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Proline Rich Nuclear Receptor Coactivator 2 (PNRC2) ELISA Kits

Involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery. Additionally we are shipping PNRC2 Antibodies (13) and PNRC2 Proteins (9) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human PNRC2 PNRC2 55629 Q9NPJ4
Anti-Mouse PNRC2 PNRC2 52830 Q9CR73
Anti-Rat PNRC2 PNRC2 100125373 Q66HE1
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More ELISA Kits for PNRC2 Interaction Partners

Human Proline Rich Nuclear Receptor Coactivator 2 (PNRC2) interaction partners

  1. GR and PNRC2 interact in a ligand-dependent manner to recruit UPF1 (show UPF1 ELISA Kits) for rapid mRNA degradation

  2. PNRC2 acts in synergy with Dcp1a (show DCP1A ELISA Kits) to stimulate the decapping activity of Dcp2 (show DCP2 ELISA Kits) by bridging the interaction between Dcp1a (show DCP1A ELISA Kits) and Dcp2 (show DCP2 ELISA Kits).

  3. Not only PNRC2 but also the corepressor TLE1 functioned as ERRgamma (show ESRRG ELISA Kits) coactivator in a reporter gene analysis.

  4. PNRC2 plays an essential role in mammalian Nonsense-mediated mRNA decay (NMD), mediating the interaction between the NMD machinery and the decapping complex.

Mouse (Murine) Proline Rich Nuclear Receptor Coactivator 2 (PNRC2) interaction partners

  1. The finding that the PNRC2 promoter is activated by NFY and repressed by E2F1 (show E2F1 ELISA Kits) indicates that in addition to functioning as nuclear receptor coactivator, PNRC2 may also play a role in the cell cycle.

  2. Study provides evidence that PNRC2 plays one or more important roles in controlling the energy balance between energy storage and energy expenditure. PNRC2 may be a new target in the treatment of obesity and related metabolic diseases.

PNRC2 Antigen Profile

Antigen Summary

Involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery. May act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs. Required for upf1/rent1 localization to the P-body. Also acts as a nuclear receptor coactivator (By similarity).

Gene names and symbols associated with PNRC2

  • proline-rich nuclear receptor coactivator 2 (PNRC2) antibody
  • proline-rich nuclear receptor coactivator 2 (Pnrc2) antibody
  • proline-rich nuclear receptor coactivator 2 (pnrc2) antibody
  • 0610011E17Rik antibody
  • D4Bwg0593e antibody
  • wu:cegs2777 antibody
  • wu:fb51a04 antibody
  • wu:fb81a06 antibody
  • wu:fd19g06 antibody

Protein level used designations for PNRC2

fb81a06

GENE ID SPECIES
55629 Homo sapiens
52830 Mus musculus
100125373 Rattus norvegicus
767836 Bos taurus
419688 Gallus gallus
100195218 Salmo salar
565522 Danio rerio
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