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May be part of the TORC2 complex which plays a critical role in AKT1 'Ser-473' phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cytoskeleton organization (By similarity).. Additionally we are shipping PRR5L Proteins (4) and many more products for this protein.
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Human Polyclonal PRR5L Primary Antibody for EIA, WB - ABIN783444
Thedieck, Polak, Kim, Molle, Cohen, Jenö, Arrieumerlou, Hall: PRAS40 and PRR5-like protein are new mTOR interactors that regulate apoptosis. in PLoS ONE 2007
Protor-2 associates with tristetraprolin (TTP (show ZFP36 Antibodies)) to accelerate TTP (show ADAMTS13 Antibodies)-mediated mRNA turnover and functionally links the control of TTP (show ADAMTS13 Antibodies)-regulated mRNA stability to mTORC2 (show CRTC2 Antibodies) activity
It was demonstrated that immunoprecipitation of Protor-1 (show PRR5 Antibodies) or Protor-2 results in the co-immunoprecipitation of other mTORC2 (show CRTC2 Antibodies) subunits, but not Raptor (show RPTOR Antibodies), a specific component of mTORC1.
PRR5L degradation promotes mTORC2 (show CRTC2 Antibodies)-mediated PKC-delta (show PKCd Antibodies) phosphorylation and cell migration downstream of Galpha12 (show GNA12 Antibodies) in fibroblasts and pulmonary fibrosis.
May be part of the TORC2 complex which plays a critical role in AKT1 'Ser-473' phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cytoskeleton organization (By similarity).
proline rich 5 like
, proline-rich protein 5-like
, Protein observed with Rictor-2
, protein observed with Rictor-2