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PTGR2 encodes an enzyme involved in the metabolism of prostaglandins. Additionally we are shipping PTGR2 Antibodies (62) and PTGR2 Proteins (12) and many more products for this protein.
Silencing of PTGR2 expression enhances reactive oxygen species production, suppresses pancreatic cell proliferation, and promotes cell death through increasing 15-keto-PGE2.
Functional data and clinical relevance for the role of PTGR2 in gastric cancer, are provided.
Besides targeting cyclooxygenase, indomethacin inhibits PTGR2 with a binding mode similar to that of 15-keto-PGE (show LIPF ELISA Kits)(2).
This mouse gene encodes a putative NADPH-dependent oxidoreductase. We report the crystal structure of the putative oxidoreductase determined by the semi-automated high-throughput pipeline of the Joint Center for Structural Genomics
15-oxoprostaglandin-Delta13-reductase (PGR-2) catalyzes the reaction converting 15-keto-PGE2 to 13,14-dihydro-15-keto-PGE2
This gene encodes an enzyme involved in the metabolism of prostaglandins. The encoded protein catalyzes the NADPH-dependent conversion of 15-keto-prostaglandin E2 to 15-keto-13,14-dihydro-prostaglandin E2. This protein may also be involved in regulating activation of the peroxisome proliferator-activated receptor. Alternative splicing results in multiple transcript variants.
zinc binding alcohol dehydrogenase, domain containing 1
, prostaglandin reductase 2
, Zinc-binding alcohol dehydrogenase domain-containing protein 1
, 15-oxoprostaglandin 13-reductase
, zinc-binding alcohol dehydrogenase domain-containing protein 1