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PTGR2 encodes an enzyme involved in the metabolism of prostaglandins. Additionally we are shipping PTGR2 Antibodies (55) and many more products for this protein.
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Human PTGR2 Protein expressed in Escherichia coli (E. coli) - ABIN1098255
Wu, Ko, Guo, Hu, Chuang, Wang: Structural basis for catalytic and inhibitory mechanisms of human prostaglandin reductase PTGR2. in Structure (London, England : 1993) 2008
Show all 2 references for ABIN1098255
Silencing of PTGR2 expression enhances reactive oxygen species production, suppresses pancreatic cell proliferation, and promotes cell death through increasing 15-keto-PGE2.
Functional data and clinical relevance for the role of PTGR2 in gastric cancer, are provided.
Besides targeting cyclooxygenase, indomethacin inhibits PTGR2 with a binding mode similar to that of 15-keto-PGE (show LIPF Proteins)(2).
This mouse gene encodes a putative NADPH-dependent oxidoreductase. We report the crystal structure of the putative oxidoreductase determined by the semi-automated high-throughput pipeline of the Joint Center for Structural Genomics
15-oxoprostaglandin-Delta13-reductase (PGR-2) catalyzes the reaction converting 15-keto-PGE2 to 13,14-dihydro-15-keto-PGE2
This gene encodes an enzyme involved in the metabolism of prostaglandins. The encoded protein catalyzes the NADPH-dependent conversion of 15-keto-prostaglandin E2 to 15-keto-13,14-dihydro-prostaglandin E2. This protein may also be involved in regulating activation of the peroxisome proliferator-activated receptor. Alternative splicing results in multiple transcript variants.
zinc binding alcohol dehydrogenase, domain containing 1
, prostaglandin reductase 2
, Zinc-binding alcohol dehydrogenase domain-containing protein 1
, 15-oxoprostaglandin 13-reductase
, zinc-binding alcohol dehydrogenase domain-containing protein 1