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Prostaglandin D2 Receptor (DP) Proteins (PTGDR)

The protein encoded by PTGDR is a G-protein-coupled receptor. Additionally we are shipping Prostaglandin D2 Receptor (DP) Antibodies (43) and Prostaglandin D2 Receptor (DP) Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PTGDR 19214 P70263
Rat PTGDR PTGDR 63889 O35932
PTGDR 5729 Q13258
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Top Prostaglandin D2 Receptor (DP) Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Wheat germ Human Un-conjugated   2 μg Log in to see 9 Days
$491.43
Details

PTGDR Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Prostaglandin D2 Receptor (DP) (PTGDR) Interaction Partners

Mouse (Murine) Prostaglandin D2 Receptor (DP) (PTGDR) interaction partners

  1. A role for PGD2 (show PTGDS Proteins) signals acting through PTGDR in suppression of intestinal tumors.

  2. Data indicate a PLA2G3 (show PLA2G3 Proteins)-lipocalin (show APOD Proteins)-type PGD2 synthase (L-PGDS)-PGD2 (show PTGDS Proteins) receptor DP1 loop that drives mast cell maturation.

  3. PGD(2)-DP signaling reduces vascular permeability both in vivo.

  4. platelet DP1 (show REEP5 Proteins) is not present in mice. Despite this, DP1 (show REEP5 Proteins) deletion in mice augmented aneurysm formation and the hypertensive response to Ang II (show AGT Proteins) and accelerated atherogenesis and thrombogenesis.

  5. The present study demonstrates that functional roles of PGD2 and its receptors appear to depend on the nature of the inflammation in chronic skin inflammation, chronic contact hypersensitivity and IgE-mediated chronic allergic skin inflammation

  6. After epicutaneous sensitization with ovalbumin (show OVA Proteins) (OVA), DP activation inhibits the migration of Langerhans cells (LC)s and affects the priming of antigen-specific T cells in the draining lymph nodes.

  7. pain sensitivity was increased in prostaglandin D receptor mutant mice

Human Prostaglandin D2 Receptor (DP) (PTGDR) interaction partners

  1. PGD2 (show PTGDS Proteins) markedly augments disease activity through its ability to enhance the proinflammatory actions of macrophages and subsequent neutrophil activation.

  2. Non-obligatory role of prostaglandin D2 receptor subtype 1 in rosacea: laropiprant in comparison to a placebo did not alleviate the symptoms of erythematoelangiectaic rosacea

  3. EP2 (show SPAG11B Proteins) receptors exhibit more constraints to mutations than DP receptors.

  4. Low DP1 prostanoid receptor is associated with gastric cancer progression.

  5. Lipocalin (show APOD Proteins)-type prostaglandin D2 (PGD2) synthase (L-PGDS) interacts intracellularly with the G protein-coupled receptor (show ADRA1A Proteins) DP1 in an agonist-independent manner.

  6. the PTGDR -549 C/T polymorphism confers susceptibility to asthma in Europeans and adults. However, no association was found between the PTGDR 441 C/T and -197 C/T polymorphisms or the CCC and TCT (show TRPM7 Proteins) haplotypes and asthma susceptibility.

  7. PGD(2)-DP signaling reduces vascular permeability via endothelial cAMP/PKA/Tiam1/Rac1 pathway.

  8. The PTGDR -441C/T polymorphism is not associated with asthma or its phenotypes in the North Indian population.

  9. DP receptors amplify the biological response to CRTH2 activation and the CRTH2/DP heteromer might represent both a functional signaling unit for PGD(2) and a potential target for development of heteromer-directed therapy for allergic diseases

  10. Genetic combinations described have functional implications in the PTGDR promoter activity by changing the transcription factors affinity that will help characterize different risk groups.

Prostaglandin D2 Receptor (DP) (PTGDR) Protein Profile

Protein Summary

The protein encoded by this gene is a G-protein-coupled receptor. It has been shown to function as a prostanoid DP receptor. The activity of this receptor is mainly mediated by G-S proteins that stimulate adenylate cyclase resulting in an elevation of intracellular cAMP and Ca2+. Knockout studies in mice suggest that the ligand of this receptor, prostaglandin D2 (PGD2), functions as a mast cell-derived mediator to trigger asthmatic responses.

Gene names and symbols associated with PTGDR

  • prostaglandin D2 receptor (DP) (PTGDR)
  • prostaglandin D2 receptor (PTGDR)
  • prostaglandin D receptor (Ptgdr)
  • prostaglandin D2 receptor (Ptgdrl)
  • prostaglandin D2 receptor-like (Ptgdr)
  • AS1 protein
  • ASRT1 protein
  • DP protein
  • DP1 protein
  • PGD protein
  • Ptgdr protein
  • PTGDR1 protein
  • Ptgdr2 protein
  • RGD1565108 protein

Protein level used designations for PTGDR

prostaglandin D2 receptor (DP) , prostaglandin D2 receptor , PGD receptor , PGD2 receptor , prostanoid DP receptor , prostaglandin D receptor , prostaglandin D2 receptor-like , Prostanoid DP receptor

GENE ID SPECIES
452906 Pan troglodytes
610845 Canis lupus familiaris
707918 Macaca mulatta
100582498 Nomascus leucogenys
19214 Mus musculus
63889 Rattus norvegicus
5729 Homo sapiens
515331 Bos taurus
498475 Rattus norvegicus
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