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anti-Prostacyclin Receptor (PTGIR) Antibodies

The protein encoded by PTGIR is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Additionally we are shipping Prostacyclin Receptor Proteins (5) and Prostacyclin Receptor Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PTGIR 19222 P43252
PTGIR 5739 P43119
PTGIR 292661 P43253
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Top anti-Prostacyclin Receptor Antibodies at antibodies-online.com

Showing 10 out of 64 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from K562 cells, using Prostacyclin ... Immunofluorescence analysis of LOVO cells, using Prostacyclin Receptor... 100 μg Log in to see 2 to 3 Days
$275.00
Details
Human Rabbit Un-conjugated IHC (p), WB PTGIR Antibody (Center) (ABIN658348) western blot analysis in K562 cel... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated WB Western Blot analysis of PTGIR expression in transfected 293T cell lin... 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IHC (p) Anti-Prostaglandin I2 Receptor antibody  ABIN1049252 IHC staining of h... 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p) Immunohistochemical staining of prostacyclin receptor on human platele... 50 μg Log in to see 6 to 8 Days
$500.50
Details
Mouse Rabbit Un-conjugated WB   200 μg Log in to see 8 to 10 Days
$683.83
Details
Mouse Rabbit Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$405.17
Details
Human Rabbit Un-conjugated IF, ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details

PTGIR Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine) , , ,

Human , , , ,
,
Rat (Rattus) ,

Top referenced anti-Prostacyclin Receptor Antibodies

  1. Human Polyclonal Prostacyclin Receptor Primary Antibody for WB - ABIN2801905 : Boie, Rushmore, Darmon-Goodwin, Grygorczyk, Slipetz, Metters, Abramovitz: Cloning and expression of a cDNA for the human prostanoid IP receptor. in The Journal of biological chemistry 1994 (PubMed)
    Show all 4 references for ABIN2801905

  2. Human Polyclonal Prostacyclin Receptor Primary Antibody for IF, ELISA - ABIN1535983 : Nakagawa, Tanaka, Usui, Harada, Sasaki, Itoh, Yoshimasa, Namba, Narumiya, Nakao: Molecular cloning of human prostacyclin receptor cDNA and its gene expression in the cardiovascular system. in Circulation 1994 (PubMed)

More Antibodies against Prostacyclin Receptor Interaction Partners

Mouse (Murine) Prostacyclin Receptor (PTGIR) interaction partners

  1. Prostacyclin promotes the up-regulation of Nox4 (show NOX4 Antibodies) in endothelial cells, which opens up a novel strategy that protects and enhances endothelial cell functions in cardiovascular disease, such as repair after myocardial infarction or other ischemic conditions.

  2. Its signaling increase cAMP concentration, which prototes sysnesis of HGF (show HGF Antibodies), causing angiogenesis.

  3. an essential role of the COX-2 (show COX2 Antibodies)/PGI2 receptor axis in the cardioprotection afforded by the late ischemic preconditioning

  4. findings suggest the IP receptor might maintain an angiogenic switch in the "on" state in tumor endothelial cells (TEC); suggest that the IP receptor is a TEC-specific marker and might be a useful therapeutic target

  5. PGI2-induced PPAR delta (show PPARD Antibodies) activation accelerates blastocyst hatching in mice

  6. For the first time these results show that activation of prostaglandin I2 receptor can attenuate damage following cerebral ischemia.

  7. identify PGI(2)-prostaglandin I2 receptor as an important pathway for inhibiting allergic pulmonary inflammation by controlling recruitment of CD4 (show CD4 Antibodies)(+) Th2 cells into the inflammatory site

  8. The prostacyclin/IP pathway suppresses cardiac fibrosis, at least partly, by inducing CREB (show CREB1 Antibodies) phosphorylation.

  9. Prostaglandin I2 receptor signaling promotes T helper cell type (Th)1 (show TH1L Antibodies) differentiation through a cyclic adenosine monophosphate (AMP (show TMPRSS5 Antibodies))-protein kinase A pathway, thereby initiating acquired cutaneous immune responses.

  10. critical differences in signaling by the mIP and hIP that are regulated by their differential phosphorylation by PKA and PKC

Human Prostacyclin Receptor (PTGIR) interaction partners

  1. these findings suggest that reduced IPR expression in DM2 (show CNBP Antibodies) platelets may contribute to platelet hyperactivity in humans with type 2 diabetes.

  2. Prostaglandin I2- Prostaglandin I2 receptor signaling regulates human Th17 and Treg cell differentiation.

  3. these data provide critical insights into the transcriptional regulation of the human prostacyclin receptor gene within the vasculature, including during megakaryocytic differentiation

  4. IP receptor heteridimerization with thromboxane receptor (show TBXA2R Antibodies) facilitates receptor trafficking to membrane lipid rafts.

  5. Prostacyclin receptor-dependent inhibition of human erythroleukemia cell differentiation is STAT3 (show STAT3 Antibodies)-dependent

  6. IKEPP (show PDZD3 Antibodies) was also found to be expressed in vascular endothelial cells where it co-localizes and complexes with the hIP

  7. the IP receptor was expressed in blood vessels of renal cell carcinoma specimens, but not in glomerular vessels of normal renal tissue; findings suggest the IP receptor might maintain an angiogenic switch in the "on" state in tumor endothelial cells (TEC); suggest that the IP receptor is a TEC-specific marker and might be a useful therapeutic target

  8. VDAC is the ATP conduit in the IP receptor-mediated signaling pathway in human erythrocytes.

  9. Human prostacyclin receptor interacts with the PDZ (show INADL Antibodies) adapter protein (show TOLLIP Antibodies) PDZK1 (show PDZK1 Antibodies); this interaction plays important role in endothelial cell migration and angiogenesis.

  10. IP(R212C) exerts a dominant action on the wild-type IP and thromboxane receptor (show TBXA2R Antibodies) through dimerization. This likely contributes to accelerated cardiovascular disease in individuals carrying 1 copy of the variant allele.

Prostacyclin Receptor (PTGIR) Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor.

Gene names and symbols associated with PTGIR

  • prostaglandin I receptor (IP) (Ptgir) antibody
  • prostaglandin I2 (prostacyclin) receptor (IP) (PTGIR) antibody
  • prostaglandin I2 (prostacyclin) receptor (IP) (Ptgir) antibody
  • IP antibody
  • PGI2 antibody
  • PRIPR antibody

Protein level used designations for PTGIR

PGI receptor , PGI2 receptor , prostacyclin receptor , prostaglandin I2 receptor , prostanoid IP receptor , prostaglandin I receptor (IP)

GENE ID SPECIES
19222 Mus musculus
5739 Homo sapiens
292661 Rattus norvegicus
520278 Bos taurus
Selected quality suppliers for anti-Prostacyclin Receptor (PTGIR) Antibodies
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