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Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) ELISA Kits

PCSK9 encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. Additionally we are shipping PCSK9 Antibodies (152) and PCSK9 Proteins (61) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
PCSK9 255738 Q8NBP7
PCSK9 100102 Q80W65
PCSK9 298296 P59996
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Top PCSK9 ELISA Kits at antibodies-online.com

Showing 10 out of 72 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.11 ng/mL 0.45-30 ng/mL Typical standard curve 96 Tests Log in to see 11 to 13 Days
$910.56
Details
Mouse 10pg/mL 62.5-4000 pg/mL Mouse PCSK9 PicoKine ELISA Kit standard curve 96 Tests Log in to see 4 to 6 Days
$399.00
Details
Monkey 1.1 pg/mL 1.1-800 pg/mL Typical standard curve 96 Tests Log in to see 11 to 13 Days
$1,026.67
Details
Rat 1.19 ng/mL 3.12-200 ng/mL 96 Tests Log in to see 13 to 16 Days
$640.00
Details
Chicken 4.688 ng/mL 7.813-500 ng/mL   96 Tests Log in to see 8 to 9 Days
$715.00
Details
Guinea Pig 0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 8 to 9 Days
$715.00
Details
Pig 0.469 ng/mL 0.781-50 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Rabbit 0.188 ng/mL 0.313-20 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Mouse 94-6000 pg/mL   1 kit Log in to see 9 Days
$891.43
Details
Dog
  96 Tests Log in to see 11 to 13 Days
$707.14
Details

Top referenced PCSK9 ELISA Kits

  1. Mouse (Murine) PCSK9 ELISA Kit for Sandwich ELISA - ABIN2685159 : Seidah, Benjannet, Wickham, Marcinkiewicz, Jasmin, Stifani, Basak, Prat, Chretien: The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation. in Proceedings of the National Academy of Sciences of the United States of America 2003 (PubMed)
    Show all 3 references for ABIN2685159

  2. Human PCSK9 ELISA Kit for Sandwich ELISA - ABIN820112 : Dogan, Akman, Simsek, Ozdem, Comak, Gokceoglu, Kardelen, Koyun: Assessment of left ventricular function by tissue Doppler echocardiography in pediatric chronic kidney disease. in Renal failure 2015 (PubMed)
    Show all 2 references for ABIN820112

More ELISA Kits for PCSK9 Interaction Partners

Human Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) interaction partners

  1. the zymogen form of PCSK9 adopts a structure that is distinct from the processed form and is unable to bind a mimetic peptide based on the EGF (show EGF ELISA Kits)-A domain of the LDLr (show LDLR ELISA Kits).

  2. CRP (show CRP ELISA Kits) increased PCSK9 expression by activating p38MAPK (show MAPK14 ELISA Kits)-HNF1alpha (show HNF1A ELISA Kits) pathway, with a certain downstream impairment in LDL metabolism in HepG2 cells.

  3. PCSK9 C-terminal domain (CTD) was found to be essential to induce LDLR (show LDLR ELISA Kits) degradation both upon its overexpression in cells or via the extracellular pathway.

  4. Results show that circulating PCSK9 concentration increases with the severity of hepatic fat accumulation in patients at risk of nonalcoholic fatty liver disease.

  5. PCSK9 inhibition with alirocumab on top of statin treatment has the potential to lower LDL cholesterol in some autosomal recessive hypercholesterolemia patients.

  6. CRISPR-Cas9 therapy targeting the human PCSK9 gene in chimeric liver-humanized mice bearing human hepatocytes.

  7. PCSK9 regulates monocyte CCR2 expression and chemotaxis.

  8. PCSK9 is down-regulated in patients with rheumatoid arthritis.

  9. Carriers of the PCSK9 R46L genetic variant have lower very low-density lipoprotein and low-density lipoprotein particle concentrations, lower lipoprotein(a) levels, and lower secretory phospholipase A2 (show YWHAZ ELISA Kits) and lipoprotein-associated phospholipase A2 activity, reducing cardiovascular risk.

  10. PCSK9 R46L carriers have lower levels of lipoprotein(a) and LDL cholesterol and is associated with reduced risk of aortic valve stenosis and myocardial infarction.

Mouse (Murine) Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) interaction partners

  1. AdipoR activation by agonists regulated PCSK9 expression and inhibits atherosclerosis in apoE (show APOE ELISA Kits)(-/-) mice.

  2. Adeno (show ADORA2A ELISA Kits)-associated virus mediated infection with a mouse PCSK9 gain-of-function mutation is a rapid, easy, and efficient approach for inducing hypercholesterolemia and promoting abdominal aortic aneurysms in C57BL/6 mice infused with angiotensin II.

  3. conditions that cause ER stress regardless of their ability to dysregulate ER Ca(2 (show CA2 ELISA Kits)+) inhibit PCSK9 secretion, thereby reducing PCSK9-mediated LDLR (show LDLR ELISA Kits) degradation and promoting LDLR (show LDLR ELISA Kits)-dependent hepatic cholesterol uptake.

  4. Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Single Domain Antibodies Are Potent Inhibitors of Low Density Lipoprotein Receptor (show LDLR ELISA Kits) Degradation.

  5. PCSK9 increases hepatic lipid and lipoprotein production via apoE (show APOE ELISA Kits)- and LDLR (show LDLR ELISA Kits)-dependent mechanisms

  6. Podocyte damage triggers marked inductions in plasma PCSK9, and knockout of Pcsk9 ameliorates dyslipidemia in a mouse model of nephrotic syndrome.

  7. polydatin ameliorates lipid and glucose metabolism in type 2 diabetes mellitus by downregulating PCSK9.

  8. binding of PCSK9 to GRP94 (show HSP90B1 ELISA Kits) protects LDLR (show LDLR ELISA Kits) from degradation likely by preventing early binding of PCSK9 to LDLR (show LDLR ELISA Kits)

  9. The absence of PCSK9 results in a sex- and tissue-specific subcellular distribution of the LDLR (show LDLR ELISA Kits) and VLDLR (show VLDLR ELISA Kits), which is determined by estradiol levels.

  10. that ox-LDL receptor-1 (show OLR1 ELISA Kits) and PCSK9 positively influence each other's expression, especially during an inflammatory reaction

PCSK9 Antigen Profile

Antigen Summary

This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3).

Gene names and symbols associated with PCSK9

  • proprotein convertase subtilisin/kexin type 9 (pcsk9) antibody
  • proprotein convertase subtilisin/kexin type 9 (PCSK9) antibody
  • proprotein convertase subtilisin/kexin type 9 (Pcsk9) antibody
  • proprotein convertase subtilisin/kexin type 9-like (LOC100620501) antibody
  • AI415265 antibody
  • AI747682 antibody
  • FH3 antibody
  • HCHOLA3 antibody
  • LDLCQ1 antibody
  • NARC-1 antibody
  • Narc1 antibody
  • PC9 antibody

Protein level used designations for PCSK9

proprotein convertase subtilisin/kexin type 9 , convertase subtilisin/kexin type 9 preproprotein , neural apoptosis regulated convertase 1 , subtilisin/kexin-like protease PC9 , NARC-1 , convertase subtilisin , neural apoptosis-regulated convertase 1 , proprotein convertase 9 , proprotein convertase PC9 , proprotein convertase subtilisin/kexin type 9 preproprotein , Proprotein convertase 9 , Subtilisin/kexin-like protease PC9

GENE ID SPECIES
495509 Xenopus laevis
100150316 Danio rerio
100544916 Meleagris gallopavo
255738 Homo sapiens
100102 Mus musculus
298296 Rattus norvegicus
424664 Gallus gallus
100731533 Cavia porcellus
717147 Macaca mulatta
100971792 Pan paniscus
456880 Pan troglodytes
100395116 Callithrix jacchus
100620501 Sus scrofa
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