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Prostaglandin E Receptor 3 (Subtype EP3) Proteins (PTGER3)

The protein encoded by PTGER3 is a member of the G-protein coupled receptor family. Additionally we are shipping Prostaglandin E Receptor 3 (Subtype EP3) Antibodies (106) and Prostaglandin E Receptor 3 (Subtype EP3) Kits (15) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PTGER3 5733 P43115
Rat PTGER3 PTGER3 24929 P34980
PTGER3 19218  
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Top Prostaglandin E Receptor 3 (Subtype EP3) Proteins at antibodies-online.com

Showing 6 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag,GST tag 100 μg Log in to see 11 to 13 Days
$788.70
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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HOST_Wheat germ Human Un-conjugated   2 μg Log in to see 9 Days
$491.43
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details

PTGER3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3) Interaction Partners

Human Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3) interaction partners

  1. The present study identified the functions of EP3 and the mechanisms by which PGE2 regulates beta-catenin (show CTNNB1 Proteins) expression and promoted cholangiocarcinoma cell growth and invasion

  2. Our results show that oxLDL suppresses EP3 expression by activation of PPAR-g (show ARF6 Proteins) and subsequent inhibition of NF-kappaB (show NFKB1 Proteins) in macrophages.

  3. results demonstrate that risk of unsuccessful periodontal treatment is associated with tag SNPs in specific genes that regulate the inflammatory response, one of which is also associated with sPTB.

  4. Failure of cervical ripening, after local application of prostaglandins for labor induction, may be caused by the increased expression of EP3 and concomitant decrease in EP4 (show PTGER4 Proteins) expression.

  5. Human prostate cancer is associated with EP4 (show PTGER4 Proteins) and EP2 (show SPAG11B Proteins) overexpression and reduced EP3 expression.

  6. EP3 downregulation contributed to prostate carcinogenesis and to progression from androgen-dependent prostate cancer to castration-resistant prostate cancer by regulating androgen receptor (show AR Proteins) expression.

  7. Neuronal prostaglandin E2 receptor subtype EP3 mediates antinociception during inflammation.

  8. Prostaglandin E2 receptor, EP3, is induced in diabetic islets and negatively regulates glucose- and hormone-stimulated insulin (show INS Proteins) secretion.

  9. EP(3) receptors located postsynaptically strongly contract human pulmonary arteries.

  10. This study identify the PGE (show LIPF Proteins)(2) EP3 receptor as a novel proinflammatory, proamyloidogenic, and synaptotoxic signaling pathway, and suggest a role for COX (show COX8A Proteins)-PGE (show LIPF Proteins)(2) -EP3 signaling in the development of AD.

Rabbit Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3) interaction partners

  1. For the mutant receptors, the second extracellular loop (ECII) plays a critical role in linking the agonist bound receptor conformation to the G protein nucleotide bound state.

Mouse (Murine) Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3) interaction partners

  1. Leukotriene D4 and prostaglandin E2 signals synergize and potentiate vascular inflammation in a mast cell-dependent manner through cysteinyl leukotriene receptor 1 (show CYSLTR1 Proteins) and E-prostanoid receptor 3

  2. Data (including data from studies in knockout mice) suggest that Ptger3 is involved in regulation of adiposity, lipid metabolism, and insulin (show INS Proteins) resistance; Ptger3 knockout mice gain more weight on high-fat diet than normal mice.

  3. EP3 activation facilitates hypoxia-induced vascular remodeling and pulmonary hypertension in mice.

  4. EP3 and TLR3 (show TLR3 Proteins) in conjunctival epithelium play a critical role in regulating ocular surface inflammation.

  5. PGE2 triggers mast cell activation via an EP3-Gi/o-Ca(2 (show CA2 Proteins)+) influx/PI3K pathway. This mechanism underlies PGE2-induced vascular permeability and consequent edema formation.

  6. Neointimal hyperplasia response to injury is mediated through prostaglndin EP3 receptor.

  7. Prostaglandin E2 receptor, EP3, is induced in diabetic islets and negatively regulates glucose- and hormone-stimulated insulin (show INS Proteins) secretion.

  8. These results suggest that EP3 receptors are involved in stroke injury through the enhancement of inflammatory and apoptotic reactions in the ischemic cortex.

  9. Suggest that COX-2 and EP3/EP4 (show PTGER4 Proteins) signaling contribute to lymphangiogenesis in proliferative inflammation, possibly via induction of VEGF-C (show VEGFC Proteins) and VEGF-D (show Figf Proteins).

  10. EP3 receptor signaling on endothelial cells is essential for the MMP-9 (show MMP9 Proteins) upregulation that enhances tumor metastasis and angiogenesis.

Pig (Porcine) Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3) interaction partners

  1. vasoconstriction is mediated by phosphatidyl-inositol pathway via activation of EP1 (show PTGER1 Proteins)- and EP3-receptors located on the smooth muscle cells

Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PTGER3

  • prostaglandin E receptor 3 (subtype EP3) (PTGER3)
  • similar to Prostaglandin E2 receptor, EP3 subtype (Prostanoid EP3 receptor) (PGE receptor, EP3 subtype) (PGE2-R) (PTGER3)
  • prostaglandin E receptor 3 (subtype EP3) (ptger3)
  • prostaglandin E receptor 3 (subtype EP3) (Ptger3)
  • EP3 protein
  • EP3-I protein
  • EP3-II protein
  • EP3-III protein
  • EP3-IV protein
  • EP3e protein
  • PGE2-R protein
  • Pgerep3 protein
  • PTGER3 protein
  • Ptgerep3 protein
  • Rep3 protein
  • rEP3a protein
  • rEP3b protein

Protein level used designations for PTGER3

prostaglandin E2 receptor EP3 subtype , prostaglandin E receptor 3, subtype EP3 , prostaglandin E receptor 3 (subtype EP3) , PGE receptor, EP3 subtype , PGE2 receptor EP3 subtype , prostaglandin E receotor EP3 subtype 3 isoform , prostaglandin receptor (PGE-2) , prostanoid EP3 receptor , PGE receptor EP3 subtype , prostaglandin EP3 receptor subtype , prostaglandin E receptor EP3 subtype , prostaglandin E2 receptor EP3B subtype , Prostaglandin E2 receptor EP3 subtype

GENE ID SPECIES
429116 Gallus gallus
456940 Pan troglodytes
703398 Macaca mulatta
100049776 Xenopus laevis
100053557 Equus caballus
100593534 Nomascus leucogenys
5733 Homo sapiens
100009389 Oryctolagus cuniculus
282330 Bos taurus
24929 Rattus norvegicus
19218 Mus musculus
403430 Canis lupus familiaris
396811 Sus scrofa
443496 Ovis aries
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