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Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1 Proteins (PSMC1)

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. Additionally we are shipping PSMC1 Antibodies (26) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PSMC1 19179 P62192
PSMC1 5700 P62191
PSMC1 117263 P62193
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Top PSMC1 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$823.90
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,228.50
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$3,232.17
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PSMC1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,
Rat (Rattus)

More Proteins for Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1 (PSMC1) Interaction Partners

Mouse (Murine) Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1 (PSMC1) interaction partners

  1. In Psmc1(+/-)primary mouse embryonic fibroblasts we found decreased PSMC1 protein expression, altered assembly of the 26S proteasome (show Psmd4 Proteins) and G2/M cell cycle arrest.

  2. Caspase-3 (show CASP3 Proteins) cleaves specific 19 S proteasome subunits in skeletal muscle stimulating proteasome activity

Human Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1 (PSMC1) interaction partners

  1. P26s4 Associates with the C-Terminal Region of TOPORS (show TOPORS Proteins).

  2. Our results suggest that there is no association between variations or haplotypes in the PSMC1 gene and Parkinson's disease

  3. Caspase-3 (show CASP3 Proteins) cleaves specific 19 S proteasome subunits in skeletal muscle stimulating proteasome activity

  4. Hepatocytes dying because of inhibition of proteasome function produce massive quantities of the proinflammatory chemokine (show CCL1 Proteins) IL-8 (show IL8 Proteins), possibly resulting in neutrophil infiltration, increased inflammation, and liver injury.

  5. Psmc1 conditional knock-out mice demonstrate that 26S proteasomal dysfunction is sufficient to trigger neurodegenerative disease.

Cow (Bovine) Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1 (PSMC1) interaction partners

  1. Thus, the results of our study suggest that the H-FABP (show FABP3 Proteins) and PSMC1 gene polymorphisms could be used as genetic markers in marker-assisted selection for improving Qinchuan beef cattle

  2. reveal critical roles of COOH termini of Rpt subunits of PA700 in the assembly and activation of eukaryotic 26 S proteasome[PA700 proteasome activator ]

  3. data show that animals with AA genotype have a lower food intake, grow faster, are longer in the body & have less backfat & bigger loin muscle; PSMC1 gene was expressed mainly in lung, testis, and spleen; mapped PSMC1 gene on BTA10

PSMC1 Protein Profile

Protein Summary

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit and a 20S core alpha subunit interact specifically with the hepatitis B virus X protein, a protein critical to viral replication. This subunit also interacts with the adenovirus E1A protein and this interaction alters the activity of the proteasome. Finally, this subunit interacts with ataxin-7, suggesting a role for the proteasome in the development of spinocerebellar ataxia type 7, a progressive neurodegenerative disorder.

Gene names and symbols associated with PSMC1

  • protease (prosome, macropain) 26S subunit, ATPase 1 (Psmc1)
  • proteasome (prosome, macropain) 26S subunit, ATPase, 1 (PSMC1)
  • proteasome (prosome, macropain) 26S subunit, ATPase, 1 (Psmc1)
  • AI325227 protein
  • P26S4 protein
  • p56 protein
  • s4 protein

Protein level used designations for PSMC1

26S protease regulatory subunit 4 , 26S proteasome AAA-ATPase subunit RPT2 , proteasome 26S subunit ATPase 1 , proteasome 26S ATPase subunit 1 , proteasome 26S subunit, ATPase, 1 , P26s4 , peptidase (prosome, macropain) 26S subunit, ATPase 1 , protease (prosome, macropain) 26S subunit, ATPase 1 , 26S ATPase complex subunit 4

GENE ID SPECIES
19179 Mus musculus
5700 Homo sapiens
117263 Rattus norvegicus
506238 Bos taurus
395804 Gallus gallus
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