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Prostaglandin E Receptor 2 (Subtype EP2), 53kDa Proteins (PTGER2)

PTGER2 encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Additionally we are shipping PTGER2 Antibodies (90) and PTGER2 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PTGER2 19217 Q62053
Rat PTGER2 PTGER2 81752 Q62928
PTGER2 5732 P43116
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Top PTGER2 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Wheat germ Human Un-conjugated   2 μg Log in to see 9 Days
$491.43
Details

PTGER2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Prostaglandin E Receptor 2 (Subtype EP2), 53kDa (PTGER2) Interaction Partners

Mouse (Murine) Prostaglandin E Receptor 2 (Subtype EP2), 53kDa (PTGER2) interaction partners

  1. EP2 (show SPAG11A Proteins) deficiency in MCs (show SMCP Proteins) augmented TGF-beta1 (show TGFB1 Proteins)-induced fibronectin (FN (show FN1 Proteins)), cyclooxygenase-2 (COX2 (show PTGS2 Proteins)), and CyclinD1 expression. Silencing of EP2 (show SPAG11A Proteins) also strengthened TGF-beta1 (show TGFB1 Proteins)-induced extracellular-signal-regulated kinase 1/2 (show MAPK3 Proteins) (ERK1/2) phosphorylation

  2. autocrine prostaglandin E2 signaling through EP receptors is essential for optimal CD4 (show CD4 Proteins)(+) T-cell activation.

  3. the blockade of EP2 (show SPAG11A Proteins) and EP4 (show PTGER4 Proteins) promotes mouse survival after cryptococcus infection by promoting the production of cytokines via TLR4 (show TLR4 Proteins), as well as the enhanced M1 polarization of alveolar macrophages

  4. COX-2-derived PGE2 inhibits IL-10 expression in brain microglia through a novel EP2- and beta-arrestin-dependent signaling pathway.

  5. Cardiac inflammation is reduced in EP-2 (show SPAG11A Proteins)-/- mice.

  6. Study suggests a deleterious role for the PGE2-EP2 (show SPAG11A Proteins) signaling axis in modulating brain injury, inflammation, and functional recovery following intracerebral hemorrhage

  7. The main finding of this study is that PGE2 EP2 (show SPAG11A Proteins)-/- neurons are more susceptible to hemin neurotoxicity than WT neurons and that activation of the EP2 receptor protected neurons from hemin neurotoxicity.

  8. it should be clarified as to which EP and/or FP receptor (show PTGFR Proteins) signals are physiologically essential for myometrial contraction and successful parturition.

  9. regulation of CD36 (show CD36 Proteins)-mediated Abeta (show APP Proteins) phagocytosis by suppression of EP2 (show SPAG11A Proteins) signaling may provide a new approach to suppressing some aspects of Alzheimer disease pathogenesis

  10. Data indicate that the prostaglandin E2 receptor EP2 (show SPAG11A Proteins)-silencing RNA strongly enhanced MCs (show SMCP Proteins) (mesangial cells) proliferation.

Human Prostaglandin E Receptor 2 (Subtype EP2), 53kDa (PTGER2) interaction partners

  1. that the expression of ERG (show ERG Proteins) in prostate cancer is linked to the expression of IL-6 (show IL6 Proteins) mediated by the prostanoid receptor EP2 (show SPAG11B Proteins)

  2. mPGES-1 (show PTGES Proteins) is downregulated via EGR1 (show EGR1 Proteins) and has a role in caffeine inhibition on PGE2 synthesis of HBx hepatocytes

  3. Altered expression of EP2 (show SPAG11B Proteins) in patients with aspirin-exacerbated respiratory disease contributes to deficient induction of IL-1RI, reducing the capacity of IL-1beta (show IL1B Proteins) to increase COX-2 and mPGES-1 (show PTGES Proteins) expression, which results in low PGE2 production

  4. Reduced EP2 receptor expression results in resistance to the antiproliferative effects of EP2 (show SPAG11B Proteins) signaling in nasal polyp fibroblasts from subjects with AERD and support a role for EP2 (show SPAG11B Proteins) signaling in the aberrant growth of nasal polyp tissue.

  5. Intracellular EP2 (show SPAG11B Proteins) prostanoid receptor promotes cancer-related phenotypes in PC3 (show PCSK1 Proteins) prostate cancer cells.

  6. In adjusted models, gestations were 3.3 days longer (95%CI 0.6, 6.0) for each interquartile range of PTGER2 DNA methylation (show HELLS Proteins).

  7. data show a protective role for the PGE2 receptors EP(2 (show SPAG11B Proteins)) and EP(4 (show PTGER4 Proteins)) following osmotic changes, through the reduction of human mast cell activity caused by calcium influx impairment and MAP kinase (show MAPK1 Proteins) inhibition.

  8. EP2 (show SPAG11B Proteins) receptors exhibit more constraints to mutations than DP receptors.

  9. Overall, our results demonstrate that p53 (show TP53 Proteins) is a negative regulator of aromatase (show CYP19A1 Proteins) in the breast and its inhibition by PGE2 provides a novel mechanism for aromatase (show CYP19A1 Proteins) regulation in obesity and breast cancer.

  10. PGE2 markedly enhanced Huh-7 cell invasion and migration ability by upregulating the expression level of Snail protein (show SNAI1 Proteins), and EP2 receptor played an important role in this process.

Cow (Bovine) Prostaglandin E Receptor 2 (Subtype EP2), 53kDa (PTGER2) interaction partners

  1. Data suggest that lysophosphatidic acid (LPA (show PLG Proteins)) up-regulates expression of SLCO2A1 (show SLCO2A1 Proteins) (prostaglandin [PG] transporter), PTGER2/PTGER4 (show PTGER4 Proteins) (PG receptors EP2 (show SPAG11A Proteins)/EP4 (show PTGER4 Proteins)), and mPGES1 (show PTGES Proteins)/cPGES (show PTGES3 Proteins) (microsomal/cytosolic PG E synthases) in luteal cells.

  2. Data suggest that estradiol up-regulates mRNA and protein expression of 3 prostanoid receptors in oviduct smooth muscle: EP2/PTGER2 (prostaglandin E receptor 2); EP4/PTGER4 (show PTGER4 Proteins) (prostaglandin E receptor 4); and FP/PTGFR (prostaglandin F2alpha receptor (show PTGFR Proteins)).

  3. EP2 (show SPAG11A Proteins) is the major cAMP-generating PGE (show LIPF Proteins)(2) receptor expressed and regulated in the bovine uterus during the estrous cycle and early pregnancy.

  4. COX-2 (show PTGS2 Proteins) and FP receptor (show PTGFR Proteins) contribute via changes in amount and distribution to mechanisms associated with parturition.

  5. Quantitative RT-PCR revealed significant higher expression of EP2 (show SPAG11A Proteins) and EP4 (show PTGER4 Proteins) in the pre-ovulatory phase compared with the luteal phase in the bovine oviduct

PTGER2 Protein Profile

Protein Summary

This gene encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma.

Gene names and symbols associated with PTGER2

  • prostaglandin E receptor 2a (subtype EP2) (ptger2a)
  • prostaglandin E receptor 2 (subtype EP2), 53kDa (ptger2)
  • prostaglandin E receptor 2 (subtype EP2), 53kDa (PTGER2)
  • prostaglandin E receptor 2 (subtype EP2) (Ptger2)
  • EP2 protein
  • MGC69060 protein
  • Ptger-ep2 protein
  • PTGER2 protein
  • ptger2l protein
  • Ptgerep2 protein
  • zgc:63974 protein

Protein level used designations for PTGER2

ep2 , prostaglandin E receptor 2 (subtype EP2), 53kDa , prostaglandin E2 receptor EP2 subtype , EP2 receptor , PGE receptor EP2 subtype , PGE2 receptor EP2 subtype , prostaglandin E receptor 2 (EP2 subtype) , prostaglandin E receptor EP2 subtype , prostaglandin E receptor subtype EP2 , prostanoid EP2 receptor , PGE receptor, EP2 subtype , prostaglandin E2 receptor type 2 , prostaglandin E2 receptor subtype EP2

GENE ID SPECIES
393608 Danio rerio
403391 Xenopus laevis
467459 Pan troglodytes
100034745 Gallus gallus
19217 Mus musculus
81752 Rattus norvegicus
5732 Homo sapiens
282329 Bos taurus
403797 Canis lupus familiaris
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