Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) ELISA Kits

PCSK9 encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. Additionally we are shipping PCSK9 Antibodies (160) and PCSK9 Proteins (64) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
PCSK9 255738 Q8NBP7
PCSK9 100102 Q80W65
PCSK9 298296 P59996
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Top PCSK9 ELISA Kits at antibodies-online.com

Showing 10 out of 77 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.11 ng/mL 0.45-30 ng/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details
Mouse 10pg/mL 62.5-4000 pg/mL Mouse PCSK9 PicoKine ELISA Kit standard curve 96 Tests Log in to see 4 to 6 Days
$399.00
Details
Monkey 1.1 pg/mL 1.1-800 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$1,026.67
Details
Rat 1.25 ng/mL 3.125-200 ng/mL 96 Tests Log in to see 15 to 17 Days
$973.11
Details
Human 0.12 ng/mL 0.312-20 ng/mL   96 Tests Log in to see 2 to 3 Days
$581.90
Details
Mouse 6.4 pg/mL 15.62 pg/mL - 1000 pg/mL   96 Tests Log in to see 8 to 12 Days
$787.25
Details
Rat 1.19 ng/mL 3.12 ng/mL - 200 ng/mL   96 Tests Log in to see 8 to 12 Days
$829.25
Details
Pig 0.469 ng/mL 0.781-50 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Rabbit 0.188 ng/mL 0.313-20 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Chicken 4.688 ng/mL 7.813-500 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details

Top referenced PCSK9 ELISA Kits

  1. Human PCSK9 ELISA Kit for Sandwich ELISA - ABIN2345049 : Jin, Park, Kim, Vaziri: Plasma PCSK9 in nephrotic syndrome and in peritoneal dialysis: a cross-sectional study. in American journal of kidney diseases : the official journal of the National Kidney Foundation 2014 (PubMed)
    Show all 3 Pubmed References

  2. Mouse (Murine) PCSK9 ELISA Kit for Sandwich ELISA - ABIN2685159 : Seidah, Benjannet, Wickham, Marcinkiewicz, Jasmin, Stifani, Basak, Prat, Chretien: The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation. in Proceedings of the National Academy of Sciences of the United States of America 2003 (PubMed)
    Show all 3 Pubmed References

  3. Human PCSK9 ELISA Kit for Sandwich ELISA - ABIN820112 : Dogan, Akman, Simsek, Ozdem, Comak, Gokceoglu, Kardelen, Koyun: Assessment of left ventricular function by tissue Doppler echocardiography in pediatric chronic kidney disease. in Renal failure 2015 (PubMed)
    Show all 2 Pubmed References

More ELISA Kits for PCSK9 Interaction Partners

Human Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) interaction partners

  1. Rare variants of APOB (show APOB ELISA Kits) or PCSK9 were identified in nine of the 22 study patients with extremely low LDL-C levels

  2. PCSK9 plays a direct role on Abca1 (show ABCA1 ELISA Kits)-mediated cholesterol efflux through a downregulation of Abca1 (show ABCA1 ELISA Kits) gene and Abca1 (show ABCA1 ELISA Kits) protein expression. This extrahepatic effect may influence relevant steps in the pathogenesis of atherosclerosis, such as foam cell formation.

  3. kidney function per se does not impact significantly PCSK9 metabolism

  4. Sirolimus therapy in heart transplant patients is associated with elevation in PCSK9 levels which is not associated with sirolimus-induced hypercholesterolemia.

  5. PCSK9 inhibits lipoprotein(a) clearance through the LDLR (show LDLR ELISA Kits).

  6. PCSK9 variants reduced fasting LDL-C as well as fasting triglycerides.

  7. Proprotein convertase subtilisin/kexin 9 V4I variant with LDLR (show LDLR ELISA Kits) mutations modifies the phenotype of familial hypercholesterolemia

  8. PCSK9 associated with Familial Hypercholesterolemia and Polygenic Hypercholesterolemia in patients with Acute Coronary Syndrome , age /=160 mg/dl.

  9. Results clearly that PCSK9 serum concentrations were associated to liver function and mortality, pointed to the disturbance of steroid regulation in patients with end-stage liver disease and an association of such disturbance with mortality. Further studies are required to acquire a more detailed understanding of the role of PCSK9 in liver-related mortality.

  10. Use Crispr-Cas (show CSE1L ELISA Kits) system to introduce nonsense variants into PCSK9 to lower blood cholesterol levels.

Mouse (Murine) Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) interaction partners

  1. PCSK9 inhibits lipoprotein(a) clearance through the LDLR (show LDLR ELISA Kits).

  2. Use Crispr-Cas (show CTNND1 ELISA Kits) system to introduce nonsense variants into PCSK9 to lower blood cholesterol levels.

  3. Studied the combination model of a single AAV-PCSK9 injection, high-fat diet, and partial carotid ligation which induces robust atherosclerosis in the flow-disturbed carotid artery within 3 weeks in C57 mice, and results suggest this is a quick and convenient model to study atherosclerosis and mechanisms using any knockout or transgenic mice without having to generate double knockouts.

  4. These observations suggest positive feedback interplay between SMC (show DYM ELISA Kits)-derived PCSK9 and mtDNA damage in the proinflammatory milieu involving mtROS. This interaction results in cellular injury, characterized by apoptosis-a hallmark of atherosclerosis.

  5. AdipoR activation by agonists regulated PCSK9 expression and inhibits atherosclerosis in apoE (show APOE ELISA Kits)(-/-) mice.

  6. Adeno (show ADORA2A ELISA Kits)-associated virus mediated infection with a mouse PCSK9 gain-of-function mutation is a rapid, easy, and efficient approach for inducing hypercholesterolemia and promoting abdominal aortic aneurysms in C57BL/6 mice infused with angiotensin II.

  7. conditions that cause ER stress regardless of their ability to dysregulate ER Ca(2 (show CA2 ELISA Kits)+) inhibit PCSK9 secretion, thereby reducing PCSK9-mediated LDLR (show LDLR ELISA Kits) degradation and promoting LDLR (show LDLR ELISA Kits)-dependent hepatic cholesterol uptake.

  8. Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Single Domain Antibodies Are Potent Inhibitors of Low Density Lipoprotein Receptor (show LDLR ELISA Kits) Degradation.

  9. PCSK9 increases hepatic lipid and lipoprotein production via apoE (show APOE ELISA Kits)- and LDLR (show LDLR ELISA Kits)-dependent mechanisms

  10. Podocyte damage triggers marked inductions in plasma PCSK9, and knockout of Pcsk9 ameliorates dyslipidemia in a mouse model of nephrotic syndrome.

PCSK9 Antigen Profile

Antigen Summary

This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3).

Gene names and symbols associated with PCSK9

  • proprotein convertase subtilisin/kexin type 9 L homeolog (pcsk9.L) antibody
  • proprotein convertase subtilisin/kexin type 9 (pcsk9) antibody
  • proprotein convertase subtilisin/kexin type 9 (PCSK9) antibody
  • proprotein convertase subtilisin/kexin type 9 (Pcsk9) antibody
  • AI415265 antibody
  • AI747682 antibody
  • FH3 antibody
  • HCHOLA3 antibody
  • LDLCQ1 antibody
  • NARC-1 antibody
  • Narc1 antibody
  • PC9 antibody

Protein level used designations for PCSK9

proprotein convertase subtilisin/kexin type 9 , convertase subtilisin/kexin type 9 preproprotein , neural apoptosis regulated convertase 1 , subtilisin/kexin-like protease PC9 , NARC-1 , convertase subtilisin , neural apoptosis-regulated convertase 1 , proprotein convertase 9 , proprotein convertase PC9 , proprotein convertase subtilisin/kexin type 9 preproprotein , Proprotein convertase 9 , Subtilisin/kexin-like protease PC9

GENE ID SPECIES
495509 Xenopus laevis
100150316 Danio rerio
100544916 Meleagris gallopavo
255738 Homo sapiens
100102 Mus musculus
298296 Rattus norvegicus
424664 Gallus gallus
100731533 Cavia porcellus
717147 Macaca mulatta
100971792 Pan paniscus
456880 Pan troglodytes
100395116 Callithrix jacchus
100620501 Sus scrofa
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