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anti-Protease, serine, 3 (PRSS3) Antibodies

PRSS3 encodes a trypsinogen, which is a member of the trypsin family of serine proteases. Additionally we are shipping PRSS3 Proteins (8) and PRSS3 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PRSS3 5646 P35030
PRSS3 22073  
PRSS3 286911 P08426
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Top anti-PRSS3 Antibodies at antibodies-online.com

Showing 10 out of 87 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram) using Trypsin-3 / PRSS3  Antibody (N-term), followed by FITC-conjugated goat-anti-rabbit secondary antibodies. Immunohistochemistry analysis in human pancreas tissue (Formalin-fixed, Paraffin-embedded) using Trypsin-3 / PRSS3  Antibody  (N-term), followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PRSS3 antibody for IHC; Clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Flow cytometric analysis of HL-60 cells using RSS3 Antibody (Center) Cat.-No AP53469PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Formalin fixed and paraffin embedded human pancreas tissue reacted with RSS3 Antibody (Center) followed by peroxidase conjugation of the secondary antibody and DAB staining. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-PRSS3 Antibody Titration: 0.2-1 ug/mlPositive Control: Human Muscle WB Suggested Anti-PRSS3  Antibody Titration: 0.2-1 µg/mL  Positive Control: Human Muscle 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB PRSS3 Antibody (Center) (ABIN655869) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB PRSS3 Antibody (N-term) (ABIN654446) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB Western blot (WB) analysis of Trypsin-3 antibody in extracts from A549 cells 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of Trypsin 3 expression in MDAMB231 (A), HL60 (B) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA   100 μg Log in to see 16 Days
$163.90
Details
Human Rabbit Un-conjugated WB PRSS3 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Alkaline Phosphatase (AP) FACS, IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

PRSS3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-PRSS3 Antibodies

  1. Human Polyclonal PRSS3 Primary Antibody for EIA, FACS - ABIN955348 : Salameh, Robinson, Navaneetham, Sinha, Madden, Walsh, Radisky: The amyloid precursor protein/protease nexin 2 Kunitz inhibitor domain is a highly specific substrate of mesotrypsin. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for ABIN955348

  2. Human Polyclonal PRSS3 Primary Antibody for EIA, FACS - ABIN955347 : Jiang, Cao, Ren, Gao, Bhakta, Zhang, Cao, Dong, Zang, Zhang, Wong, Hiley, Crnogorac-Jurcevic, Lemoine, Wang: PRSS3 promotes tumour growth and metastasis of human pancreatic cancer. in Gut 2010 (PubMed)
    Show all 2 references for ABIN955347

  3. Human Polyclonal PRSS3 Primary Antibody for ELISA - ABIN1999367 : Venter, Adams, Myers, Li, Mural, Sutton, Smith, Yandell, Evans, Holt, Gocayne, Amanatides, Ballew, Huson, Wortman, Zhang, Kodira, Zheng, Chen, Skupski, Subramanian, Thomas, Zhang, Gabor Miklos et al.: The sequence of the human genome. ... in Science (New York, N.Y.) 2001 (PubMed)

More Antibodies against PRSS3 Interaction Partners

Human Protease, serine, 3 (PRSS3) interaction partners

  1. Data show that silencing tumor-endothelial cells (EC) for trypsinogen 4 accumulated tissue factor pathway inhibitor-2 (TFPI-2 (show TFPI2 Antibodies)) in the matrix.

  2. These findings suggest that inhibitor cleavage represents a functional adaptation of mesotrypsin that may have evolved in response to positive selection pressure.

  3. High PRSS3 expression in EOC tissues was significantly associated with advanced FIGO stage and lymph node metastasis.

  4. Data suggest that mesotrypsin cleavage of Kunitz domains may contribute to cancer progression.

  5. Mesotrypsin generated saposins A-D from prosaposin (show PSAP Antibodies), and mature caspase-14 (show CASP14 Antibodies) contributed to this process by activating mesotrypsinogen to mesotrypsin. Knockdown of these proteases markedly down-regulated saposin A synthesis in skin equivalent models.

  6. extra-pancreatic trypsinogen 3 is produced by esophageal adenocarcinoma cells and activates PAR-2 (show F2RL1 Antibodies) in an autocrine manner.

  7. IFN regulatory factor 2 (Irf2 (show IRF2 Antibodies)) has a regulatory role in trypsinogen5 gene transcription, which is resistant to a major endogenous trypsin inhibitor, Spink3 (show SPINK1 Antibodies)

  8. Report PRSS3/mesotrypsin upregulation in breast cancer cells and identify CD109 (show CD109 Antibodies) as the functional proteolytic target of mesotrypsin.

  9. PRSS3 plays an important role in the progression, metastasis and prognosis of human pancreatic cancer.

  10. Investigation did not reveal an association between PRSS3 variants and chronic pancreatitis.

Mouse (Murine) Protease, serine, 3 (PRSS3) interaction partners

  1. Mesotrypsin generated saposins A-D from prosaposin (show PSAP Antibodies), and mature caspase-14 (show CASP14 Antibodies) contributed to this process by activating mesotrypsinogen to mesotrypsin. Knockdown of these proteases markedly down-regulated saposin A synthesis in skin equivalent models.

  2. Intra-acinar activation of trypsinogen is sufficient to initiate acute pancreatitis.

  3. the initiation of acute pancreatitis depends on endocytic vacuole formation and trypsinogen activation in pancreatic acinar cells

PRSS3 Antigen Profile

Protein Summary

This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is expressed in the brain and pancreas and is resistant to common trypsin inhibitors. It is active on peptide linkages involving the carboxyl group of lysine or arginine. This gene is localized to the locus of T cell receptor beta variable orphans on chromosome 9. Four transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with PRSS3

  • trypsin-3 (CpipJ_CPIJ016105) antibody
  • protease, serine, 3 (PRSS3) antibody
  • protease, serine, 3 (Prss3) antibody
  • trypsin III (trp-iii) antibody
  • MTG antibody
  • PRSS4 antibody
  • T9 antibody
  • Tb antibody
  • Try3 antibody
  • TRY4 antibody

Protein level used designations for PRSS3

trypsin-3 , brain trypsinogen , mesotrypsin , mesotrypsinogen , pancreatic trypsinogen III , protease, serine, 4 (trypsin 4, brain) , trypsin III , trypsin IV , trypsinogen 4 , trypsinogen 5 , trypsinogen IV , trypsin 3 , trypsinogen 15 , cationic trypsin III , cationic trypsin-3 , cationic trypsinogen , pretrypsinogen III

GENE ID SPECIES
6049341 Culex quinquefasciatus
5646 Homo sapiens
22073 Mus musculus
286911 Rattus norvegicus
100137024 Salmo salar
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