus laevis
693641 Macaca mulatta
81736 Rattus norvegicus
18813 Mus musculus
288778 Rattus norvegicus
444257 Xenopus laevis
5036 Homo sapiens
474396 Canis lupus familiaris
540272 Bos taurus
100519773 Sus scrofa
368737 Danio rerio
425279 Gallus gallus
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