You are viewing an incomplete version of our website. Please click to reload the website as full version.

Protease, serine, 3 Proteins (PRSS3)

PRSS3 encodes a trypsinogen, which is a member of the trypsin family of serine proteases. Additionally we are shipping PRSS3 Antibodies (85) and PRSS3 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PRSS3 5646 P35030
Mouse PRSS3 PRSS3 22073  
Rat PRSS3 PRSS3 286911 P08426
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top PRSS3 Proteins at antibodies-online.com

Showing 8 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 10 μg Log in to see 16 Days
$206.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast REACT_Atlantic Salmon His tag   1 mg Log in to see 56 to 66 Days
$2,557.50
Details
Yeast Mosquito His tag   1 mg Log in to see 56 to 66 Days
$2,570.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$388.93
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 16 to 21 Days
$314.29
Details

PRSS3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

Top referenced PRSS3 Proteins

  1. Human PRSS3 Protein expressed in Human Cells - ABIN2004863 : Venter, Adams, Myers, Li, Mural, Sutton, Smith, Yandell, Evans, Holt, Gocayne, Amanatides, Ballew, Huson, Wortman, Zhang, Kodira, Zheng, Chen, Skupski, Subramanian, Thomas, Zhang, Gabor Miklos et al.: The sequence of the human genome. ... in Science (New York, N.Y.) 2001 (PubMed)

More Proteins for Protease, serine, 3 (PRSS3) Interaction Partners

Human Protease, serine, 3 (PRSS3) interaction partners

  1. Data show that silencing tumor-endothelial cells (EC) for trypsinogen 4 accumulated tissue factor pathway inhibitor-2 (TFPI-2 (show TFPI2 Proteins)) in the matrix.

  2. These findings suggest that inhibitor cleavage represents a functional adaptation of mesotrypsin that may have evolved in response to positive selection pressure.

  3. High PRSS3 expression in EOC tissues was significantly associated with advanced FIGO stage and lymph node metastasis.

  4. Data suggest that mesotrypsin cleavage of Kunitz domains may contribute to cancer progression.

  5. Mesotrypsin generated saposins A-D from prosaposin (show PSAP Proteins), and mature caspase-14 (show CASP14 Proteins) contributed to this process by activating mesotrypsinogen to mesotrypsin. Knockdown of these proteases markedly down-regulated saposin A synthesis in skin equivalent models.

  6. extra-pancreatic trypsinogen 3 is produced by esophageal adenocarcinoma cells and activates PAR-2 (show F2RL1 Proteins) in an autocrine manner.

  7. IFN regulatory factor 2 (Irf2 (show IRF2 Proteins)) has a regulatory role in trypsinogen5 gene transcription, which is resistant to a major endogenous trypsin inhibitor, Spink3 (show SPINK1 Proteins)

  8. Report PRSS3/mesotrypsin upregulation in breast cancer cells and identify CD109 (show CD109 Proteins) as the functional proteolytic target of mesotrypsin.

  9. PRSS3 plays an important role in the progression, metastasis and prognosis of human pancreatic cancer.

  10. Investigation did not reveal an association between PRSS3 variants and chronic pancreatitis.

Mouse (Murine) Protease, serine, 3 (PRSS3) interaction partners

  1. Mesotrypsin generated saposins A-D from prosaposin (show PSAP Proteins), and mature caspase-14 (show CASP14 Proteins) contributed to this process by activating mesotrypsinogen to mesotrypsin. Knockdown of these proteases markedly down-regulated saposin A synthesis in skin equivalent models.

  2. Intra-acinar activation of trypsinogen is sufficient to initiate acute pancreatitis.

  3. the initiation of acute pancreatitis depends on endocytic vacuole formation and trypsinogen activation in pancreatic acinar cells

PRSS3 Protein Profile

Protein Summary

This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is expressed in the brain and pancreas and is resistant to common trypsin inhibitors. It is active on peptide linkages involving the carboxyl group of lysine or arginine. This gene is localized to the locus of T cell receptor beta variable orphans on chromosome 9. Four transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with Protease, serine, 3 Proteins (PRSS3)

  • trypsin-3 (CpipJ_CPIJ016105)
  • protease, serine, 3 (PRSS3)
  • protease, serine, 3 (Prss3)
  • trypsin III (trp-iii)
  • MTG protein
  • PRSS4 protein
  • T9 protein
  • Tb protein
  • Try3 protein
  • TRY4 protein

Protein level used designations for Protease, serine, 3 Proteins (PRSS3)

trypsin-3 , brain trypsinogen , mesotrypsin , mesotrypsinogen , pancreatic trypsinogen III , protease, serine, 4 (trypsin 4, brain) , trypsin III , trypsin IV , trypsinogen 4 , trypsinogen 5 , trypsinogen IV , trypsin 3 , trypsinogen 15 , cationic trypsin III , cationic trypsin-3 , cationic trypsinogen , pretrypsinogen III

GENE ID SPECIES
6049341 Culex quinquefasciatus
5646 Homo sapiens
22073 Mus musculus
286911 Rattus norvegicus
100137024 Salmo salar
Selected quality suppliers for PRSS3 Proteins (PRSS3)
Did you look for something else?