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Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1 (PSMC1) ELISA Kits

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. Additionally we are shipping PSMC1 Antibodies (26) and PSMC1 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse PSMC1 PSMC1 19179 P62192
Anti-Human PSMC1 PSMC1 5700 P62191
Anti-Rat PSMC1 PSMC1 117263 P62193
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More ELISA Kits for PSMC1 Interaction Partners

Mouse (Murine) Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1 (PSMC1) interaction partners

  1. In Psmc1(+/-)primary mouse embryonic fibroblasts we found decreased PSMC1 protein expression, altered assembly of the 26S proteasome (show Psmd4 ELISA Kits) and G2/M cell cycle arrest.

  2. Caspase-3 (show CASP3 ELISA Kits) cleaves specific 19 S proteasome subunits in skeletal muscle stimulating proteasome activity

Human Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1 (PSMC1) interaction partners

  1. P26s4 Associates with the C-Terminal Region of TOPORS.

  2. Our results suggest that there is no association between variations or haplotypes in the PSMC1 gene and Parkinson's disease

  3. Caspase-3 (show CASP3 ELISA Kits) cleaves specific 19 S proteasome subunits in skeletal muscle stimulating proteasome activity

  4. Hepatocytes dying because of inhibition of proteasome function produce massive quantities of the proinflammatory chemokine (show CCL1 ELISA Kits) IL-8 (show IL8 ELISA Kits), possibly resulting in neutrophil infiltration, increased inflammation, and liver injury.

  5. Psmc1 conditional knock-out mice demonstrate that 26S proteasomal dysfunction is sufficient to trigger neurodegenerative disease.

Cow (Bovine) Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1 (PSMC1) interaction partners

  1. Thus, the results of our study suggest that the H-FABP (show FABP3 ELISA Kits) and PSMC1 gene polymorphisms could be used as genetic markers in marker-assisted selection for improving Qinchuan beef cattle

  2. reveal critical roles of COOH termini of Rpt subunits of PA700 in the assembly and activation of eukaryotic 26 S proteasome[PA700 proteasome activator ]

  3. data show that animals with AA genotype have a lower food intake, grow faster, are longer in the body & have less backfat & bigger loin muscle; PSMC1 gene was expressed mainly in lung, testis, and spleen; mapped PSMC1 gene on BTA10

PSMC1 Antigen Profile

Antigen Summary

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit and a 20S core alpha subunit interact specifically with the hepatitis B virus X protein, a protein critical to viral replication. This subunit also interacts with the adenovirus E1A protein and this interaction alters the activity of the proteasome. Finally, this subunit interacts with ataxin-7, suggesting a role for the proteasome in the development of spinocerebellar ataxia type 7, a progressive neurodegenerative disorder.

Gene names and symbols associated with PSMC1

  • protease (prosome, macropain) 26S subunit, ATPase 1 (Psmc1) antibody
  • proteasome (prosome, macropain) 26S subunit, ATPase, 1 (PSMC1) antibody
  • proteasome (prosome, macropain) 26S subunit, ATPase, 1 (Psmc1) antibody
  • AI325227 antibody
  • P26S4 antibody
  • p56 antibody
  • s4 antibody

Protein level used designations for PSMC1

26S protease regulatory subunit 4 , 26S proteasome AAA-ATPase subunit RPT2 , proteasome 26S subunit ATPase 1 , proteasome 26S ATPase subunit 1 , proteasome 26S subunit, ATPase, 1 , P26s4 , peptidase (prosome, macropain) 26S subunit, ATPase 1 , protease (prosome, macropain) 26S subunit, ATPase 1 , 26S ATPase complex subunit 4

GENE ID SPECIES
19179 Mus musculus
5700 Homo sapiens
117263 Rattus norvegicus
506238 Bos taurus
395804 Gallus gallus
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