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PELP1 encodes a transcription factor which coactivates transcription of estrogen receptor responsive genes and corepresses genes activated by other hormone receptors or sequence-specific transcription factors. Additionally we are shipping PELP1 Proteins (3) and many more products for this protein.
Showing 10 out of 84 products:
Human Polyclonal PELP1 Primary Antibody for IHC (p), IP - ABIN152367
Migliaccio, Di Domenico, Castoria, Nanayakkara, Lombardi, de Falco, Bilancio, Varricchio, Ciociola, Auricchio: Steroid receptor regulation of epidermal growth factor signaling through Src in breast and prostate cancer cells: steroid antagonist action. in Cancer research 2005
Show all 18 Pubmed References
Human Polyclonal PELP1 Primary Antibody for IP - ABIN258234
Habashy, Rakha, Aleskandarany, Ahmed, Green, Ellis, Powe: FOXO3a nuclear localisation is associated with good prognosis in luminal-like breast cancer. in Breast cancer research and treatment 2011
Show all 2 Pubmed References
The data demonstrate that SUMO2 (show SUMO2 Antibodies) conjugation and SENP3 (show ULP1 Antibodies)-driven deSUMOylation of PELP1 is instrumental for ordered progression of ribosome maturation, and they provide molecular insight into the dynamics of ribosome maturation.
High PELP1 expression is associated with inflammation and breast cancer.
three techniques for the first time demonstrated the presence of the PELP1 in paraspinal muscles of patients with idiopathic scoliosis.
PELP1 interacted with GR to activate Brk (show PTK6 Antibodies) expression.
we propose that PELP1/Ki-67 (show MKI67 Antibodies) double high expression in tumors is an independent prognostic factor for predicting a poor outcome for patients with Triple-negative breast cancer
There is mounting evidence that PELP1 plays key roles in several biological processes and its deregulation leads to the development of cancers.
There are significantly higher amounts of PELP1 transcript and protein in tumor tissues in patients with non-small cell lung cancer.
The diffuse and strong nuclear immunoreactivity of PELP1 in most cases suggests that PELP1 may be a molecular target for the treatment of triple-negative breast carcinoma
Results show that PELP1 is highly phosphorylated in triple negative breast cancer cells and interacts with mutated Tp53 (show TP53 Antibodies) and E2F1 (show E2F1 Antibodies) to differentially regulates their target gene expression.
The PELP1 interacts with p53 (show TP53 Antibodies), functions as p53 (show TP53 Antibodies)-coactivator and is required for optimal activation of p53 (show TP53 Antibodies) target genes under genomic stress.
MNAR/PELP1 is expressed and colocalizes with glucocorticoid receptors in monkey and rat brains.
PELP1 is essential for the extranuclear signaling and neuroprotective actions of 17-beta estradiol in the hippocampal CA1 (show CA1 Antibodies) region after global cerebral ischemia.
These results further support the hypothesis that PELP1 deregulation has the potential to promote breast tumorigenesis in vivo and represent a novel model for future investigation into molecular mechanisms of PELP1-mediated tumorigenesis.
PELP1 recruits HDAC2 (show HDAC2 Antibodies) and masks histones using two separate domains
This gene encodes a transcription factor which coactivates transcription of estrogen receptor responsive genes and corepresses genes activated by other hormone receptors or sequence-specific transcription factors. Expression of this gene is regulated by both members of the estrogen receptor family. Alternative splicing results in multiple transcript variants.
proline, glutamate and leucine rich protein 1
, proline-, glutamic acid-, leucine-rich protein 1
, proline, glutamic acid and leucine rich protein 1
, proline, glutamic acid and leucine rich protein 1-like
, modulator of non-genomic activity of estrogen receptor
, proline and glutamic acid rich nuclear protein
, proline-, glutamic acid- and leucine-rich protein 1
, transcription factor HMX3
, modulator of nongenomic activity of estrogen receptor
, modulator of nongenomic actions of the estrogen receptor