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anti-Prospero Homeobox 1 (PROX1) Antibodies

The protein encoded by PROX1 is a member of the homeobox transcription factor family. Additionally we are shipping Prospero Homeobox 1 Proteins (4) and Prospero Homeobox 1 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PROX1 5629 Q92786
PROX1 305066  
PROX1 19130 P48437
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Top anti-Prospero Homeobox 1 Antibodies at antibodies-online.com

Showing 10 out of 146 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Immunofluorescence on a frozen section of a mouse embryo at day 13.5 with anti-CD31 [green] and anti-human Prox-1 [red] (#ABIN115694). It shows a large lymphatic vessel (lv), blood vessels (arrows) and a sympathetic ganglion (sg) which is also positiv for Prox-1 (courtesy of PD. Dr. J. Wilting) 0.2 mg Log in to see 6 to 8 Days
$412.50
Details
Human Rabbit Un-conjugated EIA, IHC (fro), IF, IHC (p), WB Immunofluorescence on a frozen section of a mouse embryo at day 13.5 with anti-CD31 [green] and anti-human Prox-1 [red] (#DP3516). It shows a large lymphatic vessel (lv), blood vessels (arrows) and a sympathetic ganglion (sg) which is also positiv for Prox-1 (courtesy of PD. Dr. J. Wilting) 50 μg Log in to see 6 to 8 Days
$308.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts from A431 cells using Prospero homeobox protein 1and the same antibody preincubated with blocking peptide. 0.1 mL Log in to see 6 to 8 Days
$308.00
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (fro), IHC (p), WB Detectionof human Prox1 inMz-ChA-2gall bladder carcinoma cells. Proteins were isolated by differential proteome extraction according to the procedure described in (1) or by SDS extraction. Lysates were separated through a standard SDS-polyacrylamide gel and transferred to a PVDF-membrane. Primary antibody was incubated in a 1:1000 dilution with the membrane for 12 h followed by a secondary anti-rabbit peroxidase-coupled antibody in a 1:9000 dilution for1 h. Washed filters were subjected to enhanced chemiluminescence (ECL) and exposed to an X-ray film for 30 min. (1) Abdolzade-Bavil A, Hayes S, Goretzki L, Krueger M, Anders J, Hendriks R (2004) Convenient and versatile subcellular extraction procedure, that facilitates classical protein expression profiling and functional protein analysis. Proteomics 4:1397–1405 0.2 mL Log in to see 6 to 8 Days
$412.50
Details
Human Rabbit Un-conjugated WB PROX-1 Antibody (S197) (ABIN1881686) western blot analysis in SH-SY5Y cell line lysates (35 µg/lane). This demonstrates the PROX-1 antibody detected the PROX-1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Chicken Mouse Un-conjugated IHC (fro), IHC (p) 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Rabbit Un-conjugated IHC (fro), IF, WB Immunofluorescence on a frozen section of a mouse embryo at day 13.5 with anti-CD31 [green] and anti-human Prox-1 [red] (#DP3516). It shows a large lymphatic vessel (lv), blood vessels (arrows) and a sympathetic ganglion (sg) which is also positiv for Prox-1 (courtesy of PD. Dr. J. Wilting) 0.1 mg Log in to see 6 to 8 Days
$308.00
Details

PROX1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Prospero Homeobox 1 Antibodies

  1. Human Polyclonal PROX1 Primary Antibody for EIA, IHC (p) - ABIN357418 : Nagai, Li, Hatano, Toshihito, Yuge, Ito, Utsumi, Saito, Kinoshita: Mutations and aberrant DNA methylation of the PROX1 gene in hematologic malignancies. in Genes, chromosomes & cancer 2003 (PubMed)
    Show all 6 references for ABIN357418

  2. Human Polyclonal PROX1 Primary Antibody for EIA, IHC (p) - ABIN357417 : Dyer, Livesey, Cepko, Oliver: Prox1 function controls progenitor cell proliferation and horizontal cell genesis in the mammalian retina. in Nature genetics 2003 (PubMed)
    Show all 6 references for ABIN357417

  3. Human Polyclonal PROX1 Primary Antibody for EIA, WB - ABIN357416 : Hong, Harvey, Noh, Schacht, Hirakawa, Detmar, Oliver: Prox1 is a master control gene in the program specifying lymphatic endothelial cell fate. in Developmental dynamics : an official publication of the American Association of Anatomists 2002 (PubMed)
    Show all 5 references for ABIN357416

  4. Human Polyclonal PROX1 Primary Antibody for IHC (fro), IF - ABIN115696 : Glasgow, Tomarev: Restricted expression of the homeobox gene prox 1 in developing zebrafish. in Mechanisms of development 1998 (PubMed)
    Show all 5 references for ABIN115696

  5. Human Polyclonal PROX1 Primary Antibody for EIA, IHC (fro) - ABIN115695 : Krishnan, Kirkin, Steffen, Hegen, Weih, Tomarev, Wilting, Sleeman: Differential in vivo and in vitro expression of vascular endothelial growth factor (VEGF)-C and VEGF-D in tumors and its relationship to lymphatic metastasis in immunocompetent rats. in Cancer research 2003 (PubMed)
    Show all 5 references for ABIN115695

  6. Human Polyclonal PROX1 Primary Antibody for IF, IHC (p) - ABIN115694 : Padera, Kadambi, di Tomaso, Carreira, Brown, Boucher, Choi, Mathisen, Wain, Mark, Munn, Jain: Lymphatic metastasis in the absence of functional intratumor lymphatics. in Science (New York, N.Y.) 2002 (PubMed)
    Show all 5 references for ABIN115694

  7. Human Polyclonal PROX1 Primary Antibody for WB - ABIN1881686 : Petrova, Mäkinen, Mäkelä, Saarela, Virtanen, Ferrell, Finegold, Kerjaschki, Ylä-Herttuala, Alitalo: Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor. in The EMBO journal 2002 (PubMed)
    Show all 4 references for ABIN1881686

  8. Human Polyclonal PROX1 Primary Antibody for WB - ABIN616059 : Charest-Marcotte, Dufour, Wilson, Tremblay, Eichner, Arlow, Mootha, Giguère: The homeobox protein Prox1 is a negative modulator of ERR{alpha}/PGC-1{alpha} bioenergetic functions. in Genes & development 2010 (PubMed)
    Show all 3 references for ABIN616059

  9. Human Polyclonal PROX1 Primary Antibody for IHC (fro), IHC (p) - ABIN115665 : Webster, Miller, Dusold, Ramos-Vara: Effects of prolonged formalin fixation on diagnostic immunohistochemistry in domestic animals. in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2009 (PubMed)
    Show all 2 references for ABIN115665

  10. Chicken Monoclonal PROX1 Primary Antibody for IHC (fro), IHC (p) - ABIN371836 : Chen, Patel, Cain, Duncan: Production of monoclonal antibodies against Prox1. in Hybridoma (2005) 2006 (PubMed)
    Show all 2 references for ABIN371836

More Antibodies against Prospero Homeobox 1 Interaction Partners

Human Prospero Homeobox 1 (PROX1) interaction partners

  1. High PROX1 expression is associated with Esophageal Squamous Cell Carcinoma.

  2. Reduced expression of Prox1 is beneficial for the expansion and maturation of beta-cells.

  3. PROX1 is an important regulator of endocrine secretory granule formation in medullary thyroid cancer cells.

  4. Findings demonstrate that NOTCH (show NOTCH1 Antibodies)-induced PROX1 inactivation significantly promotes the malignant behavior of thyroid carcinoma.

  5. These results suggest that the hepatic functions of the human iPS (show SLC27A4 Antibodies)-HLCs (show HLCS Antibodies) could be enhanced by ATF5 (show ATF5 Antibodies), c/EBPalpha (show CEBPA Antibodies), and PROX1 transduction.

  6. In primary lymphatic endothelial cells (HDLEC), miR (show MLXIP Antibodies)-466 mimic transfection suppressed Prox1 mRNA and protein expression. HDLEC transfected with the miR (show MLXIP Antibodies)-466 mimic suppressed tube formation as compared to the scrambled control.

  7. Increase in PROX1 expression renders HCC (show FAM126A Antibodies) cells more resistant to sorafenib treatment.

  8. Our results indicate that immunohistochemical detection of PROX1 correlates with a more malignant phenotype in rectal neuroendocrine tumors

  9. PROX1 target genes and show that repression of a pro-apoptotic member of the BCL2 (show BCL2 Antibodies) family, BCL2L15, is important for survival of PROX1(+) cells under metabolic stress.

  10. Prox1 regulates PDPN (show PDPN Antibodies) expression at the transcriptional level in the lymphatic vascular system

Mouse (Murine) Prospero Homeobox 1 (PROX1) interaction partners

  1. the data show that Prox1 (show C16orf35 Antibodies) regulates proliferation and differentiation of the oligodendrocyte cell lineage, and is a relevant component of the endogenous regenerative response to Central nervous system injury.

  2. Prox1 (show C16orf35 Antibodies) upregulation reduces proliferation, impairs maturation, and enables apoptosis in postnatal beta-cells. Prox1 (show C16orf35 Antibodies) overexpression causes MafA (show MAFA Antibodies) deficiency in beta-cells.

  3. The PROX1 (show C16orf35 Antibodies)-mediated repression is weakened or lost, thereby facilitating the induction of Reverse cholesterol transport genes and diminishing the progression of atherosclerosis

  4. suggest that Prox1 (show C16orf35 Antibodies) appears to be a critical stage specific regulator of specifying ascending thin limb cell fate and that its expression is regulated by osmolality

  5. we demonstrate that Prox1 (show C16orf35 Antibodies) and Asap1 (show ASAP1 Antibodies) behave as negative regulators of mammary stem/progenitor function. Both of these genes have also been implicated in oncogenesis.

  6. Prox1 (show C16orf35 Antibodies) is made in postmitotic CGE-derived cortical interneuron precursors. It is differentially required during embryonic and postnatal stages for migration, differentiation, circuit integration, and maintenance programs in subtypes of these interneurons.

  7. Sox2 (show SOX2 Antibodies) was not restricted to developing taste bud cells expressing Prox1 (show C16orf35 Antibodies) during circumvallate development.

  8. Expression of fluorescent Prox-1 allows functional characterization of Schlemm's canal.

  9. Prox1 (show C16orf35 Antibodies) is essential for the expansion of the stem cell pool in intestinal adenomas and CRC (show SCRIB Antibodies) without being critical for the normal functions of the gut (show GUSB Antibodies).

  10. Prox1 (show C16orf35 Antibodies) expression was observed in all parts of the endolymphatic sac (show ADCY10 Antibodies) epithelia.

Zebrafish Prospero Homeobox 1 (PROX1) interaction partners

  1. using a transgenic reporter line, we show that prox1a is initially expressed in different endothelial compartments, becoming restricted to lymphatic endothelial cells only at later stages

  2. Functional analysis using antisense morpholinos indicates that prox1 activity is crucial for the hair cells to differentiate properly and acquire functionality, while having no role in development of other cell types in neuromasts.

  3. Prox1 functions as a tissue-specific coregulator of Ff1b

  4. Our findings indicate that prox1 activity is crucial for the proper development of the otp1 (show OTOP1 Antibodies)-positive hypothalamic neuronal precursors to their terminal CA phenotype

Prospero Homeobox 1 (PROX1) Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the homeobox transcription factor family. Members of this family contain a homeobox domain that consists of a 60-amino acid helix-turn-helix structure that binds DNA and RNA. The protein encoded by this gene is conserved across vertebrates and may play an essential role during development. Altered levels of this protein have been reported in cancers of different organs, such as colon, brain, blood, breast, pancreas, liver and esophagus. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with PROX1

  • prospero homeobox 1 (PROX1) antibody
  • prospero homeobox 1 (prox1) antibody
  • prospero-related homeobox 1 (LOC100232600) antibody
  • prospero homeobox 1 (Prox1) antibody
  • prospero-related homeobox 1 (Prox1) antibody
  • prospero-related homeobox gene 1a (prox1a) antibody
  • A230003G05Rik antibody
  • LOC100232600 antibody
  • prospero antibody
  • prox1 antibody
  • xprox1 antibody
  • zgc:111888 antibody

Protein level used designations for PROX1

prospero homeobox 1 , prospero homeobox protein 1-like , Prox 1 , prospero-related homeobox 1 , homeobox prospero-like protein PROX1 , prospero homeobox protein 1 , PROX-1 , prospero-related homeobox gene 1

GENE ID SPECIES
100050316 Equus caballus
100357251 Oryctolagus cuniculus
100404369 Callithrix jacchus
100440139 Pongo abelii
100466739 Ailuropoda melanoleuca
100603654 Nomascus leucogenys
399348 Xenopus laevis
457728 Pan troglodytes
100134995 Xenopus (Silurana) tropicalis
100232600 Taeniopygia guttata
100567246 Anolis carolinensis
5629 Homo sapiens
305066 Rattus norvegicus
395802 Gallus gallus
490291 Canis lupus familiaris
100169702 Sus scrofa
515324 Bos taurus
19130 Mus musculus
30679 Danio rerio
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