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Prolyl 4-Hydroxylase, beta Polypeptide Proteins (P4HB)

Protein disulfide isomerases (EC 5.3.4.1), such as PDIP, are endoplasmic reticulum (ER) resident proteins that catalyze protein folding and thiol-disulfide interchange reactions (Desilva et al., 1996 [PubMed 8561901]).[supplied by OMIM, Mar 2008].. Additionally we are shipping PDI Antibodies (191) and PDI Kits (43) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
P4HB 18600 Q08642
P4HB 5034 P07237
P4HB 25506 P04785
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Top PDI Proteins at antibodies-online.com

Showing 10 out of 49 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 2 to 3 Days
$231.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 21 to 26 Days
$313.50
Details
Yeast Human His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag,GST tag 100 μg Log in to see 11 to 13 Days
$756.80
Details
HOST_Escherichia coli (E. coli) Human His tag,GST tag 100 μg Log in to see 11 to 13 Days
$756.80
Details
HOST_Escherichia coli (E. coli) Rat His tag,GST tag 100 μg Log in to see 11 to 13 Days
$838.20
Details
HOST_Escherichia coli (E. coli) Human GST tag Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) (AA 29-313), (partial) protein (GST tag) 1 mg Log in to see 56 to 66 Days
$1,317.80
Details

P4HB Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , , , ,
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Rat (Rattus) ,
,

Top referenced PDI Proteins

  1. Human PDI Protein expressed in Escherichia coli (E. coli) - ABIN667180 : Pihlajaniemi, Myllylä, Kivirikko: Prolyl 4-hydroxylase and its role in collagen synthesis. in Journal of hepatology 1992 (PubMed)
    Show all 2 references for ABIN667180

  2. Human PDI Protein expressed in Escherichia coli (E. coli) - ABIN413737 : Pendurthi, Ghosh, Mandal, Rao: Tissue factor activation: is disulfide bond switching a regulatory mechanism? in Blood 2007 (PubMed)
    Show all 2 references for ABIN413737

More Proteins for Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) Interaction Partners

Mouse (Murine) Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) interaction partners

  1. GPx7 (show GPX7 Proteins) is an unusual CysGPx catalyzing the peroxidatic cycle by a one Cys (show DNAJC5 Proteins) mechanism in which GSH and PDI (show PDIA3 Proteins) are alternative substrates.

  2. Neutrophil surface PDI is important for alphaMbeta2 integrin-mediated adhesion of human neutrophils under shear and static conditions and for binding of soluble fibrinogen to activated alphaMbeta2 integrin.

  3. Unfolded protein response caused by protein misfolding, may lead to PDI-dependent NOX activation and contribute to neurotoxicity in neurodegenerative diseases including ALS.

  4. Results suggest that PADI2 (show PADI2 Proteins) may function as an important new biomarker for HER2/ERBB2 (show ERBB2 Proteins)+ tumors and that Cl-amidine represents a new candidate for breast cancer therapy.

  5. Activation of the P2X7 purinergic receptor (P2X7 (show P2RX7 Proteins)) by the inflammatory danger signal ATP induces PAD2 activity and robust protein citrullination in mast cells.

  6. These results indicate that both endothelial and platelet beta3 integrins contribute to extracellular PDI (show PDIA3 Proteins) binding at the vascular injury site.

  7. different subcellular compartmentalization of PADi2 (show PADI2 Proteins) and citrullinated proteins may have different physiological roles in normal and neurodegenerative conditions

  8. PDI (show PDIA3 Proteins) from endothelial cells is required for fibrin generation in vivo.

  9. PAD2 interacts with IKKgamma (show IKBKG Proteins) and suppresses NF-kappaB (show NFKB1 Proteins) activity.

  10. Protein disulfide isomerase (PDI) on the platelet surface is recognized by anti-dengue virus NS1 (show IVNS1ABP Proteins) antibodies.

Human Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) interaction partners

  1. the effect of the endoplasmic reticulum chaperone protein disulfide isomerase (PDI) on beta-cell dysfunction, was examined.

  2. Amyotrophic lateral sclerosis-linked PDIA1 mutations disrupt motor neuron connectivity.

  3. direct binding of PDIA1 to VWF (show VWF Proteins), is reported.

  4. Tissue factor (show F3 Proteins)-regulated vascular smooth cell migration and microvessel formation is under the control of the ER-protein PDIA2 (show PDIA2 Proteins).

  5. It was found that PDI interacts with dengue virus nonstructural protein 1 (NS1) intracellularly as well as on the surface in the lipid raft domain.

  6. Selective sequestration of PDI1A in a calcium depletion-mediated complex with the abundant chaperone calreticulin (show CALR Proteins) attenuates the effective concentration of this major lumenal thiol oxidant.

  7. Data show that cell surface disulfide isomerase (PDI) expression and function regulate the capacity of natriuretic peptides to generate cyclic guanosine monophosphate (cGMP) through interaction with their receptors.

  8. Cole-Carpenter syndrome is caused by a specific de novo mutation in P4HB that impairs the disulfide isomerase activity of protein disulfide isomerase.

  9. PDI (show PADI1 Proteins) has a role as a competent regulator and a specific substrate of Ero1alpha govern efficient and faithful oxidative protein folding and maintain the ER redox homeostasis

  10. These results indicate that BPA (show DST Proteins), a widely distributed and potentially harmful chemical, inhibits Ero1-PDI (show PADI1 Proteins)-mediated disulfide bond formation.

Cow (Bovine) Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) interaction partners

  1. Rotavirus-protein disulfide isomerase interaction was demonstrated in vitro as well as inMA104 cells and intestinal villi from suckling mice.

PDI (P4HB) Protein Profile

Protein Summary

Protein disulfide isomerases (EC 5.3.4.1), such as PDIP, are endoplasmic reticulum (ER) resident proteins that catalyze protein folding and thiol-disulfide interchange reactions (Desilva et al., 1996

Gene names and symbols associated with P4HB

  • Protein disulfide isomerase (Pdi)
  • prolyl 4-hydroxylase, beta polypeptide (P4HB)
  • peptidyl arginine deiminase, type II (Padi2)
  • prolyl 4-hydroxylase, beta polypeptide (P4hb)
  • prolyl 4-hydroxylase, beta polypeptide (p4hb)
  • protein disulfide isomerase family A, member 2 (PDIA2)
  • protein disulfide isomerase family A, member 2 (pdia2)
  • CG6988 protein
  • Dmel\\CG6988 protein
  • dpdi protein
  • DSI protein
  • EP(3)1022 protein
  • ERBA2L protein
  • ERp59 protein
  • GIT protein
  • mKIAA0994 protein
  • P4Hbeta protein
  • p55 protein
  • PDA2 protein
  • Pdi protein
  • Pdi2 protein
  • Pdia1 protein
  • PDIP protein
  • PDIR protein
  • PHDB protein
  • PO4DB protein
  • PO4HB protein
  • PROHB protein
  • Thbp protein
  • XPDIp protein

Protein level used designations for P4HB

CG6988-PA , CG6988-PD , Pdi-PA , Pdi-PD , disulfide isomerase , proline diisomerease , protein disulfide isomerase , protein disulphide isomerase , protein-disulfide isomerase , procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide , prolyl 4-hydroxylase, beta subunit , protein disulfide-isomerase , PAD type II , peptidyl arginine deiminase, type II; PAD type II , peptidylarginine deiminase II , protein-arginine deiminase type II , protein-arginine deiminase type-2 , cellular thyroid hormone-binding protein , collagen prolyl 4-hydroxylase beta , glutathione-insulin transhydrogenase , p55 , prolyl 4-hydroxylase subunit beta , protein disulfide isomerase family A, member 1 , protein disulfide isomerase-associated 1 , protein disulfide isomerase/oxidoreductase , protocollagen hydroxylase , thyroid hormone-binding protein p55 , ER protein 59 , endoplasmic reticulum resident protein 59 , Protein disulfide isomerase (Prolyl 4-hydroxylase, beta polypeptide) , R-cognin , procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase-associated 1) , procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase; thyroid hormone binding protein p55) , retina cognin , PDI (E.C.5.3.4.1) , cellular thyroid hormone binding protein , prolyl 4-hydroxylase beta polypeptide , Cellular thyroid hormone-binding protein , Prolyl 4-hydroxylase subunit beta , multifunctional thyroid hormone binding protein , PDI , Rho GDP dissociation inhibitor gamma , pancreas-specific protein disulfide isomerase , pancreatic protein disulfide isomerase , protein disulfide isomerase A2 , protein disulfide isomerase, pancreatic , protein disulfide isomerase-associated 2 , protein disulfide-isomerase A2

GENE ID SPECIES
39651 Drosophila melanogaster
454970 Pan troglodytes
18600 Mus musculus
5034 Homo sapiens
18453 Mus musculus
25506 Rattus norvegicus
399248 Xenopus laevis
374091 Gallus gallus
281373 Bos taurus
100328595 Oryctolagus cuniculus
483369 Canis lupus familiaris
100733944 Cavia porcellus
100173809 Pongo abelii
64714 Homo sapiens
399040 Xenopus laevis
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