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Protamine 2 Proteins (PRM2)

Protamines are the major DNA-binding proteins in the nucleus of sperm, and package the DNA in a volume less than 5% of a somatic cell nucleus (summarized by Cho et al., 2001 [PubMed 11326282]). Additionally we are shipping Protamine 2 Kits (11) and Protamine 2 Antibodies (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PRM2 19119 P07978
PRM2 25345 P11248
PRM2 5620 P04554
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Top Protamine 2 Proteins at antibodies-online.com

Showing 10 out of 25 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Snail His tag   1 mg Log in to see 56 to 66 Days
$2,044.17
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,150.50
Details
Yeast REACT_Howler monkey His tag   1 mg Log in to see 56 to 66 Days
$2,174.33
Details
Yeast Pan troglodytes His tag   1 mg Log in to see 56 to 66 Days
$2,181.67
Details
Yeast Pan paniscus His tag   1 mg Log in to see 56 to 66 Days
$2,181.67
Details
Yeast Pongo pygmaeus His tag   1 mg Log in to see 56 to 66 Days
$2,181.67
Details
Yeast Primate His tag   1 mg Log in to see 56 to 66 Days
$2,185.33
Details

PRM2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus)

Human , ,
,

More Proteins for Protamine 2 (PRM2) Interaction Partners

Mouse (Murine) Protamine 2 (PRM2) interaction partners

  1. In CBF-A (show CEBPA Proteins) knockout mice, expression of protamine 2 (PRM2) was reduced and the Prm2 mRNA was prematurely translated in a subset of elongating spermatids.

  2. Testis-specific (show AIF1 Proteins) miRNA-469 up-regulated in gonadotropin-regulated testicular RNA helicase (GRTH/DDX25 (show DDX25 Proteins))-null mice silences transition protein 2 and protamine 2 messages at sites within coding region: implications of its role in germ cell development.

  3. direct correlation between the fraction of sperm with haploinsufficiency of PRM2 and the frequency of sperm with damaged DNA. Ultrastructural analysis revealed reduced compaction of the chromatin

  4. Germ cell nuclear factor (show NR6A1 Proteins) acts as a repressor of basal transcription on both the Protamine 1 (show PRM1 Proteins) and Protamine 2 promoters.

  5. Study shows that protamine 1 (show PRM1 Proteins) and 2 mRNAs, which are specific to the round spermatid stage, are repressed at the two-pronuclei and two-cell stages postfertilization, respectively, in embryos created by round spermatid injection, by distinct mechanisms.

Cow (Bovine) Protamine 2 (PRM2) interaction partners

  1. This study was conducted to isolate high-quality RNA from mature spermatozoa and to monitor the expression profile of PRM1 (show PRM1 Proteins) and PRM2 gene in ejaculated spermatozoa of normal and motility impaired bulls.

Pig (Porcine) Protamine 2 (PRM2) interaction partners

  1. Porcine spermatozoa may delivery CLU (show CLU Proteins), PRM1 (show PRM1 Proteins) and PRM2 mRNAs to the oocyte, which may contribute to zygotic and early embryonic development.

Human Protamine 2 (PRM2) interaction partners

  1. PRM2 gene expression was significantly decreased in immature sperm extracted from the fertile and infertile groups. Caspase 9 (show CASP9 Proteins) activity was significantly increased in immature sperm extracted from both groups.

  2. the quantity of PRM1 (show PRM1 Proteins), PRM2, and TNP2 (show TNP2 Proteins) transcripts and the PRM1 (show PRM1 Proteins)/PRM2 mRNA ratio affect spermiogenesis, sperm morphology

  3. Data indicate changed ecpression levels of PRM2, HSP90 (show HSP90 Proteins) and WNT5A (show WNT5A Proteins) in male of couples experiencing idiopathic recurrent miscarriages.

  4. Single nuclotide polymorphisms in PRM2 gene is associated with male infertility.

  5. significant correlation has been found between protamine 1 (show PRM1 Proteins) and 2 transcripts/proteins and: sperm concentration, progressive sperm motility, sperm fertilization ability as well as embryo quality

  6. identified and we report for the first time five novel rare haplotypes encompassing the protamine 1 (show PRM1 Proteins) and 2 genes

  7. Data suggest that Casp4 (show CASP4 Proteins), Casp 6 (show CASP6 Proteins) and TNFSF10 (show TNFSF10 Proteins) are differentially expressed in potentially fertile and subfertile men and represent useful biomarkers for predicting male fertility in combination with P1 and P2.

  8. analyse the presence of DAZ, RBMY1, USP9Y, protamine-2, SRY and actin messenger RNA (mRNA) in testicular cells of men suffering from idiopathic azoospermia.

  9. A number of SNPs are present in the testis-specific nuclear protein genes.

  10. Novel polycythemia vera (show IGF2BP3 Proteins) (PV)-associated tumor antigen PV13 (protamine 2) elicits IgG antibody reactions in a subset of PV patients but not in healthy donors, suggesting that it is an authentic tumor antigens.

Protamine 2 (PRM2) Protein Profile

Protein Summary

Protamines are the major DNA-binding proteins in the nucleus of sperm, and package the DNA in a volume less than 5% of a somatic cell nucleus (summarized by Cho et al., 2001

Gene names and symbols associated with Protamine 2 Proteins (PRM2)

  • protamine 2 (Prm2)
  • protamine 2 (PRM2)
  • AI528784 protein
  • CT94.2 protein
  • P2 protein
  • Prm-2 protein
  • PROTA2 protein

Protein level used designations for Protamine 2 Proteins (PRM2)

protamine-2 , sperm histone P2 , sperm protamine P2 , sperm protamine-P2 , cancer/testis antigen family 94, member 2 , Pro-protamine P2 , sperm basic nulcear protein , Protamine P2 , Protamine-2 , Sperm histone P2 , Sperm protamine P2 , protamine 2 , protamine p2

GENE ID SPECIES
19119 Mus musculus
25345 Rattus norvegicus
281424 Bos taurus
397486 Sus scrofa
5620 Homo sapiens
783623 Bos taurus
453921 Pan troglodytes
100970844 Pan paniscus
100401666 Callithrix jacchus
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