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anti-Prostaglandin E Receptor 1 (Subtype EP1), 42kDa (PTGER1) Antibodies

The protein encoded by PTGER1 is a member of the G protein-coupled receptor family. Additionally we are shipping Prostaglandin E Receptor 1 (Subtype EP1), 42kDa Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PTGER1 19216 P35375
PTGER1 25637 P70597
PTGER1 5731 P34995
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Top anti-Prostaglandin E Receptor 1 (Subtype EP1), 42kDa Antibodies at antibodies-online.com

Showing 10 out of 58 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated EIA, IHC (p) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated IHC (p) Kidney, Renal tubules 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat kidney labeled with Anti PTGE... Lane 1: mouse kidney lysates probed with Anti PTGER1 Polyclonal Antibo... 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC (p) Anti-PTGER1 / EP1 antibody  ABIN1049253 IHC staining of human kidney, ... 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Goat Un-conjugated ELISA, IHC (p) Human Spleen (formalin-fixed, paraffin-embedded) stained with PTGER1 a... 50 μg Log in to see 8 to 10 Days
$451.00
Details
Mouse Rabbit Un-conjugated ELISA, WB   50 μL Log in to see 8 to 10 Days
$566.50
Details
Human Rabbit Un-conjugated WB   100 μg Log in to see 8 to 10 Days
$463.83
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

PTGER1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine) , , , ,

Rat (Rattus) , , , ,

Human , , , ,
,

Top referenced anti-Prostaglandin E Receptor 1 (Subtype EP1), 42kDa Antibodies

  1. Human Polyclonal PTGER1 Primary Antibody for ELISA, WB - ABIN185589 : Han, Wu: Cyclooxygenase-2-derived prostaglandin E2 promotes human cholangiocarcinoma cell growth and invasion through EP1 receptor-mediated activation of the epidermal growth factor receptor and Akt. in The Journal of biological chemistry 2005 (PubMed)

More Antibodies against Prostaglandin E Receptor 1 (Subtype EP1), 42kDa Interaction Partners

Mouse (Murine) Prostaglandin E Receptor 1 (Subtype EP1), 42kDa (PTGER1) interaction partners

  1. EP1-/- mice maintain increased bone mineral density and stronger cortical and trabecular bone biomechanical properties with aging. The EP1 receptor acts to inhibit bone marrow osteoprogenitor cell differentiation and mineralization.

  2. Results indicate that EP1 receptor activation during seizures, through a protein kinase C (show PKC Antibodies) pathway, increases probability of kainic acid induced status epilepticus, and independently promotes hippocampal neurodegeneration and a broad inflammatory response

  3. The EP1 receptor facilitates the actions of angiotensin II, thereby suggesting that targeting of both the renin (show REN Antibodies)-angiotensin system and the EP1 receptor could be beneficial in diabetic nephropathy.

  4. Propose a mechanism whereby ANG II (show AGT Antibodies) increases COX-1 (show PTGS1 Antibodies)-derived PGE2 through the AT1R (show AGTRAP Antibodies)/PLA2 (show PLA2G2A Antibodies) pathway, which promotes ROS (show ROS1 Antibodies) production by EP1R/Nox2 (show CYBB Antibodies) signaling in the subfornical organ.

  5. dietary administration and direct injection of the EP1 receptor-specific antagonist, ONO-8713, effectively reduced the growth of established CT26 (show DDX53 Antibodies) tumors in BALB/c mice

  6. EP1 deletion protects mice from asymmetrical Parkinsonism. The PGE2 EP1 receptor is implicated in 6-OHDA-induced Parkinsonism.

  7. Data suggest that EP1 receptor blockade may be a viable target for antihypertensive therapy.

  8. data suggest that the tumor promoting/progressing effects of EP1 require the PGE2 synthesized by COX-2 (show COX2 Antibodies)

  9. Peripheral EP1 receptors contribute significantly to inflammation induced heat pain sensitization while evidence for a contribution to central sensitization was not obtained.

  10. Upregulation of the EP1 receptor for prostaglandin E2 promotes skin tumor progression.

Human Prostaglandin E Receptor 1 (Subtype EP1), 42kDa (PTGER1) interaction partners

  1. A transient interaction between COX-2 (show COX2 Antibodies) and EP1 constitutes a feedback loop whereby an increase in COX-2 (show COX2 Antibodies) expression elevates EP1.

  2. NF-kappaB (show NFKB1 Antibodies) inhibitor suppressed 17-PT-PGE2-mediated FoxC2 (show FOXC2 Antibodies) upregulation. Immunohistochemistry showed p65 (show GORASP1 Antibodies), FoxC2 (show FOXC2 Antibodies), EP1 receptor and beta1-integrin were all highly expressed in the HCC (show FAM126A Antibodies) cases

  3. COX-1 (show COX1 Antibodies), H446K' is significantly more sensitive to downregulation by EP . Together these data suggest that distinctive ubiquitination of COX-1 (show COX1 Antibodies) and COX-2 (show COX2 Antibodies) may be responsible for their different sensitivity to EP -mediated degradation.

  4. through complex formation with D1, EP1 signaling directs the D1 receptor through G(betagamma) to be coupled to AC7 (show Adcy7 Antibodies).

  5. PGE2-enhanced MMP2 (show MMP2 Antibodies) expression is mediated through EP1 receptors and calcium signaling pathway-induced CREB (show CREB1 Antibodies) phosphorylation in human cholangiocarcinoma cells.

  6. Our study suggests that the PGE (show LIPF Antibodies) EP1 receptor regulates FAK (show PTK2 Antibodies) phosphorylation by activating the PKC (show PRRT2 Antibodies)/c-Src (show SRC Antibodies) and EGFR (show EGFR Antibodies) signal pathways, which may coordinately regulate adhesion and migration in HCC (show FAM126A Antibodies)

  7. PGE (show LIPF Antibodies)(2) -mediated NF-kappaB (show NFKB1 Antibodies) activation by simultaneous stimulation of EP(1) and EP(4 (show PTGER4 Antibodies)) receptors induces maximal IL-8 (show IL8 Antibodies) promoter activation and IL-8 (show IL8 Antibodies) mRNA and protein induction

  8. Suggest that the anti-carcinogenic effects of EGCG in hepatocellular carcinoma might be mediated, at least partially, through the suppressing EP(1) receptor expression and PGE (show LIPF Antibodies)(2) production.

  9. new role for the EP(1) receptor in resolving inflammation through down-regulation of COX-2 (show COX2 Antibodies).

  10. Neuroblastoma (show ARHGEF16 Antibodies) express all four forms of PGE (show LIPF Antibodies)(2) receptors.

Prostaglandin E Receptor 1 (Subtype EP1), 42kDa (PTGER1) Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). Through a phosphatidylinositol-calcium second messenger system, G-Q proteins mediate this receptor's activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin.

Gene names and symbols associated with PTGER1

  • prostaglandin E receptor 1 (subtype EP1), 42kDa (PTGER1) antibody
  • prostaglandin E receptor 1 (subtype EP1) (Ptger1) antibody
  • prostaglandin E2 receptor EP1 subtype-like (LOC100855637) antibody
  • 42kDa antibody
  • EP1 antibody
  • PTGER1 antibody
  • Ptgerep1 antibody

Protein level used designations for PTGER1

prostaglandin E receptor 1 (subtype EP1), 42kDa , prostaglandin E2 receptor subtype EP1 , PGE receptor EP1 subtype , PGE2 receptor EP1 subtype , prostaglandin E2 receptor EP1 subtype , prostanoid EP1 receptor , EP1 prostanoid receptor , PGE receptor, EP1 subtype , prostaglandin E receptor EP1 subtype , prostaglandin E receptor 1, subtype EP1

GENE ID SPECIES
747643 Pan troglodytes
100008680 Oryctolagus cuniculus
19216 Mus musculus
25637 Rattus norvegicus
5731 Homo sapiens
610774 Canis lupus familiaris
100855637 Canis lupus familiaris
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