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anti-Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1) Antibodies

PMEPA1 encodes a transmembrane protein that contains a Smad interacting motif (SIM). Additionally we are shipping PMEPA1 Proteins (8) and PMEPA1 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PMEPA1 311676  
PMEPA1 56937 Q969W9
PMEPA1 65112  
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Top anti-PMEPA1 Antibodies at antibodies-online.com

Showing 10 out of 25 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB Immunofluorescence analysis of HuvEc cells, using TMEPA Antibody. The picture on the right is treated with the synthesized peptide. Human Prostate, Smooth Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated DB, EIA, WB   0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged TMEPAI is approximately 1ng/ml as a capture antibody. Western Blot detection against Immunogen (36.74 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IF, IHC (p), ELISA, WB Anti-PMEPA1 antibody IHC staining of human prostate, smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN959365 concentration 10 ug/ml. 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of PMEPA1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of PMEPA1 expression in PC3 (A) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA, WB   0.1 mg Log in to see 2 to 3 Days
$330.00
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged TMEPAI is approximately 1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Un-conjugated ELISA, IF, IHC, WB 100 μL Log in to see 14 Days
$201.19
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details

PMEPA1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus)


Human ,
,
,

Mouse (Murine)


Top referenced anti-PMEPA1 Antibodies

  1. Human Monoclonal PMEPA1 Primary Antibody for ELISA, WB - ABIN566055 : Hirokawa, Takagi, Uchida, Kozuka, Yoneda, Watanabe, Shiraishi: High level expression of STAG1/PMEPA1 in an androgen-independent prostate cancer PC3 subclone. in Cellular & molecular biology letters 2012 (PubMed)
    Show all 8 references for ABIN566055

  2. Human Polyclonal PMEPA1 Primary Antibody for EIA, IF - ABIN954212 : Li, Xu, Masuda, Raymundo, McLeod, Dobi, Srivastava: A feedback loop between the androgen receptor and a NEDD4-binding protein, PMEPA1, in prostate cancer cells. in The Journal of biological chemistry 2008 (PubMed)
    Show all 2 references for ABIN954212

  3. Human Polyclonal PMEPA1 Primary Antibody for DB, EIA - ABIN493520 : Richter, Masuda, Cook, Ehrich, Tadese, Li, Owusu, Srivastava, Dobi: A role for DNA methylation in regulating the growth suppressor PMEPA1 gene in prostate cancer. in Epigenetics : official journal of the DNA Methylation Society 2008 (PubMed)
    Show all 2 references for ABIN493520

More Antibodies against PMEPA1 Interaction Partners

Human Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1) interaction partners

  1. these data elaborated on the diverse activity among TCF (show HNF4A Antibodies)/LEF family members with respect to the transcriptional regulation of the TMEPAI gene.

  2. Data show that over-expressed transmembrane prostate androgen-induced protein 1 (PMEPA1) can promote cell migration and maintain the mesenchymal-like morphology of breast cancer cells.

  3. Data show that silencing of PMEPA1 protein facilitates the growth of prostate cancer cells and modulates androgen receptor (AR (show AR Antibodies)) through NEDD4 (show NEDD4 Antibodies) ubiquitin protein ligase (show UBE2K Antibodies) and PTEN (show PTEN Antibodies) protein.

  4. Downregulation of PMEPA1 may result in increased androgen receptor (show AR Antibodies) protein levels and function in cancer of the prostate cells, contributing to prostate tumorigenesis.

  5. EGF (show EGF Antibodies) signaling collaboratively regulates TGF-beta (show TGFB1 Antibodies)-induced TMEPAI expression.

  6. TMEPAI is translocated on the lysosome and late endosome, and that association with Nedd4 (show NEDD4 Antibodies) is required for the transport of TMEPAI to the lysosome.

  7. TMEPAI promotes tumorigenic activities in lung cancer cells.

  8. The levels of TMEPAI in lung tumor tissues are very high.

  9. Differentially expressed genes were identified, including E-cadherin (show CDH1 Antibodies), IL-8 (show IL8 Antibodies) and STAG1/PMEPA1 in an androgen-independent prostate cancer PC3 (show PCSK1 Antibodies) subclone.

  10. Results suggest that TMEPAI functions in breast cancer as a molecular switch that converts TGF-beta (show TGFB1 Antibodies) from a tumor suppressor to a tumor promoter.

Mouse (Murine) Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1) interaction partners

  1. Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies)/TCF7L2 (show TCF7L2 Antibodies) pathway is preferentially able to alter the transcriptional regulation of the TGF-beta (show TGFB1 Antibodies)-target gene, TMEPAI.

PMEPA1 Antigen Profile

Protein Summary

This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with PMEPA1

  • prostate transmembrane protein, androgen induced 1 (Pmepa1) antibody
  • prostate transmembrane protein, androgen induced 1 (PMEPA1) antibody
  • prostate transmembrane protein, androgen induced 1 (pmepa1) antibody
  • transmembrane, prostate androgen induced RNA (tmepai) antibody
  • 2210418I02Rik antibody
  • AW455466 antibody
  • Erg1.2 antibody
  • N4wbp4 antibody
  • PMEPA1 antibody
  • Stag1 antibody
  • tmepai antibody
  • zgc:92731 antibody

Protein level used designations for PMEPA1

transmembrane prostate androgen-induced protein , transmembrane, prostate androgen induced RNA , prostate transmembrane protein, androgen induced 1 , solid tumor-associated 1 protein , NEDD4 WW domain-binding protein 4 , Nedd4 WW binding protein 4

GENE ID SPECIES
311676 Rattus norvegicus
428166 Gallus gallus
436853 Danio rerio
485945 Canis lupus familiaris
617469 Bos taurus
100137708 Xenopus laevis
100144523 Sus scrofa
56937 Homo sapiens
65112 Mus musculus
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