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PSCA encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. Additionally we are shipping Prostate Stem Cell Antigen Antibodies (102) and Prostate Stem Cell Antigen Kits (8) and many more products for this protein.
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analysis of PSCA level in the peripheral blood of PC patients who underwent radical prostatectomy shows it is related to a GADPH (show GAPDH Proteins) reference level (PSCA/GAPDH (show GAPDH Proteins) ratio)
our data provide a novel molecular mechanism for the tumor suppressor role of PSCA
suggest that PSCA is a useful tissue marker for predicting biochemical recurrence in patients with high risk PC receiving NHT and radical prostatectomy
Genetic Variants of PSCA Gene are not Associated with Colorectal Cancer.
we show that PSCA is a key player in nasopharyngeal carcinoma metastasis
PSCA rs2294008 Polymorphism is associated with Increased Risk of Cancer
PSCA has a promoting role in the growth and metastasis of prostate cancer.
PSCA mRNA is overexpressed in the peripheral blood of prostate cancer patients.
These results suggest that PSCA gene variation has a potential effect on its expression and gastric adenocarcinoma risk in the Northwest Chinese population.
a significantly increased stomach cancer risk was associated with PSCA SNPs rs2294008 and s2976392 in a Han Chinese population.
Increase in prostate stem cell antigen expression in prostatic hyperplasia induced by testosterone and 17beta-estradiol in C57BL mice
This transgenic system helps define the range of cellular changes associated with altered expression of PSCA, shows that transcriptional control is a major component regulating PSCA levels.
Sca-1-enriched prostate-regenerating cells possess multiple stem/progenitor cell properties
PSCA may play a role in limiting prostate tumor progression in certain contexts, and deletion of PSCA may promote tumor migration and metastasis.
This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals\; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants.
prostate stem cell antigen