You are viewing an incomplete version of our website. Please click to reload the website as full version.

Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) Proteins (PTGS1)

This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. Additionally we are shipping PTGS1 Antibodies (127) and PTGS1 Kits (62) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PTGS1 19224 P22437
PTGS1 24693 Q63921
PTGS1 5742 P23219
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top PTGS1 Proteins at antibodies-online.com

Showing 9 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$904.20
Details
HOST_Escherichia coli (E. coli) Rat His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$809.60
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$880.00
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$246.96
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,653.83
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$1,077.90
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 19 Days
$785.40
Details

PTGS1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus) ,
,
Human , ,
, ,

More Proteins for Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1) Interaction Partners

Horse (Equine) Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1) interaction partners

  1. This study showed that COX-1 and COX-2 (show PTGS2 Proteins) in genital carcinomas in the horse is poor; microsomal PGES (show PTGES Proteins)-1 is more prominently expressed.

  2. COX-1 and COX-2 (show PTGS2 Proteins) genes were constitutively expressed in baseline samples. Low-flow ischemia resulted in significant upregulation of COX-2 (show PTGS2 Proteins) gene expression at each subsequent time point, compared with baseline values.

  3. In this study, both COX-1 and COX-2 (show PTGS2 Proteins) were expressed in the colon before induced ischemia; ischemic injury increased expression of COX-2 (show PTGS2 Proteins).

  4. Immunoreactivity for COX-1 and COX-2 (show PTGS2 Proteins) is high in equine corneal SCC (show CYP11A1 Proteins), possibly indicating that COX (show CPOX Proteins) plays a role in oncogenesis or progression of this tumor type at this site.

Mouse (Murine) Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1) interaction partners

  1. role of cyclooxygenase-1 and -2 in endothelium-dependent contraction of atherosclerotic mouse abdominal aortas

  2. Suggest the expression of COX-1 and COX-2 in the urothelium protects bladder damage from radiation.

  3. COX-1 inhibitor SC-560 has a protective effect on the thromboxane A2-mediated decrease in renal function in response to endotoxin.

  4. Expression of COX-1 is essential for the protection of liver against chemical-induced hepatotoxicity and required for hepatic homeostatic maintenance.

  5. Data suggest that multitarget FAAH (show FAAH Proteins)/Cox (show CPOX Proteins) blockade may provide a transformative approach to inflammatory bowel disease (IBD) and other pathologies in which fatty acid amide hydrolase (show FAAH Proteins)/cyclooxygenases (FAAH (show FAAH Proteins), Cox-1, and Cox-2) are overactive.

  6. In arteries from non-insulin (show INS Proteins)-dependent diabetic mice, COX-1 remains a major contributor to the endothelial PGI2 (show PTGIR Proteins) synthesis that evokes vasoconstrictor activity under the pathological condition.

  7. specific inhibition of mmu-miR (show MLXIP Proteins)-100-5p significantly enhanced expression of Il6 (show IL6 Proteins), Ptgs1/2 and Tlr4 (show TLR4 Proteins) mRNA

  8. COX1/2-derived prostanoids appear to play an important role in the TLR response, with elevated cytokine levels following COX1/2 inhibition or genetic deletion.

  9. Data suggest deletion of Cox1 delays ovarian follicle development prior to reproductive maturation of mutant mouse strain (Wv); inhibition of Cox1 (but not Cox2) may prolong ovarian follicle lifespan and delay the onset of premature ovarian failure.

  10. role of COX-1 during maturation of adipocyte

Cow (Bovine) Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1) interaction partners

  1. there was no expression of COX-1, either mRNA or protein, on any day of the estrous cycle

Human Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1) interaction partners

  1. In Indian peptic ulcer hemorrhage patients, those with Cox-1 A842G polymorphisms tended to have less gastric ulcers among those with the A842G/C50T polymorphism.

  2. inverse allosteric regulation likely underlies the ability of PGHS-2 (show PTGS2 Proteins) to operate at low AA concentrations, when PGHS-1 is effectively latent.

  3. PON1 (show PON1 Proteins), P2Y12 (show P2RY12 Proteins) and COX1 polymorphisms were associated with poorer vascular outcomes in patients with extracranial or intracranial stents.

  4. The regulation of important oxylipin metabolic genes in peripheral blood mononuclear cells varied with the extent of change in arachidonic acid concentrations in the case of PTGS1 and ALOX12 (show ALOX12 Proteins) regulation.

  5. Immunohistochemical expression of COX-1 and VEGF (show VEGFA Proteins) is associated with poor prognostic parameters in renal cell carcinoma (show MOK Proteins).

  6. over-expression of COX-1 in an aberrant manner intersects multiple pro-tumorigenic pathways in high-grade serous ovarian cancer

  7. COX-2 displays an enhanced facilitatory control on tachykininergic contractile activity in diverticular disease

  8. Significant associations with NSAID-exacerbated respiratory disease were identified for: ALOX15 (show ALOX15 Proteins) homozygous genotype and PTGS-1 rs5789 A/A homozygous genotype

  9. Origin of the Enigmatic Stepwise Tight-Binding Inhibition of Cyclooxygenase-1.

  10. cadmium at the highest tested concentrations modulates COX-1 and COX-2 at mRNA level in THP-1 macrophages

Pig (Porcine) Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1) interaction partners

  1. Brain death increases the expression of COX-1 and COX-2 (show PTGS2 Proteins) mRNA in the renal medulla

  2. Endometrial prostaglandin-endoperoxide synthase 1 (PTGS1) mRNA expression increased 2- to 3-fold after Day 10 of the estrous cycle and pregnancy, whereas PTGS2 (show PTGS2 Proteins) mRNA expression increased 76-fold between Days 5 and 15 of the estrous cycle and pregnancy.

PTGS1 Protein Profile

Protein Summary

This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with PTGS1

  • prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (PTGS1)
  • cyclooxygenase-1 (cox-1)
  • cyclooxygenase-1 (COX-1)
  • prostaglandin-endoperoxide synthase 1 (Ptgs1)
  • prostaglandin-endoperoxide synthase 1 (ptgs1)
  • prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (ptgs1)
  • Cox-1 protein
  • COX-3 protein
  • cox1 protein
  • COX3 protein
  • PCOX1 protein
  • PES-1 protein
  • PGG/HS protein
  • PGHS-1 protein
  • PGHS1 protein
  • PHS1 protein
  • PHS 1 protein
  • PTGHS protein
  • Ptgs1 protein
  • zCOX-1 protein

Protein level used designations for PTGS1

cyclooxygenase-1 , prostaglandin G/H synthase 1 , prostaglandin G/H synthase and cyclooxygenase , prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) , PGH synthase 1 , PGHS-1 , PHS 1 , prostaglandin H2 synthase 1 , prostaglandin-endoperoxide synthase 1 , cyclooxygenase 1 , COX-1 , cyclooxygenase 3 , Cox-1 , Cox-1b , prostaglandin endoperoxide synthase , cyclooxygenase

GENE ID SPECIES
100034087 Equus caballus
100136038 Oncorhynchus mykiss
427752 Gallus gallus
464713 Pan troglodytes
698213 Macaca mulatta
100585600 Nomascus leucogenys
100009407 Oryctolagus cuniculus
19224 Mus musculus
24693 Rattus norvegicus
246226 Danio rerio
282022 Bos taurus
5742 Homo sapiens
443551 Ovis aries
403544 Canis lupus familiaris
397541 Sus scrofa
100037245 Xenopus laevis
Selected quality suppliers for PTGS1 Proteins (PTGS1)
Did you look for something else?