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anti-Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2) Antibodies

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. Additionally we are shipping Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) Kits (77) and Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PTGS2 19225 Q05769
PTGS2 29527 P35355
PTGS2 5743 P35354
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Top anti-Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) Antibodies at antibodies-online.com

Showing 10 out of 215 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Western blot analysis of Cox-2 expression in Jurkat cell lysates. 100 μg Log in to see 2 to 3 Days
$283.50
Details
Mouse Rabbit Un-conjugated IHC (p) Formalin fixed paraffin embedded human colon carcinoma stained with CO... 1 mL Log in to see 6 to 8 Days
$676.50
Details
Human Rabbit Un-conjugated IHC (p) 7 mL Log in to see 2 to 3 Days
$280.00
Details
Cow Goat Un-conjugated EIA, WB 20 μg Log in to see 6 to 8 Days
$203.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Confocal immunofluorescent analysis of PTGS2 Antibody (Center P378) (A... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB Confocal immunofluorescent analysis of Cyclooxygenase 2 Antibody (Cent... Formalin fixed and paraffin embedded human uterus tissue stained with ... 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p) 1 mL Log in to see 2 to 3 Days
$507.00
Details
Human Goat Un-conjugated ELISA, WB ABIN184672 staining (0.5µg/ml) of H460 lysate (RIPA buffer, 35µg total... 100 μg Log in to see 4 to 5 Days
$318.20
Details
Chicken Mouse Biotin WB Western blot analysis of Cox-2 on lysate from mouse macrophages treate... 50 μg Log in to see 5 to 6 Days
$341.03
Details
Chicken Mouse Un-conjugated IF, IP, IHC, WB Western blot analysis of Cox-2 on a lysate from mouse macrophages trea... Immunofluoresence staining of mouse macrophages. 50 μg Log in to see 5 to 6 Days
$205.42
Details

PTGS2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
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Top referenced anti-Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) Antibodies

  1. Human Monoclonal PTGS2 Primary Antibody for IHC (p) - ABIN1687606 : Yang, Hsu, Meng, Su: Supplement of 5-hydroxytryptophan before induction suppresses inflammation and collagen-induced arthritis. in Arthritis research & therapy 2015 (PubMed)
    Show all 29 references for ABIN1687606

  2. Human Monoclonal PTGS2 Primary Antibody for IHC (p) - ABIN1687611 : Carvalho, Pires, Prada, Ferreira, Queiroga: Positive Interplay Between CD3+ T-lymphocytes and Concurrent COX-2/EGFR Expression in Canine Malignant Mammary Tumors. in Anticancer research 2015 (PubMed)
    Show all 24 references for ABIN1687611

  3. Chicken Monoclonal PTGS2 Primary Antibody for WB - ABIN967824 : Hla, Neilson: Human cyclooxygenase-2 cDNA. in Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)
    Show all 5 references for ABIN967824

  4. Chicken Monoclonal PTGS2 Primary Antibody for IF, IP - ABIN967822 : Marrogi, Pass, Khan, Metheny-Barlow, Harris, Gerwin: Human mesothelioma samples overexpress both cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (NOS2): in vitro antiproliferative effects of a COX-2 inhibitor. in Cancer research 2000 (PubMed)
    Show all 5 references for ABIN967822

  5. Human Polyclonal PTGS2 Primary Antibody for EIA, IF - ABIN951767 : Duggan, Walters, Musee, Harp, Kiefer, Oates, Marnett: Molecular basis for cyclooxygenase inhibition by the non-steroidal anti-inflammatory drug naproxen. in The Journal of biological chemistry 2010 (PubMed)
    Show all 4 references for ABIN951767

  6. Mouse (Murine) Polyclonal PTGS2 Primary Antibody for IHC (p) - ABIN115419 : Cras, Martin, Gheuens: Gamma-enolase and glial fibrillary acidic protein in nervous system tumors. An immunohistochemical study using specific monoclonal antibodies. in Acta neuropathologica 1988 (PubMed)
    Show all 2 references for ABIN115419

  7. Human Polyclonal PTGS2 Primary Antibody for ELISA, WB - ABIN184672 : Ballif, Mincek, Barratt, Wilson, Simmons: Interaction of cyclooxygenases with an apoptosis- and autoimmunity-associated protein. in Proceedings of the National Academy of Sciences of the United States of America 1996 (PubMed)

  8. Human Polyclonal PTGS2 Primary Antibody for WB - ABIN223087 : Majed, Rashid, Khan, Nafees, Ali, Ali, Khan, Hasan, Mehdi, Sultana: Tannic acid mitigates the DMBA/croton oil-induced skin cancer progression in mice. in Molecular and cellular biochemistry 2014 (PubMed)

More Antibodies against Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) Interaction Partners

Horse (Equine) Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2) interaction partners

  1. This study showed that COX-1 (show PTGS1 Antibodies) and COX-2 in genital carcinomas in the horse is poor; microsomal PGES (show PTGES Antibodies)-1 is more prominently expressed.

  2. Progestin treatment does not affect expression of cytokines, steroid receptors, oxytocin receptor (show OXTR Antibodies), and cyclooxygenase 2 in fetal membranes and endometrium.

  3. COX-1 (show PTGS1 Antibodies) and COX-2 genes were constitutively expressed in baseline samples. Low-flow ischemia resulted in significant upregulation of COX-2 gene expression at each subsequent time point, compared with baseline values.

  4. The role for p38 (show MAPK14 Antibodies) mitogen-activated kinase (MAPK (show MAPK1 Antibodies)) in the signaling mechanism regulating pro-inflammatory cyclooxygenase (COX (show CPOX Antibodies)) gene expression in lipopolysaccharide (LPS (show IRF6 Antibodies))-activated equine leukocytes in horses is reported.

  5. In this study, both COX-1 (show PTGS1 Antibodies) and COX-2 were expressed in the colon before induced ischemia; ischemic injury increased expression of COX-2.

  6. Immunoreactivity for COX-1 (show PTGS1 Antibodies) and COX-2 is high in equine corneal SCC (show CYP11A1 Antibodies), possibly indicating that COX (show CPOX Antibodies) plays a role in oncogenesis or progression of this tumor type at this site.

  7. It was found that most equine squamous-cell carcinomas and many melanomas appear to express COX-2 and thus could respond to COX-2 inhibitor therapy.

  8. data support the hypothesis that prostaglandin G/H synthase 2(PGHS2)is a target for the antiluteolytic signal produced by equine conceptuses during early pregnancy

Cow (Bovine) Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2) interaction partners

  1. results indicate that nuclear receptor subfamily 1 group D member 1(REV-ERBalpha (show NR1D1 Antibodies)) plays an inhibitory role in the expression of prostaglandin-endoperoxide synthase 2(PTGS2) in both bovine USCs and UECs treated with ovarian steroids

  2. This study showed that neutrophils from periparturient heifers show impairment of COX-2 mRNA expression and lactoferrin (show LTF Antibodies), suggesting that these mechanisms may contribute to immunosuppression in cows around calving.

  3. Exposure to follicular fluid transiently increased the transcript levels of IL8 (show IL8 Antibodies) and PTGS2, and decreased the expression of SOD2 (show SOD2 Antibodies), GPX3 (show GPX3 Antibodies), DAB2 (show DAB2 Antibodies), and NR3C1 (show NR3C1 Antibodies). TNF (show TNF Antibodies) and IL6 (show IL6 Antibodies) levels were also decreased while those of NAMPT (show NAMPT Antibodies) were unaffected.

  4. Purinergic P2Y1 receptor (show P2RY1 Antibodies) signaling mediates wound stimuli-induced cyclooxygenase-2 expression in intestinal subepithelial myofibroblasts

  5. Data suggest that Escherichia coli infections (here, administration of LPS (show IRF6 Antibodies)) provokes luteolysis in diestrus, non-lactating cows but no change in expression of PTGS2 in corpus luteum and has no effect on luteinization in the following cycle.

  6. This study is the first to report the involvement of PGE2 in oocyte MAPK (show MAPK1 Antibodies) activation during the maturation process.

  7. Inhibitors of c-Src (show SRC Antibodies) (PP2, 10 microm) and PI3K (LY294002, 25 microm) produced a significant decrease in oxytocin-induced PGF (show PGF Antibodies)(2 alpha) production and reduced COX2 expression by endometrial epithelial cells.

  8. COX-2 pathway is responsible for the endometrial production of PGE (show LIPF Antibodies)(2) in the bovine endometrium during the estrous cycle

  9. the conceptus, through its secretion of IFN-tau, stimulates maternal epithelial expression of COX-2 and GM-CSF (show CSF2 Antibodies) during the peri (show PLIN1 Antibodies)-attachment period in the cow.

  10. the PGHS-2 promoter is regulated by bovine upstream stimulatory factor 1 (show USF1 Antibodies) and 2 in preovulatory granulosa cells

Mouse (Murine) Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2) interaction partners

  1. Suggest the expression of COX-1 (show PTGS1 Antibodies) and COX-2 (show COX2 Antibodies) in the urothelium protects bladder damage from radiation.

  2. Ptgs2 mRNAs increased within 5 h after injury in mouse cortical slices.

  3. Modulation of COX-2 (show COX2 Antibodies)-driven metabolization of 2-AG may provide a novel physiological concept allowing the specific targeting of HSCs in liver fibrosis.

  4. alveolar type II cell-derived COX-2 (show COX2 Antibodies) plays an important role in regulating basal airway function and LPS (show TLR4 Antibodies)-induced lung inflammation

  5. COX2 (show COX2 Antibodies) is involved in hypoxia-induced TNF-alpha (show TNF Antibodies) expression in osteoblast.

  6. The ERK5 (show MAPK7 Antibodies) pathway is essential in the induction of COX-2 (show COX2 Antibodies) gene.

  7. 11betaHSD2 inhibition suppressed lung tumor growth and invasion in association with increased tissue active glucocorticoid levels, decreased COX-2 (show COX2 Antibodies) expression, inhibition of ERK (show EPHB2 Antibodies) and mTOR (show FRAP1 Antibodies) signaling pathways.

  8. COX-2 (show COX2 Antibodies) and EP-2 (show SPAG11A Antibodies) signaling contribute significantly to the heart leukocyte infiltration and to the release of chemokines and inflammatory cytokines in the heart of T. cruzi infected mice.

  9. Data show that the activation of mammalian target of rapamycin (show FRAP1 Antibodies) complex mTORC1 during encephalomyocarditis virus infection is chemokine (C-C) receptor 5-dependent and promotes the translation of inducible NO synthase (iNOS (show NOS2 Antibodies)) and cyclooxygenase (COX)-2 (show COX2 Antibodies).

  10. Results suggest that substrates interact with cyclooxygenase-2 (COX-2) via multiple potential complexes involving binding to both the catalytic and allosteric sites.

Human Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2) interaction partners

  1. G6PD (show G6PD Antibodies) deficiency affects the cellular inflammatory response and the decreased TNF-alpha (show TNF Antibodies)-mediated antiviral response in G6PD (show G6PD Antibodies)-kd A549 cells is a result of dysregulated NOX/MAPK (show MAPK1 Antibodies)/NF-kappaB (show NFKB1 Antibodies)/COX-2 (show COX2 Antibodies) signaling

  2. these results suggest that targeting the COX-2 (show COX2 Antibodies)/PGE2 pathway together with TLR/MyD88 (show MYD88 Antibodies) signaling, which would suppress the inflammatory microenvironment and maintenance of stemness, could be an effective preventive or therapeutic strategy for gastric cancer

  3. Downregulation of RhoGDI (show ARHGDIA Antibodies) could be a critical mechanism of breast tumor development, which may involve the hyperactivation of Rho GTPases and upregulation of COX-2 (show COX2 Antibodies) activity.

  4. Low PTGS2 expression is associated with Uterine Carcinosarcoma.

  5. Data suggest that cyclooxygenase 2 (COX-2) functions as a key cancer promoting factor by triggering a positive-feedback loop between macrophages and cancer cells.

  6. Determined are the crystal structures of S530T murine (mu) COX-2 (show COX2 Antibodies), aspirin-acetylated human (hu) COX-2 (show COX2 Antibodies), and huCOX-2 in complex with salicylate to 1.9, 2.0, and 2.4 A, respectively.

  7. Decreased capacity of fibrotic lung fibroblasts to up-regulate COX-2 expression and COX-2-derived PGE2 synthesis is due to an indirect epigenetic mechanism involving hypermethylation of the transcriptional regulator, c8orf4.

  8. COX-2 (show COX2 Antibodies) and Ki-67 (show MKI67 Antibodies) are abundantly expressed in hepatolithiasis and bile duct carcinoma tissues and may play an important role in the disease occurrence, progression, and metastasis

  9. The present study identified that in Brazilian women the presence of the ancestral allele, -765G, of the COX-2 (show COX2 Antibodies) gene is associated with an increased risk for development of moderate/severe endometriosis associated with fertility.

  10. inverse allosteric regulation likely underlies the ability of PGHS-2 to operate at low AA concentrations, when PGHS-1 (show PTGS1 Antibodies) is effectively latent.

Pig (Porcine) Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2) interaction partners

  1. These findings suggest that nuclear factor kappa B(NF-kappaB (show NFKB1 Antibodies)) and cyclooxygenase-2 play roles in epidermal cell regeneration following beta-irradiation of mini-pig skin.

  2. COX2 expression is upregulated in CAVD, and its activity contributes to osteogenic gene induction and valve calcification in vitro and in vivo.

  3. These results suggest that COX-2 plays a role in the pathogenesis of Mycoplasma hyopneumoniae -infection.

  4. Brain death increases the expression of COX-1 (show COX1 Antibodies) and COX-2 mRNA in the renal medulla

  5. COX-2 is differentially expressed in normal versus lungworm-infected lungs of pigs and is likely to be involved in the pathogenesis of porcine parasitic bronchopneumonia.

  6. In porcine vas (show AVP Antibodies) deferens epithelial cell monolayers, increases in anion secretion were associated with preferential upregulation of PTGS2 at the mRNA and protein levels.

  7. expression appears to be positively and negatively regulated by p38 MAPK (show MAPK14 Antibodies) and JNK (show MAPK8 Antibodies) pathways; alternatively, ERK1/2 (show MAPK1/3 Antibodies) appear to be involved in COX-2-independent reparative events that remain to be defined

  8. Neutrophils augment recovery of transepithelial electrical resistance in ischemia-injured ileal mucosa via IL-1beta (show IL1B Antibodies)-dependent upregulation of COX-2. (Cyclooxygenase 2)

  9. Administration of estrogen early in pregnancy alters endometrial prostaglandin-endoperoxide synthase 2 (PTGS2) mRNA and protein expression, which may disrupt pregnancy causing total embryonic loss during implantation in the pig.

  10. The effect of EGF (show EGF Antibodies) on pro-inflammatory cytokines, tumor necrosis factor-alpha (TNF-alpha (show TNF Antibodies)) and cyclooxygenase-2 (COX-2), levels during wound healing in swine is reported.

Rabbit Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2) interaction partners

  1. results revealed that a transient episode of raised-intensity phonation causes a significant increase in vocal fold inflammatory mRNA expression - IL-1beta (show IL1B Antibodies),COX-2 (show COX2 Antibodies), and TGFbeta1 (show TGFB1 Antibodies)

  2. The result demonstrate that mechanical stress on synovial cells induces gene expressions of COX-2 (show COX2 Antibodies).

  3. Diabetes enhances the vasodilator response of the rabbit carotid artery to testosterone by a mechanism that includes an increased modulatory activity of the endothelial nitric oxide and an augmented release of COX-2 (show COX2 Antibodies) vasodilator, prostacyclin.

  4. Local induction of COX-2 (show COX2 Antibodies) during atherosclerosis decreased the sensitivity to norepinephrine and that COX-2 (show COX2 Antibodies) inhibitors may increase vascular reactivity at sites of atherosclerotic lesions.

Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2) Antigen Profile

Protein Summary

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.

Gene names and symbols associated with PTGS2

  • cyclooxygenase-2 (COX-2) antibody
  • prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (PTGS2) antibody
  • cyclooxygenase-2 (cox-2) antibody
  • cyclooxygenase 2 (cox-2) antibody
  • prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (ptgs2) antibody
  • cytochrome c oxidase subunit II (COX2) antibody
  • olfactory receptor, family 2, subfamily W, member 1-like (LOC782475) antibody
  • prostaglandin-endoperoxide synthase 2 (Ptgs2) antibody
  • CEF147 antibody
  • COII antibody
  • Cox-2 antibody
  • Cox2 antibody
  • GRIPGHS antibody
  • hCox-2 antibody
  • PGG/HS antibody
  • PGHS-2 antibody
  • PGHS2 antibody
  • PHS-2 antibody
  • PHSII antibody
  • PTGS2 antibody
  • TIS10 antibody

Protein level used designations for PTGS2

cyclooxygenase-2 , cyclooxygenase 2 , prostaglandin G/H synthase 2 , prostaglandin G/H synthase and cyclooxygenase , prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) , prostaglandin G/H synthase 2-like , PES-2 , PGH synthase 2 , PHS II , glucocorticoid-regulated inflammatory cyclooxygenase , gripghs , macrophage activation-associated marker protein P71/73 , prostaglandin H2 synthase 2 , PGHS-2 , cyclooxygenase 2b , COX-2 , prostaglandin G/H synthase-2 , cyclooxygenase, prostaglandin endoperoxide H synthase-2 , prostaglandin H synthase-2 , cyclooxygenase type 2 , mitogen-inducible PGHS

GENE ID SPECIES
100033836 Equus caballus
100126581 Felis catus
100136025 Oncorhynchus mykiss
100136456 Salmo salar
446781 Xenopus laevis
469616 Pan troglodytes
595089 Xenopus (Silurana) tropicalis
716671 Macaca mulatta
100407639 Callithrix jacchus
100436566 Pongo abelii
807845 Equus caballus
808252 Ovis aries
782475 Bos taurus
19225 Mus musculus
29527 Rattus norvegicus
100135607 Cavia porcellus
5743 Homo sapiens
282023 Bos taurus
791253 Equus caballus
443460 Ovis aries
442942 Canis lupus familiaris
397590 Sus scrofa
100009248 Oryctolagus cuniculus
396451 Gallus gallus
100860905 Capra hircus
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